Sentences with phrase «first drug designed»
It was the first drug designed to inhibit new vessel growth (angiogenesis), and was approved by the FDA in 2004 for treating colorectal cancers — which typically boost angiogenesis to keep themselves well supplied with oxygen and nutrients.
https://www.sciencedaily.com/ Not exact matches
The system — the first time ever that a state has put itself in charge of the production and distribution of marijuana — is designed to undercut lucrative and illegal drugs trafficking.
Langer, an MIT Institute Professor with some 750 patents issued or pending worldwide, was one of the first people to apply chemical engineering methods to medical applications, pioneering the use of specially designed polymers for targeted drug delivery and tissue regeneration.
Late last week, the Food and Drug Administration gave its stamp of approval to the marketing of the world's first device designed to help diagnose ADHD — a disorder that plagues some 6.4 million children — by scanning a child's brain waves.
«We could apply the strategy used in this study to quickly identify and design small molecule drugs for other RNA - associated diseases,» explained study first author Sai Velagapudi, a research associate in the Disney lab.
But first, Stegh and colleagues want to hone the particle design and to investigate treatments that combine miR - 182 with established chemotherapy drugs in mouse models.
This is the first time this technique has been used to design a drug.
Dr. Melnick developed the first BCL6 inhibitors nine years ago, and has continued to improve upon the design of these drugs so they could be used to treat cancer patients.
UCLA chemists and molecular biologists have for the first time used a «structure - based» approach to drug design to identify compounds with the potential to delay or treat Alzheimer's disease, and possibly Parkinson's, Lou Gehrig's disease and other degenerative disorders.
The researchers targeted mTOR with an experimental drug based on a prototype first designed by Shokat, a chemist and an expert in designing molecules to target this type of protein, called a kinase.
An experimental drug designed to help regulate the blood's iron supply shows promise as a viable first treatment for anemia of inflammation, according to results from the first human study of the treatment published online today in Blood, the Journal of the American Society of Hematology
The first drug to treat calcification of heart valves may be one originally designed for rheumatoid arthritis.
A Georgetown University professor published in the online journal PLOS ONE the first study explaining why drugs designed to fight off malaria stop working in some people with the disease.
These are the first ever drugs specifically designed to prevent the crippling headaches before they start, and they could be approved by the U.S. Food and Drug Administration next year.
«Identifying new pathways that can be targeted for drug design is an important step forward in improving the treatment of depressive disorders,» said Sarah Brooker, the first author and an M.D. / Ph.D student at Northwestern University Feinberg School of Medicine.
«This is the first example of taking a genetic sequence and designing a drug candidate that works effectively in an animal model against triple negative breast cancer,» said TSRI Professor Matthew Disney.
In a development that could lead to a new generation of drugs to precisely treat a range of diseases, scientists from the Florida campus of The Scripps Research Institute (TSRI) have for the first time designed a drug candidate that decreases the growth of tumor cells in animal models in one of the hardest to treat cancers — triple negative breast cancer.
Dr Emma Smith, senior science communications officer at Cancer Research UK, said: «Revealing the molecule's detailed shape could be the first step towards designing more precise drugs to block it.
In 2015, Forbes reported that Yancopoulos became the first pharmaceutical research chief to become a billionaire, as a result of his work at Regeneron, which includes inventing four approved drugs and designing the technology to assist in making more.
«This is the first instance I am aware of where an academic drug discovery group moved a molecule designed to hopefully treat a chronic brain disorder all the way from early discovery to human trials without there being, at some point along the way, a pharmaceutical partner,» said P. Jeffrey Conn, Ph.D., Lee E. Limbird Professor of Pharmacology in the Vanderbilt University School of Medicine and director of the Vanderbilt Center for Neuroscience Drug Discovery (VCNdrug discovery group moved a molecule designed to hopefully treat a chronic brain disorder all the way from early discovery to human trials without there being, at some point along the way, a pharmaceutical partner,» said P. Jeffrey Conn, Ph.D., Lee E. Limbird Professor of Pharmacology in the Vanderbilt University School of Medicine and director of the Vanderbilt Center for Neuroscience Drug Discovery (VCNDrug Discovery (VCNDD).
Identifying the effects of faulty genes is a vital first step to being able to design drugs that could best help people living with the condition.
(WASHINGTON, August, 27, 2014)-- An experimental drug designed to help regulate the blood's iron supply shows promise as a viable first treatment for anemia of inflammation, according to results from the first human study of the treatment published online today in Blood, the Journal of the American Society of Hematology (ASH).
On the other hand, first clinical trials with drugs designed to target cancer stem cells are now under way, so far yielding moderately positive results.
MD Anderson's Institute for Applied Cancer Science (IACS) initiated the first clinical study of a novel drug designed to starve cancer cells, IACS - 10759.
This is the first time a novel compound specifically designed to treat SMA has reached this stage in drug development.
Typical nanoparticle designs don't allow for scaling, since they call for building a nanoparticle first and then encapsulating the drug molecules within it, or chemically attaching the molecules to the nanoparticle.
«It provides the first structural basis for the sensitivity of anesthetics, a crucial tool for understanding how these drugs work and ultimately designing better ones.»
And this «futility trial» design - the first of its kind in HD - is likely to be a really useful way of choosing the most promising drugs to test in large studies.
The drug, called STX209 or arbaclofen, is one of the first designed to treat the molecular changes in the brain caused by fragile X syndrome.
In a discovery that may help scientists design new cancer drugs, Howard Hughes Medical Institute researchers have provided scientists with the first definitive look at how the catalytic center of the...
A research scientist becomes the world's first pregnant man in order to test a drug he and a colleague have designed for expectant women.
The first drug in its class to be approved for veterinary use, Apoquel is specifically designed to address the source of the itch, providing fast - acting relief and minimal side effects.
Physiomesh Flexible Composite Mesh is a type of synthetic hernia mesh designed to support the surrounding tissue after a hernia repair surgery first cleared by the United States Food and Drug Administration (FDA) in April of 2010 and withdrawn from the market in May of 2016 after medical professionals expressed concern over results from a clinical trial.
D.A.T.A., Drug Alcohol Traffic Awareness, but also referred to as the First time Driver's course is a 4 - hour program designed to teach those wanting to obtain their driver's license in the cities of Callaway, Springfield, Lynn Haven, Panama City, and Lake City, the rules and regulations of the road, safety driving techniques, alcohol and substance abuse and the effect they have on your driving abilities, and more.
The first step in designing and implementing a drug education program is the estab - lishment of a program - level drug awareness task force involving parents, teachers, and administrators.