The VC - 01 product candidate is
the first embryonic stem cell - derived islet replacement therapy to reach clinical testing and is currently being evaluated in patients with T1D who have minimal to no insulin - producing beta cell function.
Then there are stem cells, which tantalize with their myriad possibilities: allowing diabetics to throw away their insulin, growing healthy cardiac tissue after a heart attack, restoring function to people with spinal cord injury (for which the Food and Drug Administration just approved
the first embryonic stem cell trial).
In February 2004 Hwang and his research group reported
the first embryonic stem cell line derived from a cloned human embryo.
The world's
first embryonic stem cell bank should be up and running within a year.
«
First embryonic stem cell therapy safety trial in Asian patients.»
«When we look back in 25 years, putting
the first embryonic stem cells into humans will prove as momentous as man's first step on the moon.»
Not exact matches
While scientists have previously had success in 3D printing a range of human
stem cell cultures developed from bone marrow or skin
cells, a team from Scotland's Heriot - Watt University claims to be the
first to print the more delicate, yet more flexible, human
embryonic stem cells (hESCs).
(CNN)- The White House meant no disrespect toward Nancy Reagan when it failed to invite the former
first lady and vigorous supporter of
embryonic stem cell research to a bill signing ceremony on the subject, press secretary Robert Gibbs said Tuesday.
A recent federal court injunction based on a congressional budget amendment passed years before the
first human
embryonic stem cells were isolated has thrown many of the field's ongoing projects into limbo
To turn one
cell into another you usually need to
first rewind them into
embryonic - like
stem cells.
Trials of
cells made from human
embryonic stem cells are also poised to begin in people with type 1 diabetes and heart failure, the
first time
embryonic stem cells have been used in the treatment of major lethal diseases.
Geron was bigger and better funded than ACT, and it was the
first company to be approved by the US Food and Drug Administration (FDA) to test a therapy in humans based on
embryonic stem (ES)
cells.
For the
first time, specialised
cells have been reprogrammed into the equivalent of
embryonic stem cells without using genes that might trigger cancer.
Base oxidation regulates gene activity In cooperation with colleagues at LMU, as well as researchers based in Berlin, Basel and Utrecht, Carell and his group have now shown, for the
first time, that a standard base other than cytosine is also modified in
embryonic stem cells of mice.
«We've figured out for the
first time how to produce these
cells from human
embryonic stem cells literally by the billions and billions,» Lanza says.
In the United Kingdom, research on
embryonic stem cells is legal in the
first 2 weeks of their development.
Embryonic - like
stem cells have previously been discovered in amniotic fluid and in the umbilical cord, but this is the
first time they have been discovered in an adult.
Although British researchers had discovered
embryonic stem cells in laboratory animals in 1981, it wasn't until 1998 that a Wisconsin team announced it had isolated
stem cells from human embryos for the
first time.
Eighteen adults with severe eye disease who were among the
first people to receive transplants created from human
embryonic stem cells (hESCs) continue to have no apparent complications with the introduced
cells after an average of nearly 2 years, according to the latest status report on their health.
Then, a team led by Robert Lanza, the chief scientific officer of Advanced
Cell Technology Inc. in Marlborough, Massachusetts, and his colleagues published the
first results ever of a clinical trial using human
embryonic stem cells.
In the past year, the South Korean Food and Drug Administration (FDA) has approved the world's
first three
stem -
cell treatments — Hearticellgram - AMI, Cupistem and Cartistem — which followed on the heels of clinical tests for human
embryonic stem -
cell therapies approved in 2010, according to the health ministry.
A person with spinal injuries today went down in history as the
first to receive a treatment derived from human
embryonic stem cells (hESCs).
In May 2013, Mitalipov was the
first scientist in the world to demonstrate the successful use of somatic
cell nuclear transfer, or SCNT, to produce human
embryonic stem cells from an individual's skin
cell.
The immediate payoff was a commercialization deal in age - related macular degeneration in which Pfizer became the
first big pharma company to make a move into the use of
embryonic stem cells as the basis for a tissue regeneration therapy.
We take a human
embryonic stem cell, and we inject it into a monkey blastocyst [the
first 130 or so
cells in a newly formed embryo].
