Sentences with phrase «first embryonic»

The VC - 01 product candidate is the first embryonic stem cell - derived islet replacement therapy to reach clinical testing and is currently being evaluated in patients with T1D who have minimal to no insulin - producing beta cell function.

Then there are stem cells, which tantalize with their myriad possibilities: allowing diabetics to throw away their insulin, growing healthy cardiac tissue after a heart attack, restoring function to people with spinal cord injury (for which the Food and Drug Administration just approved the first embryonic stem cell trial).

CARS microscopy also confirmed the gradual increase of the size of lipid containing structures during oogenesis (Figs. 5A and 5B), the sudden re-localization of these structures to the periphery of the dividing nucleus in the first embryonic division (Fig. 5E), and the propagation of this phenotype, although with gradually diminishing appearance, throughout embryonic development (Figs. 5F and 5H).

«When we look back in 25 years, putting the first embryonic stem cells into humans will prove as momentous as man's first step on the moon.»

In February 2004 Hwang and his research group reported the first embryonic stem cell line derived from a cloned human embryo.

The world's first embryonic stem cell bank should be up and running within a year.

«First embryonic stem cell therapy safety trial in Asian patients.»

These are the first embryonic remains of sauropods, and they settle the controversy over whether the ponderous, long - necked, long - tailed dinosaurs produced live births.

Not exact matches

First, the authors focus on a protein, the transcription factor nanog, and assert that because it «does not block the early embryonic development of the zygote,» therefore ANT - OAR «produces a crippled embryo.»

Because the possibility of «twinning» exists for that long in the first stages of embryonic development, one could argue that no individual human being can yet be present - and that, hence, experimentation should be permitted.

The first page of Larsen's Human Embryology states that, `... [W] e begin our description of the developing human with the formation and differentiation of the male and female sex cells or gametes [sperm and egg], which will unite at fertilisation to initiate the embryonic development of a new individual».

Her work involves mapping the first six days of human embryonic life.

While scientists have previously had success in 3D printing a range of human stem cell cultures developed from bone marrow or skin cells, a team from Scotland's Heriot - Watt University claims to be the first to print the more delicate, yet more flexible, human embryonic stem cells (hESCs).

(CNN)- The White House meant no disrespect toward Nancy Reagan when it failed to invite the former first lady and vigorous supporter of embryonic stem cell research to a bill signing ceremony on the subject, press secretary Robert Gibbs said Tuesday.

«It is important to bear in mind that the first phase will be embryonic,» said Li Shuo, senior global policy adviser for Greenpeace East Asia, who has been briefed on some details of the coming plan.

A recent federal court injunction based on a congressional budget amendment passed years before the first human embryonic stem cells were isolated has thrown many of the field's ongoing projects into limbo

To turn one cell into another you usually need to first rewind them into embryonic - like stem cells.

Trials of cells made from human embryonic stem cells are also poised to begin in people with type 1 diabetes and heart failure, the first time embryonic stem cells have been used in the treatment of major lethal diseases.

Geron was bigger and better funded than ACT, and it was the first company to be approved by the US Food and Drug Administration (FDA) to test a therapy in humans based on embryonic stem (ES) cells.

For the first time, specialised cells have been reprogrammed into the equivalent of embryonic stem cells without using genes that might trigger cancer.

Setton and her group backtracked, devising a series of steps to first produce one of the earliest - forming embryonic structures, the notochord.

Base oxidation regulates gene activity In cooperation with colleagues at LMU, as well as researchers based in Berlin, Basel and Utrecht, Carell and his group have now shown, for the first time, that a standard base other than cytosine is also modified in embryonic stem cells of mice.

«We've figured out for the first time how to produce these cells from human embryonic stem cells literally by the billions and billions,» Lanza says.

By observing how the genes changed during the course of embryonic development, scientists could track the emergence of a novel physical trait, the first step toward the creation of a new species.

Groups of red and green labelled embryonic cells in a zebrafish during their first migration in gastrulation.

