Sentences with phrase «first clinical trial for»

«The long awaited first clinical trial for a drug to treat MHE is now a reality.

The hospital opened in 1913 to treat tuberculosis patients and was the site of the first clinical trials for the hydrazides treatment that eventually led to the cure of the disease, according to the EDC.

In addition, ViaCyte launched the first clinical trials for stem cell - derived islet replacement therapies for type 1 diabetes.

Not exact matches

In those areas that we have mapped, it typically takes us a few hours to go from a mechanism - inspired idea for treating a disease to knowing the companies that might have relevant clinical and preclinical assets to license, the companies from whom a candidate could be commissioned, trial designs and endpoints, competing and complementary agents, current and future standard of care, market size, comparable pricing, financing strategy, and potential acquirers, all meant to enable a thoughtful first - pass assessment of whether an idea could be worth a much deeper assessment.

Cambridge, MA — March 30, 2017 — Aura Biosciences, a biotechnology company developing a new class of therapies to target and selectively destroy cancer cells using viral nanoparticle conjugates, announced today that it has enrolled and dosed the first patient in its Phase 1b clinical trial of light - activated AU - 011, an investigational, first - in - class targeted therapy in development for the treatment of ocular melanoma, a rare and life - threatening disease.

As a board - certified internist at Cedars - Sinai Medical Center in Beverly Hills, Dr. Udani was among the first physicians in America to become a certified physician investigator for clinical trials.

«We chose to use Axiom Foods» Oryzatein ® ingredient,» said CEO of Growing Naturals, David Janow, «because it is the only 90 % brown rice protein isolate that is made with a proprietary enzyme fractioning method and was shown in a clinical trial for the first time to equal animal - based whey protein in building and maintaining muscle.»

(Culver City, CA August 27, 2013)-- After Oryzatein ® was recognized as the first plant - based rice protein to equal animal - based whey protein for muscle building and repair in a clinical trial published last month, an «Oryzatein ® Inside» endicia is being provided to manufacturers who use the ingredient in their food products.

Setting the global pace and standards for not only the industry but national certifying bodies and agencies, Axiom's ingredients have been featured in ground - breaking double blind clinical trials at a major American university, have earned the first GRAS approval, and their celebrated organic Oryzatein ® brown rice protein ingredient is patent - pending.

The study comes on the heels of a 2013 clinical trial that showed rice protein paralleled whey protein in its ability to build muscle and improve strength and power for the first time.

In 2011, the Cochrane Collaboration, a nonprofit independent research organization, analyzed the results of 15 randomized clinical trials that had evaluated whether omega - 3 — fortified infant formulas, fed to full - term babies for up to the first year of life, provide developmental benefits compared with nonfortified infant formulas.

«This double - blind RCT [randomized clinical trial] found no significant effect of pasteurized donor milk during the first 10 days of life for preventing serious infections, NEC and all - cause mortality in premature neonates.

Scientists are seeking the Food and Drug Administration's blessing for an unprecedented clinical trial — the first test of a drug to specifically target the process of human aging.

The phase 1 clinical trial is the first to test the functional replacement of the mutated gene responsible for SMA1.

The 21 - patient study, sponsored by the nonprofit Multidisciplinary Association for Psychedelic Studies (MAPS), launched in 2004 as the first U.S. clinical trial of a psychedelic drug in 35 years.

Ishii notes that if the clinical trial begins as planned, it would be the latest in a series of firsts for China in the field of CRISPR gene editing, including the first CRISPR - edited human embryos, and the first CRISPR - edited monkeys.

The first stage of clinical trials for at least one potential vaccine candidate is slated to begin in September, according to Fauci.

In this new study and for the first time, scientists used functional magnetic resonance imaging (fMRI) combined with a standard clinical trial design to derive an unbiased brain - based neurological marker to predict analgesia associated with placebo treatment in patients with chronic knee osteoarthritis pain.

