Sentences with phrase «first chimeric»

Using the subgerminal cavity injection method with a Cas9 - strain of Rock Pigeons would allow the observation of phenotypes in the first chimeric generation; saving time on selecting individuals for breeding pure, fully - edited strains of genotypes that successfully capitulate the desired phenotype.

The world's first chimeric monkeys were created in a laboratory last year, and they offer surprising new insights into embryonic stem cell therapy: One reason for often - poor treatment outcomes may be that we're using embryos that are, strangely, just too old.

Not exact matches

The race to become the first company with a chimeric antigen receptor T - cell (CAR - T) cancer therapy on the market has entered its final leg, and Kite Pharma now appears to have a big advantage.

Although it wasn't the first time chimeric pigs were created, it was the first time they came about using cloned pluripotent cells.

«NYGC is thrilled to have this work be our first published example of the explosive power of collaborations between deeply invested biologists like those in the Simon lab including Elana Simon, and thoughtful bioinformatics scientists like Nicolas Robine and NYGC team, who worked together so effectively with the tools of genomic sequencing and analysis to discover this new chimeric protein and cancer target,» says Robert Darnell, head of Rockefeller's Laboratory of Molecular Neuro - Oncology, HHMI investigator, and president and scientific director of NYGC.

In their latest study, Potash and colleagues describe the efficient and reproducible transmission of chimeric HIV from infected male mice to uninfected females via mating, providing the first report of HIV transmission by coitus in an animal model.

Zelig Eshhar and colleagues first use the T - body approach, employing chimeric receptors composed of an antibody recognition unit linked to T cell activation domains, to redirect T cells to recognize and attack tumor cells.

The new results — from trials for patients with advanced lymphoma, multiple myeloma, and pancreatic cancer — expand on Penn's work with chimeric antigen receptor (CAR) therapies, building on findings in patients with chronic lymphocytic leukemia and acute lymphoblastic leukemia dating back to the start of the first clinical trial in 2010.

First, they remain in the offspring after birth and are related to the HLA genes, and second, chimeric cells are not merely present in the children — but they are active, as shown by the attacks they mount against the child's body.

The first and only chimeric recombinant canine Lyme disease vaccine.