Mouse embryos: Scientists
first found
embryonic stem cells in mice in the 1970s, but an understanding of the critical role they play in
cell differentiation only emerged years later.
Starting in the mid-2000s, Yoshiki Sasai's team at the RIKEN Center for Developmental Biology in Kobe, Japan, demonstrated how to grow brainlike structures using
embryonic stem cells,
first from mice and then humans.
The scientists
first compared mouse megakaryocyte
cells created from
embryonic stem cells engineered to lack p45 - Nfe2 with normal megakaryocytes.
ACT, which has almost gone under several times in recent years, may now be on the verge of conducting the nation's
first trial of an
embryonic stem cell therapy, says Chief Scientific Officer Robert Lanza.
A clinical trial in the Republic of Korea for patients with degenerative eye diseases is the
first to test the safety of an
embryonic stem cell therapy for people of Asian descent.
In the U.S., as well as in Germany and the UK,
first results with adult
stem cells suggest that they are at least equivalent to
embryonic stem cells.
But after learning that work by South Korean scientist Woo Suk Hwang had been faked, the journal Science retracted Hwang's landmark papers from 2004 and 2005, which reported the
first human
embryonic stem cells from cloned embryos.
The work was led by Dan S. Kaufman, a hematologist, and James A. Thomson, the
first scientist to grow human
embryonic stem cells in culture.
Around the same time, Yoshiki Sasai of the RIKEN Center for Developmental Biology in Kobe, Japan, cultured the
first brain organoids, starting not with adult
stem cells but with
embryonic stem cells.
In June Italian scientists announced the
first human
embryonic stem cells derived from parthenotes — embryo - like structures formed when an egg starts to divide on its own, with no sperm involved.
THE world's
first cloned human
embryonic stem cells (hESCs) are here, but they can't yet be used to grow tissues for transplant because they have an extra set of chromosomes.
The world's
first chimeric monkeys were created in a laboratory last year, and they offer surprising new insights into
embryonic stem cell therapy: One reason for often - poor treatment outcomes may be that we're using embryos that are, strangely, just too old.
In the decade since the
first human
embryonic stem cells were isolated, the science surrounding
stem cells has grown dramatically.
Amid all this, are you still trying to achieve your
first dream, harvesting
embryonic stem cells from human clones?
This Korean researcher racked up a series of important advances in
embryonic stem cell technology, including the
first lines of
cells from patients
This will mark the start of the
first clinical trial in China using human
embryonic stem (ES)
cells, and the
first one worldwide aimed at treating Parkinson's disease using ES
cells from fertilized embryos.
In 1983, Beddington set up her own lab at Oxford and became one of the
first scientists to demonstrate that
embryonic stem cells can give rise to any tissue found in a developed body.
A U.S. - based company has received permission to start Europe's
first clinical trial involving human
embryonic stem (hES)
cells.
UC announced yesterday that it is the
first research institution to seek to «intervene,» or become a party in the case, in which the government is appealing a lower court's ruling that National Institutes of Health (NIH) funding to study human
embryonic stem cells (hESCs) violates federal law.
The embryos, on average, had just 0.2 % of carried - over mitochondrial DNA (mtDNA), and the resulting
embryonic stem cells at
first harboured similarly minuscule levels.
Karim Nayernia of the University of Newcastle, UK, and his colleagues treated male
embryonic stem cells (ESCs) with a range of substances, which converted them
first into germline
stem cells and then into spermatogonial
stem cells.
The new finding brings a measure of closure to a story that
first rocked the science world in February 2004, when Hwang and colleagues at Seoul National University announced they had cloned a female donor's
cell by transferring its nucleus into one of her egg
cells stripped of its nucleus in a procedure known as somatic
cell nuclear transfer (SCNT), and harvested
embryonic stem cells from the resulting fusion.
An ambitious plan to map the genome's regulatory elements will focus
first on mouse
embryonic stem cells.
Other researchers had successfully used a similar process to turn skin
cells into
embryonic - like
cells called induced pluripotent
stem cells, and then grow those iPS
cells into nerve
cells, but Wernig's lab was the
first to convert skin
cells directly into nerve
cells without the intermediate iPS
cell step.
The next year, the
first human
embryonic -
stem -
cell paper came out.