«These are optimistic results for one of the first targeted therapies for cancer stem cells,» says Antonio Jimeno, MD, PhD, investigator at the CU Cancer Center, director of the university's Cancer Stem Cell - Directed Clinical Trials Program, and principal investigator of the clinical trial at the CU Cancer CentClinical Trials Program, and principal investigator of the clinical trial at the CU Cancer Centclinical trial at the CU Cancer Center site.

Researchers are designing the first clinical trials of stem cell treatments for fetuses afflicted with rare bone and blood diseases.

In a randomized, controlled clinical trial — the first of its kind — a multi-institution research team reports that daptomycin, part of a new class of antibiotics currently approved only for use in adults, is effective and well - tolerated in children.

First, the team analyzed past clinical trials for any signals that the drugs increased cancer risk; nothing popped up.

«While randomized clinical trials are needed to test whether this is a causal relationship, these findings indicate doctors should consider using or re-starting ACEIs and ARBs as first - line blood pressure medications for patients undergoing peritoneal dialysis,» said Jenny I. Shen, MD, an LA BioMed researcher and corresponding author of the study.

With proof of efficacy now published in monkeys and rabbits, preparations are being made for the first clinical trial in humans.

In March last year, the FDA approved Perin's request to conduct the country's first advanced, randomized, double - blind clinical trial of stem cells for heart failure.

Phase I / II clinical trial results reported at the American Society for Clinical Oncology (ASCO) Annual Meeting 2015 show promising results for investigational drug brigatinib against ALK + non-small cell lung cancer (NSCLC), with 58 of 78 ALK + patients responding to treatment, including 50 of 70 patients who had progressed after previous treatment with crizotinib, the first licensed ALK inclinical trial results reported at the American Society for Clinical Oncology (ASCO) Annual Meeting 2015 show promising results for investigational drug brigatinib against ALK + non-small cell lung cancer (NSCLC), with 58 of 78 ALK + patients responding to treatment, including 50 of 70 patients who had progressed after previous treatment with crizotinib, the first licensed ALK inClinical Oncology (ASCO) Annual Meeting 2015 show promising results for investigational drug brigatinib against ALK + non-small cell lung cancer (NSCLC), with 58 of 78 ALK + patients responding to treatment, including 50 of 70 patients who had progressed after previous treatment with crizotinib, the first licensed ALK inhibitor.

In the next year or so, Coyle expects the first clinical trials from CTIs to start, with three to five candidate proteins identified for trials each year, starting in 2013.

To evaluate whether the experimental treatment is safe and whether it might be able to reduce frailty, Maharaj plans to run a battery of baseline testing on each clinical trial participant before they get their first infusion of young plasma and then monitor their changes for two years: That means cognitive exams, questionnaires about their quality of life and their indicators of frailty, and tests to measure biomarkers he believes are linked with aging, such as telomere lengths and DNA methylation.

This study was the first major Alzheimer's clinical trial to require molecular evidence of amyloid deposition in the brain for enrollment.

Dr. Sparano continued: «This is the first prospectively conducted clinical trial evaluating this assay — or any multigene expression assay for that matter — in which patients with early stage breast cancer were uniformly treated based on their assay results.

Since CGP3466B has already been tested in phase II clinical trials to (unsuccessfully) treat Parkinson's disease and ALS, it is known to be safe for humans, but the researchers caution that many more years of studies are needed to definitively show whether it is effective for preventing cocaine damage, first in mice, then in humans.

The procedures have been successfully trialled in monkeys and if the techniques are approved for use in the UK, the regulations will be in place for clinical trials in people — a world first.

A clinical trial in the Republic of Korea for patients with degenerative eye diseases is the first to test the safety of an embryonic stem cell therapy for people of Asian descent.

«First - line immunotherapy treatment can improve survival for subset of lung cancer patients: Results of phase III global clinical trial show that 75 percent of stage IV lung cancer patients with both complex tumor mutations and PDL - 1 positive status respond to nivolumab.»

