In the decade since
the first human embryonic stem cells were isolated, the science surrounding stem cells has grown dramatically.
In June Italian scientists announced
the first human embryonic stem cells derived from parthenotes — embryo - like structures formed when an egg starts to divide on its own, with no sperm involved.
But after learning that work by South Korean scientist Woo Suk Hwang had been faked, the journal Science retracted Hwang's landmark papers from 2004 and 2005, which reported
the first human embryonic stem cells from cloned embryos.
A recent federal court injunction based on a congressional budget amendment passed years before
the first human embryonic stem cells were isolated has thrown many of the field's ongoing projects into limbo
Not exact matches
While scientists have previously had success in 3D printing a range of
human stem cell cultures developed from bone marrow or skin
cells, a team from Scotland's Heriot - Watt University claims to be the
first to print the more delicate, yet more flexible,
human embryonic stem cells (hESCs).
Trials of
cells made from
human embryonic stem cells are also poised to begin in people with type 1 diabetes and heart failure, the
first time
embryonic stem cells have been used in the treatment of major lethal diseases.
Geron was bigger and better funded than ACT, and it was the
first company to be approved by the US Food and Drug Administration (FDA) to test a therapy in
humans based on
embryonic stem (ES)
cells.
«We've figured out for the
first time how to produce these
cells from
human embryonic stem cells literally by the billions and billions,» Lanza says.
Although British researchers had discovered
embryonic stem cells in laboratory animals in 1981, it wasn't until 1998 that a Wisconsin team announced it had isolated
stem cells from
human embryos for the
first time.
Eighteen adults with severe eye disease who were among the
first people to receive transplants created from
human embryonic stem cells (hESCs) continue to have no apparent complications with the introduced
cells after an average of nearly 2 years, according to the latest status report on their health.
Then, a team led by Robert Lanza, the chief scientific officer of Advanced
Cell Technology Inc. in Marlborough, Massachusetts, and his colleagues published the
first results ever of a clinical trial using
human embryonic stem cells.
In the past year, the South Korean Food and Drug Administration (FDA) has approved the world's
first three
stem -
cell treatments — Hearticellgram - AMI, Cupistem and Cartistem — which followed on the heels of clinical tests for
human embryonic stem -
cell therapies approved in 2010, according to the health ministry.
A person with spinal injuries today went down in history as the
first to receive a treatment derived from
human embryonic stem cells (hESCs).
In May 2013, Mitalipov was the
first scientist in the world to demonstrate the successful use of somatic
cell nuclear transfer, or SCNT, to produce
human embryonic stem cells from an individual's skin
cell.
We take a
human embryonic stem cell, and we inject it into a monkey blastocyst [the
first 130 or so
cells in a newly formed embryo].
Starting in the mid-2000s, Yoshiki Sasai's team at the RIKEN Center for Developmental Biology in Kobe, Japan, demonstrated how to grow brainlike structures using
embryonic stem cells,
first from mice and then
humans.
The work was led by Dan S. Kaufman, a hematologist, and James A. Thomson, the
first scientist to grow
human embryonic stem cells in culture.
THE world's
first cloned
human embryonic stem cells (hESCs) are here, but they can't yet be used to grow tissues for transplant because they have an extra set of chromosomes.
Amid all this, are you still trying to achieve your
first dream, harvesting
embryonic stem cells from
human clones?
This will mark the start of the
first clinical trial in China using
human embryonic stem (ES)
cells, and the
first one worldwide aimed at treating Parkinson's disease using ES
cells from fertilized embryos.
In February 2004 Hwang and his research group reported the
first embryonic stem cell line derived from a cloned
human embryo.
A U.S. - based company has received permission to start Europe's
first clinical trial involving
human embryonic stem (hES)
cells.
UC announced yesterday that it is the
first research institution to seek to «intervene,» or become a party in the case, in which the government is appealing a lower court's ruling that National Institutes of Health (NIH) funding to study
human embryonic stem cells (hESCs) violates federal law.
The next year, the
first human embryonic -
stem -
cell paper came out.
It has taken more than five years of graft, but at long last approval has been given for the
first clinical trial using
human embryonic stem cells (hESCs).
