Sentences with phrase «finding orthologs»
Ward N, Moreno - Hagelsieb G. Quickly finding orthologs as reciprocal best hits with BLAT, LAST, and UBLAST: How much do we miss?.
http://www.jgenomics.com/ Not exact matches
Humans have an ortholog of the murine Nrk gene, and considering that the gene expression pattern in breast tumor in Nrk mutant mice was similar to that in human luminal B breast cancer, the findings of this study may lead to further understanding of the mechanisms of human breast cancer suppression and to advances in its diagnosis and therapy.
The ortholog genes that were found to be associated with cartilage development, along with bmp which acts as a key member gene, are known to be involved in the Wnt signaling pathway (Kim et al., 2013; Lin & Hankenson, 2011).
Whereas 12 of 16 annotations were confirmed by RT - PCR in human tissues, for only seven genes mouse orthologs could be identified and found to be expressed.
Second, we find that DAF - 16, the FOXO ortholog, is important for maintaining multipotency during dauer.