Sentences with phrase «findings in a larger cohort»

Replication of these findings in a larger cohort is necessary, although it lies beyond the scope of this thesis.

Not exact matches

Challenge number one was how hard it was to find a large number of research subjects working in similar jobs, who could divide into work - at - home and work - at - the - office cohorts, and who were willing to cooperate with the researchers over a long enough period of time.

The process whereby the liberal Protestant colleges and universities were separated from their sponsoring churches in the period 1870 - 1910 may have been repeating itself during a comparable period, 1950 - 1990, among the very large cohort of universities and colleges that were founded as Catholic.

In conclusion, in a large American cohort, we found that vegetarian dietary patterns were associated with lower mortalitIn conclusion, in a large American cohort, we found that vegetarian dietary patterns were associated with lower mortalitin a large American cohort, we found that vegetarian dietary patterns were associated with lower mortality.

Most studies of homebirth in other countries have found no statistically significant differences in perinatal outcomes between home and hospital births for women at low risk of complications.36, 37,39 However, a recent study in the United States showed poorer neonatal outcomes for births occurring at home or in birth centres.40 A meta - analysis in the same year demonstrated higher perinatal mortality associated with homebirth41 but has been strongly criticised on methodological grounds.5, 42 The Birthplace in England study, 43 the largest prospective cohort study on place of birth for women at low risk of complications, analysed a composite outcome, which included stillbirth and early neonatal death among other serious morbidity.

This also was found in a large, retrospective cohort study of 15,759 nulliparous women even in a group of women whose second stage progressed beyond 4 hours (29).

We found a direct association between never or curtailed lactation and incident hypertension in a large, prospective cohort of parous women.

Khachaturian says a proper test of Roses» findings — using Roses» methods in a larger cohort of patients — has not yet been done.

Additional studies in larger cohorts will be needed to validate these findings, and more biomarkers will be needed to get the completely accurate set needed to screen the general population with the long term goal of identifying precursor lesions before they become malignant.

Findings from this UK cohort are confirmed by evidence for adult - onset ADHD world - wide: a study from Brazil will be published by JAMA Psychiatry alongside this research, which also identified a large proportion of adults with ADHD as not having the disorder in childhood.

«We hope to design a program that draws from these findings and more research on mindfulness meditation is needed in a larger cohort of mothers,» added Golfenshtein.

Conducting a cross-sectional study of a large cohort of patients with different levels of cognitive impairment and different disease stages, the researchers found that the amounts of a TREM2 fragment in the cerebrospinal fluid were highest during early stages characterized by mild cognitive impairment symptoms.

They analyzed a large cohort of human patient samples from the human kidney biobank managed by Susztak and found that the interconversion might also occur in patients with kidney disease and likely contributes to a condition when the kidneys can not remove enough acid from the body.

Surprisingly, we found the same signature in large cohorts of women without the BRCA1 mutation and it was able to predict breast cancer risk several years before diagnosis.»

«We found a significant relation between brown fat activity and miR - 92a that needs to be proven in larger cohorts,» said co-first author Joschka Johannes Buyel, a PhD student in Prof. Pfeifer's lab.

The NYGC and its founding member institutions are conducting additional studies involving Watson to help accelerate the discovery of potentially actionable sequence variants in various types of cancer, including an ongoing study that involves DNA and RNA from a larger cohort of glioblastoma patients, and a study of 200 patients with different types of cancer.

Notably, the West African cohort has been useful for refining the association signals found in European and Asian ancestry populations; it has provided some of the earliest evidence for how relatively diverse populations might facilitate fine - mapping of loci originally identified in more homogeneous populations characterized by larger regions of strong linkage disequilibrium.

Data shared through RD ‐ Connect is accessible beyond the usual institutional and national boundaries and researchers across the world can benefit from the opportunity to work with others with an interest in the same field, pool data to create larger cohorts, find confirmatory cases, and access samples for further study.

Our findings are potentially applicable to early disease detection, and future test development should focus on longitudinal sampling of the microbiota to monitor for changes in microbial diversity in a larger cohort of patients.

