Sentences with phrase «first clinical trial with»

Turnstone's first clinical trial with MG1 - MAGEA3, which is still ongoing, is testing the agent as a monotherapy in NSCLC, as well as in breast and esophageal cancers.

In 2003, VIRxSYS began the first clinical trial with a lentiviral vector.

The first clinical trial with HB - 201 targeting human papilloma virus - induced head and neck cancer is currently being prepared.

CVC researchers, including Elke Jaeger, Julia Karbach, Danila Valmori, Maha Ayyoub, Gerd Ritter, Dirk Jaeger, Eric Hoffman, Linda Pan, Lloyd J. Old, and Alex Knuth report on the first clinical trial with virus - encoded NY - ESO - 1 in a prime - boost setting.

First clinical trials with a Sclerostin - inhibiting antibody developed by the companies Amgen and UCB showed promising results in that the bone mass of participants suffering from osteoporosis increased.

On the other hand, first clinical trials with drugs designed to target cancer stem cells are now under way, so far yielding moderately positive results.

Not exact matches

In a research and strategy update, Novo said it will initiate a phase 3 clinical trial program with once - weekly subcutaneous semaglutide in obesity in the first half of 2018.

The group's first clinical trial, undertaken with Thrive Global, the behavioral change and wellness company founded by Brainstorm Health co-chair Arianna Huffington, begins in May.

At first he denied the charges against him, but after the Doctor charged with tipping him off about a death in a clinical drug trial plead guilty, he changed heart.

In a research and strategy update, Novo said it planned to start a final phase 3 clinical trial program with once - weekly subcutaneous semaglutide in obesity in the first half of 2018.

While this is not really a surprise, since similar research and trials with wounds on people has shown the healing benefits of using medical grade manuka honey, this is the first time a clinical trial has been done on horses.

«We chose to use Axiom Foods» Oryzatein ® ingredient,» said CEO of Growing Naturals, David Janow, «because it is the only 90 % brown rice protein isolate that is made with a proprietary enzyme fractioning method and was shown in a clinical trial for the first time to equal animal - based whey protein in building and maintaining muscle.»

Before the sack, Richardson's performance against Clowney is an offer any NFL GM would spend first - round money on: when applied on roughly one - third of called offensive plays in a single game, Tiny Richardson can nullify a premier pass - rushing defensive end with single coverage with a 95.4 percent success rate in clinical trials.

In 2011, the Cochrane Collaboration, a nonprofit independent research organization, analyzed the results of 15 randomized clinical trials that had evaluated whether omega - 3 — fortified infant formulas, fed to full - term babies for up to the first year of life, provide developmental benefits compared with nonfortified infant formulas.

Impact of a strategy to prevent the introduction of non-breast milk and complementary foods during the first 6 months of life: a randomized clinical trial with adolescent mothers and grandmothers

Influence of counseling sessions on the prevalence of breastfeeding in the first year of life: a randomized clinical trial with adolescent mothers and grandmothers

Nusinersen, approved by the U.S. Food and Drug Administration in December 2016, became the first drug approved to treat spinal muscular atrophy, with several other experimental drugs still in clinical trials.

He now is a co-investigator in the first randomized clinical trial comparing proton therapy with more conventional radiation — something he acknowledges should have happened before so much use.

«First clinical trial on HER -2-negative breast cancer with nintedanib shows promising results.»

The TOPCAT trial is the first randomized, double - blind trial to assess the effect of spironolactone on clinical outcomes in these patients with heart failure and preserved ejection fraction.

In this new study and for the first time, scientists used functional magnetic resonance imaging (fMRI) combined with a standard clinical trial design to derive an unbiased brain - based neurological marker to predict analgesia associated with placebo treatment in patients with chronic knee osteoarthritis pain.

The first clinical trial of a drug intended to delay the onset of symptoms of Huntington disease (HD) reveals that high - dose treatment with the nutritional supplement creatine was safe and well tolerated by most study participants.

Researchers are designing the first clinical trials of stem cell treatments for fetuses afflicted with rare bone and blood diseases.

We were the first to put up a clinical trial registry with all our data on a website.

In March, researchers, in collaboration with the pharmaceutical company Ultragenyx, completed the first part of a Phase III clinical trial in adults with XLH — the final test of a drug before federal approval.

The first controlled, but controversial and small, clinical trial of giving young blood to people with dementia has reported that the procedure appears safe.

Once we have demonstrated the proof of concept in animal studies, the next goal will be to work towards the first human clinical trial with graphene devices during intraoperative mapping of the brain.

In my experience, this marks both the first clinical trial of an approved drug with an effect on survival in advanced melanoma in the adjuvant setting, and, in this same setting, the first to study an immune checkpoint inhibitor in the adjuvant setting.

With proof of efficacy now published in monkeys and rabbits, preparations are being made for the first clinical trial in humans.

«This clinical trial is the first time we can show with hard data that ablation is saving more lives than arrhythmia medications,» said Marrouche.