On the basis of the results, insurers agreed to pay for the drug in six more Dutch patients, and Vertex is following up with the first clinical trial of ivacaftor in CF patients with rare mutations.

Work done so far suggests that the technique — a modified form of IVF — is safe enough to try in clinical trials, the HFEA panel said, as long as several extra experiments are carried out first and children born as a result of the technique are followed up for an extensive period.

The latest study builds off of work Kawai and his colleagues began fourteen years ago, when they launched the first clinical trial that attempted to use bone marrow to induce immune tolerance for kidney recipients, to avoid the sometimes dangerous side effects of life - long immosuppressive therapy.

As for whether we should, today, be equipping soldiers with Tetris games to play immediately after battle, Holmes told LiveScience, «Not until we do clinical trials first.»

Studies are now open to recruit patients with metastatic breast cancer across Europe — these studies will first extend the analysis performed here to many more patients, but the ultimate goal is to build a platform for identifying an appropriate clinical trial of new treatments for each patient with metastatic breast cancer.

In collaboration with the Parker Institute for Cancer Immunotherapy (PICI), Wargo's team is developing the first immunotherapy - microbiome clinical trial, with a goal of launching it later this year.

This was the situation for the 14 arm amputees who took part in the first clinical trial of a new treatment, invented by Chalmers researcher Max Ortiz Catalan, and further developed with his multidisciplinary team in the past years.

Kosten recently completed the first placebo - controlled clinical trial for a cocaine addiction vaccine.

In a particularly dramatic demonstration at the Stanford site of the pilot clinical trial, a woman identified as «T6,» who is diagnosed with amyotrophic lateral sclerosis, was able to use BrainGate for six sessions of a few hours each over the course of 42 days without any interruptions for explicit recalibration after the decoder was initialized on the first day.

«Randomized Controlled Pilot Trial of Mindfulness - based Stress Reduction for Breast and Colorectal Cancer Survivors: Effects on Cancer - related Cognitive Impairment,» published online in advance of print in the Journal of Cancer Survivorship, is the first randomized clinical trial to evaluate the effects of mindfulness - based stress reduction, known as MBSR, on fatigued breast and colorectal cancer survivors, the majority of whom had been treated with chemotheTrial of Mindfulness - based Stress Reduction for Breast and Colorectal Cancer Survivors: Effects on Cancer - related Cognitive Impairment,» published online in advance of print in the Journal of Cancer Survivorship, is the first randomized clinical trial to evaluate the effects of mindfulness - based stress reduction, known as MBSR, on fatigued breast and colorectal cancer survivors, the majority of whom had been treated with chemothetrial to evaluate the effects of mindfulness - based stress reduction, known as MBSR, on fatigued breast and colorectal cancer survivors, the majority of whom had been treated with chemotherapy.

The Cardiothoracic Surgical Trials Network (CTSN) is reporting results for the first time from a clinical trial of patients who have a complication of coronary heart disease known as moderate ischemic mitral regurgitation (IMR).

«This double - blind RCT [randomized clinical trial] found no significant effect of pasteurized donor milk during the first 10 days of life for preventing serious infections, NEC and all - cause mortality in premature neonates.

If you're a medic who has completed junior training and a career in clinical research appeals to you more than general medicine, a useful first step would be to apply for clinical research jobs in a phase 1 trial at a research hospital.

NYU Langone Medical Center last month became the first hospital outside of a clinical trial site to implant a pacemaker - like device in the brain that may be a game - changer for patients with epilepsy.

The Wikipedia page also linked to stories about twin 5 - year - old girls who in 2009 had become the first Americans to fight NPC with an experimental treatment called cyclodextrin — but only after their parents had spent years pressing for «compassionate use» of the investigational drug outside of a clinical trial.

In a small, phase I clinical trial, Johns Hopkins Kimmel Cancer Center researchers say they show for the first time that the experimental drug guadecitabine (SGI - 110) is safe in combination with the chemotherapy drug irinotecan and may overcome resistance to irinotecan in patients with metastatic colorectal cancer.