Conversely, within non-diabetic populations, periods of IER (75 - 85 % ER on restricted days) do not typically affect fasting glucose levels 37, 41, 45, 48 or HbA1c 41, 48; results of which can often be replicated by short term CER studies.62 - 65These findings are unsurprising given that frank hyperglycaemia within the T2DM diagnostic range is effectively a late - stage manifestation of IR, which along with compensatory increases insulin secretion, can precede the onset of T2DM by many years.66, 67 Findings from one large scale prospective cohort study, Whitehall II, reveal a sharp increase in the trajectory towards fasting hyperglycaemia which is only detectable three years prior to diagnosis with T2DM.67 Consequently, it can be argued that changes in circulating insulin concentrations, fasting (hepatic) insulin sensitivity and glucose uptake / clearance are more sensitive markers of deteriorating glucose control than fasting glycaemia in non - diabeticsfindings are unsurprising given that frank hyperglycaemia within the T2DM diagnostic range is effectively a late - stage manifestation of IR, which along with compensatory increases insulin secretion, can precede the onset of T2DM by many years.66, 67 Findings from one large scale prospective cohort study, Whitehall II, reveal a sharp increase in the trajectory towards fasting hyperglycaemia which is only detectable three years prior to diagnosis with T2DM.67 Consequently, it can be argued that changes in circulating insulin concentrations, fasting (hepatic) insulin sensitivity and glucose uptake / clearance are more sensitive markers of deteriorating glucose control than fasting glycaemia in non - diabeticsFindings from one large scale prospective cohort study, Whitehall II, reveal a sharp increase in the trajectory towards fasting hyperglycaemia which is only detectable three years prior to diagnosis with T2DM.67 Consequently, it can be argued that changes in circulating insulin concentrations, fasting (hepatic) insulin sensitivity and glucose uptake / clearance are more sensitive markers of deteriorating glucose control than fasting glycaemia in non - diabetics.68 - 70

Yet the reduction in LDL cholesterol from reducing saturated fat intake seems to be specific to large, buoyant (type A) LDL particles, when in factit is the small, dense (type B) particles (responsive to carbohydrate intake) that are implicated in cardiovascular disease.Indeed, recent prospective cohort studies have not supported any significant association between saturated fat intake and cardiovascular risk Instead, saturated fat has been found to be protective.»

And claiming that, because they are not considered paleo foods by your favourite gurus, it must mean grains and legumes are bad for us simply flies in the face of the evidence: «In summary, these data from 2 large prospective cohort studies consistently found significant inverse associations of whole grain intake and mortality, especially CVD mortalitin the face of the evidence: «In summary, these data from 2 large prospective cohort studies consistently found significant inverse associations of whole grain intake and mortality, especially CVD mortalitIn summary, these data from 2 large prospective cohort studies consistently found significant inverse associations of whole grain intake and mortality, especially CVD mortality.

A 2016 study published in The BMJ looked at a large cohort of women and found that those who ate four or more servings of potatoes a week had a higher risk of blood pressure compared to women who ate potatoes less than once a month.

43 % of New Teachers in New Jersey Plan to Leave Classroom Teaching; Nearly Half are Mid-Career Entrants At a time when U.S. schools will need to hire over two million new teachers to serve a growing number of students and replace a large cohort of retiring teachers, new research findings from the Harvard Graduate School of Education suggest that 43 % of new teachers do not anticipate staying in the classroom as full - time teachers for their entire careers.

At a time when U.S. schools will need to hire over two million new teachers to serve a growing number of students and replace a large cohort of retiring teachers, new research findings from the Harvard Graduate School of Education suggest that 43 % of new teachers do not anticipate staying in the classroom as full - time teachers for their entire careers.

We're going to recruit 20 schools over the next few years and we're going to do that in two cohorts — we're going to do that in 10 schools next year and then another 10 schools the following year (we're actually doing recruitment at the moment for that), and we're going to test it with a larger sample to see whether our initial positive findings hold and whether they have the same benefits that we've seen so far.

Tracking four cohorts of students throughout Florida, I find that large differences in math achievement across racial lines exist as early as elementary school and persist through high school.

A team of scientists has investigated a large cohort of British children to see to what extent symmetrical faces in human beings implies better health; they have published their findings at the Royal Society.

First, associations between depression and cortisol in pregnancy were not found in one large population based cohort study20 and may only be significant in the presence of antidepressant medication21 or co-morbid anxiety.22 Second, studies that tested either direct associations between antenatal maternal cortisol levels on infant or child outcomes or the mediational role of antenatal cortisol in associations between antenatal depression and outcomes yield mixed findings and typically have relied on small samples.23 Postpartum depression has been associated with a range of problems in infants» and young children's development.

Our GUS finding for family socio - economic disadvantage (as indicated here by lower parental education) ties in with the negative effect of low family socio - economic status on the quality of both mothers» and fathers» relations with three year - old children in another large birth cohort, the UK Millennium Cohort Study (Malmberg & Flouri, cohort, the UK Millennium Cohort Study (Malmberg & Flouri, Cohort Study (Malmberg & Flouri, 2011).

With the use of a large prospective cohort, we found evidence of differences in fish and processed food consumption among mothers of EOP vs. Low CP children in pregnancy, and in children's processed food consumption at 3 years.