Phase I / II clinical trial results reported at the American Society for Clinical Oncology (ASCO) Annual Meeting 2015 show promising results for investigational drug brigatinib against ALK + non-small cell lung cancer (NSCLC), with 58 of 78 ALK + patients responding to treatment, including 50 of 70 patients who had progressed after previous treatment with crizotinib, the first licensed ALK inclinical trial results reported at the American Society for Clinical Oncology (ASCO) Annual Meeting 2015 show promising results for investigational drug brigatinib against ALK + non-small cell lung cancer (NSCLC), with 58 of 78 ALK + patients responding to treatment, including 50 of 70 patients who had progressed after previous treatment with crizotinib, the first licensed ALK inClinical Oncology (ASCO) Annual Meeting 2015 show promising results for investigational drug brigatinib against ALK + non-small cell lung cancer (NSCLC), with 58 of 78 ALK + patients responding to treatment, including 50 of 70 patients who had progressed after previous treatment with crizotinib, the first licensed ALK inhibitor.

In the next year or so, Coyle expects the first clinical trials from CTIs to start, with three to five candidate proteins identified for trials each year, starting in 2013.

In 1996, when RMP - 7 was first used on brain cancer patients in a Phase 1 clinical trial at UCLA, it was found to be safe, with virtually no side effects.

While other randomized clinical trials have evaluated the effects of varying weight loss in people with obesity, this is thought to be the first time a trial has separated weight loss outcomes in people who achieved a 5 percent weight loss from those who achieved a 10 percent or greater weight loss.

«It's the first clinical trial of a drug with this action in patients with cancer,» says Peter Lewis, the director of research and development.

To evaluate whether the experimental treatment is safe and whether it might be able to reduce frailty, Maharaj plans to run a battery of baseline testing on each clinical trial participant before they get their first infusion of young plasma and then monitor their changes for two years: That means cognitive exams, questionnaires about their quality of life and their indicators of frailty, and tests to measure biomarkers he believes are linked with aging, such as telomere lengths and DNA methylation.

Dr. Sparano continued: «This is the first prospectively conducted clinical trial evaluating this assay — or any multigene expression assay for that matter — in which patients with early stage breast cancer were uniformly treated based on their assay results.

The two drug combination «reveals the possibilities of combining an immune signaling molecule with taking the brakes off at the same time,» said F. Stephen Hodi, MD, first author on the clinical trial report.

In its first clinical trial, a breakthrough antibody therapy produced at least partial remissions in a third of patients with multiple myeloma who had exhausted multiple prior treatments, investigators at Dana - Farber Cancer Institute and other organizations report today online in the New England Journal of Medicine.

A clinical trial in the Republic of Korea for patients with degenerative eye diseases is the first to test the safety of an embryonic stem cell therapy for people of Asian descent.

A panel of top science administrators and stem cell scientists met on Friday with Davide Vannoni, the president of an Italian foundation providing highly controversial stem cell treatments, in a first effort to hash out the details of a government - sponsored clinical trial of the therapy.

«First - line immunotherapy treatment can improve survival for subset of lung cancer patients: Results of phase III global clinical trial show that 75 percent of stage IV lung cancer patients with both complex tumor mutations and PDL - 1 positive status respond to nivolumab.»

On the basis of the results, insurers agreed to pay for the drug in six more Dutch patients, and Vertex is following up with the first clinical trial of ivacaftor in CF patients with rare mutations.

As for whether we should, today, be equipping soldiers with Tetris games to play immediately after battle, Holmes told LiveScience, «Not until we do clinical trials first.»

Studies are now open to recruit patients with metastatic breast cancer across Europe — these studies will first extend the analysis performed here to many more patients, but the ultimate goal is to build a platform for identifying an appropriate clinical trial of new treatments for each patient with metastatic breast cancer.

In collaboration with the Parker Institute for Cancer Immunotherapy (PICI), Wargo's team is developing the first immunotherapy - microbiome clinical trial, with a goal of launching it later this year.

This was the situation for the 14 arm amputees who took part in the first clinical trial of a new treatment, invented by Chalmers researcher Max Ortiz Catalan, and further developed with his multidisciplinary team in the past years.

In a particularly dramatic demonstration at the Stanford site of the pilot clinical trial, a woman identified as «T6,» who is diagnosed with amyotrophic lateral sclerosis, was able to use BrainGate for six sessions of a few hours each over the course of 42 days without any interruptions for explicit recalibration after the decoder was initialized on the first day.

«Randomized Controlled Pilot Trial of Mindfulness - based Stress Reduction for Breast and Colorectal Cancer Survivors: Effects on Cancer - related Cognitive Impairment,» published online in advance of print in the Journal of Cancer Survivorship, is the first randomized clinical trial to evaluate the effects of mindfulness - based stress reduction, known as MBSR, on fatigued breast and colorectal cancer survivors, the majority of whom had been treated with chemotheTrial of Mindfulness - based Stress Reduction for Breast and Colorectal Cancer Survivors: Effects on Cancer - related Cognitive Impairment,» published online in advance of print in the Journal of Cancer Survivorship, is the first randomized clinical trial to evaluate the effects of mindfulness - based stress reduction, known as MBSR, on fatigued breast and colorectal cancer survivors, the majority of whom had been treated with chemothetrial to evaluate the effects of mindfulness - based stress reduction, known as MBSR, on fatigued breast and colorectal cancer survivors, the majority of whom had been treated with chemotherapy.

This is the first randomised clinical trial using as a research tool a high - fidelity simulation mannequin with a physiological response as a human being, a medical vehicle and volunteering healthcare practitioners from the Alicante Health Emergency Service (SES).