Sentences with phrase «finds microcephaly»

Not exact matches

After taking samples and conducting brain scans, the researchers found that 41 percent of mothers of babies with microcephaly tested positive for Zika infection in blood or cerebrospinal fluid samples, compared with none of those whose babies did not have microcephaly.

As most studies have only carefully examined infants with presumed or confirmed congenital ZIKV infection who have microcephaly, more studies are needed to understand ocular findings in those infants with congenital ZIKV infection without microcephaly.

The finding strengthens the evidence that a mother's Zika infection during pregnancy raises her baby's risk of microcephaly and other brain malformations.

This finding paves the way to study whether p53 inhibitors could provide the basis of a future treatment to prevent microcephaly.

The team who found a range of fetal conditions beyond microcephaly, all linked to the virus, suggest calling it Zika virus congenital syndrome

The finding of virus in the brain could also be important, since the most devastating impact of the current outbreak in Brazil appears to be children of infected mothers born with microcephaly — abnormally small heads and, in some cases, incomplete brain development.

The virus has been found in the amniotic fluid of two fetuses diagnosed with microcephaly via ultrasound.

It has also been found in tissues of a baby with microcephaly that died shortly after birth.

These findings may correlate with disrupted brain development, but direct evidence for a link between Zika virus and microcephaly is more likely to come from clinical studies, the researchers say.

The findings — so far observed only in cells and minibrains grown in the lab — offer a possible explanation for the misshapen heads that are the hallmark of microcephaly, a condition that afflicts some babies infected with Zika.

Though much of the concern in the media regarding the toxic effects of Zika virus has focused on brain findings of microcephaly, the researchers noted that there are a variety of brain abnormalities that can be found in fetuses exposed to the virus, including gray and white matter volume loss, brainstem abnormalities, calcifications, and a condition called ventriculomegaly, where the ventricles, or fluid filled spaces in the brain, are enlarged.

«Likely biological link found between Zika virus, microcephaly: Discovery with lab - grown stem cells could be used to identify potential therapies.»

«Studies of fetuses and babies with the telltale small brains and heads of microcephaly in Zika - affected areas have found abnormalities in the cortex, and Zika virus has been found in the fetal tissue,» says Guo - li Ming, M.D., Ph.D., a professor of neurology, neuroscience, and psychiatry and behavioral science at Johns Hopkins» Institute for Cell Engineering.

Such techniques have the potential to enhance research into the origins of neurodevelopmental and neuropsychiatric disorders such as microcephaly, lissencephaly, autism and schizophrenia, which are thought to affect cell types not found in the mouse models that are often used to study such diseases.

They found an increase in microcephaly cases and of Guillain - Barré syndrome.

Researchers have already documented an increase of microcephaly cases coinciding with the outbreak and have found evidence of the virus in brains of newborns who died, as well as in fluid from the placenta of infected pregnant women.

But Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine, said its findings offer «potentially important» new information about the link between Zika and microcephaly.

What seems to be universal is that microcephaly is not the sole finding but is a consequence of several brain injuries.

The birth prevalence of neonatal microcephaly and other central nervous system malformations greatly increased between 2015 and mid-2016 in Brazil.1 - 3 Several reports1,2,4 - 6 suggested an association between these findings and Zika virus (ZIKV) infection during outbreaks in Brazil and French Polynesia.

The 3 largest case series of infants with microcephaly also reporting congenital contractures found that, among 35, 48, and 52 infants with microcephaly and presumed congenital ZIKV infection, isolated clubfoot occurred in 14 %, 10.4 %, and 3.8 % and arthrogryposis in 11 %, 10.4 %, and 5.7 %, respectively.36 - 38 Among a series of 104 infants under clinical investigation, 7 (6.7 %) with presumed (5 infants) and laboratory - confirmed (2 infants) congenital ZIKV infection had arthrogryposis; 6 of these infants had a head circumference of at least 2 SD below the mean.41 All had bilateral congenital hip dislocation, which previously has been reported to occur in 30 % to 40 % of children with arthrogryposis of various etiologies and 3 of 7 had dislocation or partial dislocation of 1 or both knees.41, 57

Structural eye anomalies (in particular, microphthalmia and coloboma), cataracts, intraocular calcifications, and posterior ocular findings have been reported in infants with presumed and laboratory - confirmed prenatal ZIKV infection; however, posterior findings have been the most prevalent.21,25,28,33,35,36,41 - 43 Case series report chorioretinal atrophy, focal pigmentary mottling of the retina, and optic nerve atrophy / anomalies.28, 34,37,41 - 43,55 Series of 20 or more infants with presumed ZIKV - associated microcephaly report ocular findings in 24 % to 55 %.28, 33,42 In one study, testing for ZIKV IgM was performed in 24 of 40 infants (60 %) with microcephaly and the results were positive in the cerebrospinal fluid in 100 % of those tested.42 The proportion of infants with ocular lesions did not differ in those with and without testing.42 In that series, first trimester maternal infection and smaller head circumference significantly correlated with the presence of abnormal ocular findings.42

Objective To evaluate the ocular findings in infants with microcephaly associated with presumed intrauterine ZIKV infection in Salvador, Bahia, Brazil.

To evaluate the ocular findings in infants with microcephaly associated with presumed intrauterine ZIKV infection in Salvador, Bahia, Brazil.

Addressing the Zika outbreaks has been a challenge for health officials, and since the first microcephaly cases were reported in Brazil last year, there has been a nationwide effort to find practical solutions to the growing threat of the virus.

The authors note their findings could downplay the frequency in which hearing loss occurs in children infected with Zika in the womb because they only tested children with microcephaly, which is characterized by an abnormally small head and in some cases brain damage.

A recent increase in the prevalence of microcephaly in newborn infants and vision - threatening findings in these infants is likely associated with the rapid spread of ZIKV.

More than half the infants had microcephaly, brain calcifications, loss of brain tissue volume, and other brain structural abnormalities, the researchers found.

Lyle R. Petersen, MD, director of vector - borne diseases at the CDC, told the New York Times earlier this week that the agency had found the Zika virus in four Brazilian babies; two died in the womb, and two had microcephaly and died shortly after birth.

To see the alternative story about Zika infections, Mike Adams, the Health Ranger, did some studies on Brazilian populations with a high incidence of microcephaly and did find that the incidences of microcephaly corresponded more with environmental toxins.