Meet GloFish, the world's first genetically engineered pets — tropical zebra danios that fluoresce red thanks to a gene scientists transplanted into their embryonic DNA.

In the United Kingdom, research on embryonic stem cells is legal in the first 2 weeks of their development.

Embryonic - like stem cells have previously been discovered in amniotic fluid and in the umbilical cord, but this is the first time they have been discovered in an adult.

For this study, Guttridge, first author David J. Wang, who developed many of the study's concepts, and their colleagues monitored NF - kB activity during tumor development using mouse embryonic fibroblasts and two mouse models.

Although British researchers had discovered embryonic stem cells in laboratory animals in 1981, it wasn't until 1998 that a Wisconsin team announced it had isolated stem cells from human embryos for the first time.

Eighteen adults with severe eye disease who were among the first people to receive transplants created from human embryonic stem cells (hESCs) continue to have no apparent complications with the introduced cells after an average of nearly 2 years, according to the latest status report on their health.

Then, a team led by Robert Lanza, the chief scientific officer of Advanced Cell Technology Inc. in Marlborough, Massachusetts, and his colleagues published the first results ever of a clinical trial using human embryonic stem cells.

In the past year, the South Korean Food and Drug Administration (FDA) has approved the world's first three stem - cell treatments — Hearticellgram - AMI, Cupistem and Cartistem — which followed on the heels of clinical tests for human embryonic stem - cell therapies approved in 2010, according to the health ministry.

A person with spinal injuries today went down in history as the first to receive a treatment derived from human embryonic stem cells (hESCs).

In May 2013, Mitalipov was the first scientist in the world to demonstrate the successful use of somatic cell nuclear transfer, or SCNT, to produce human embryonic stem cells from an individual's skin cell.

The immediate payoff was a commercialization deal in age - related macular degeneration in which Pfizer became the first big pharma company to make a move into the use of embryonic stem cells as the basis for a tissue regeneration therapy.

Others have tracked the first few hours of the embryonic development of sea urchins and other organisms with the goal of seeing how various transcription factors alter gene expression over time.

As it happens, moas were also the subject of Cooper's first foray into ancient DNA: He spent a year in the late 1980s working on them at the University of California at Berkeley, when paleogenetics was still an embryonic field.

We take a human embryonic stem cell, and we inject it into a monkey blastocyst [the first 130 or so cells in a newly formed embryo].

Mouse embryos: Scientists first found embryonic stem cells in mice in the 1970s, but an understanding of the critical role they play in cell differentiation only emerged years later.

Starting in the mid-2000s, Yoshiki Sasai's team at the RIKEN Center for Developmental Biology in Kobe, Japan, demonstrated how to grow brainlike structures using embryonic stem cells, first from mice and then humans.

The scientists first compared mouse megakaryocyte cells created from embryonic stem cells engineered to lack p45 - Nfe2 with normal megakaryocytes.

Facial asymmetries and minor physical anomalies begin to appear early in embryonic development, mainly the first trimester of pregnancy, and can be a sign of instability during this growth.

ACT, which has almost gone under several times in recent years, may now be on the verge of conducting the nation's first trial of an embryonic stem cell therapy, says Chief Scientific Officer Robert Lanza.

A clinical trial in the Republic of Korea for patients with degenerative eye diseases is the first to test the safety of an embryonic stem cell therapy for people of Asian descent.

In the U.S., as well as in Germany and the UK, first results with adult stem cells suggest that they are at least equivalent to embryonic stem cells.

But after learning that work by South Korean scientist Woo Suk Hwang had been faked, the journal Science retracted Hwang's landmark papers from 2004 and 2005, which reported the first human embryonic stem cells from cloned embryos.

The first known pterosaur egg reveals a well - developed embryonic skeleton, com - plete with wing membranes and skin impressions.

The work was led by Dan S. Kaufman, a hematologist, and James A. Thomson, the first scientist to grow human embryonic stem cells in culture.

Around the same time, Yoshiki Sasai of the RIKEN Center for Developmental Biology in Kobe, Japan, cultured the first brain organoids, starting not with adult stem cells but with embryonic stem cells.