In the
first published results from a clinical trial using
human embryonic stem cells, two legally blind patients who received an injection of hESC - derived
cells in one eye have experienced no harmful side effects and appear to have slightly better vision.
Skin
cells reprogrammed to act like
embryonic stem cells — a breakthrough
first reported in
human cells 2 weeks ago — are already showing promise as a therapeutic agent.
One team in Japan, and another in the US, have independently shown it is possible to produce
embryonic - like
stem cells directly from a patient's own skin
cells without having to create and destroy a cloned
human embryo
first.
According to a new analysis, the
cell line they created represented the
first example of parthenogenetic
human embryonic stem (ES)
cells.
«When we look back in 25 years, putting the
first embryonic stem cells into
humans will prove as momentous as man's
first step on the moon.»
Expanding from their previous studies with mice, the researchers
first established that under specific conditions, culturing
human embryonic stem cells with fibroblast growth factor 2 (FGF2) leads to neural differentiation particular to the midbrain / hindbrain region — the location of the cerebellum — within three weeks, and the expression of markers for the cerebellar plate neuroepithelium — the part of the developing nervous system specific for the cerebellum — within five.
Though Hwang Woo - suk, a South Korean scientist claimed to have created the
first human embryonic clone and derived a
stem -
cell line from it in 2004 his work was later shown to be fraudulent.
Geron became the
first company to start clinical trials of
embryonic stem cells in
humans, starting with a patient who had spinal cord injuries.
Keirstead's laboratory was the
first in the world to develop a method to restrict
human embryonic stem cells so they generate large amounts of only one
cell type in high purity.
For the
first time, through the use of
human embryonic stem cells (hES) sourced from pre-implantation diagnosis, researchers from Inserm's Institute for Stem Cell Therapy and Exploration of Monogenic Diseases (I - Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystro
stem cells (hES) sourced from pre-implantation diagnosis, researchers from Inserm's Institute for
Stem Cell Therapy and Exploration of Monogenic Diseases (I - Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystro
Stem Cell Therapy and Exploration of Monogenic Diseases (I -
Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystro
Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystrophy.
About 10 years ago, Zhang was the
first in the world to grow motor neurons from
human embryonic stem cells.
John Gearhart, one of the
first scientists to isolate, in 1998,
human embryonic stem cells, also downplayed the therapeutic value of
human cloning, saying «the more we learn about reprogramming, the more I think IPS will be the one of choice.»
Researchers at UCLA treat the
first patients in the second FDA - approved study evaluating a therapy made from
human embryonic stem cells.
That study found that since MSCRF
first began awarding grants in 2007, its pattern of giving shifted over the years from strongly favoring projects focusing on ethically contentious
human embryonic stem cell research (hESCR) to projects focusing on ethically non-contentious adult
stem cells and other non-
embryonic stem cell research.
After many delays, the
first FDA - approved experiment in people of a therapy made using
human embryonic stem cells began in October.
For the
first time since the linkurl: National Institutes of Health; http://www.nih.gov/ released its new guidelines for the derivation of
human embryonic stem cell (hESC) lines last summer, a line approved under the Bush administration has been recommended for inclusion into the growing federal registry of lines eligible for federal funding.
Researchers have treated the
first two patients in the second government - authorized attempt to evaluate a therapy created using
human embryonic stem cells in the United States.
University of Wisconsin scientist, James A. Thomson, who
first derived ESCs from embryos, has said «if
human embryonic stem cell research does not make you at least a little bit uncomfortable, you have not thought about it enough.»
Wicker, no political naïf, brought out the big rhetorical ammo, reminding the senators that it was Jamie Thomson, the University of Wisconsin scientist who
first reported isolating the
cells in 1998, who said: «If
human embryonic stem cell research does not make you at least a bit uncomfortable, you have not thought about it enough.»
Beginning in the 1990's, and throughout the
first years of the 21st century, perhaps no other political or social cause célèbre attracted as many celebrities as
human embryonic stem cell research (hESCR).
This was the position taken by then President Clinton's National Bioethics Advisory Commission (NBAC), the
first presidential bioethics panel to recommend federal funding for
human embryonic stem cell research (hESCR).
A research team said it has produced stratified retinal tissues from
human embryonic stem cells for the
first time in...
In 1998, a group led by Dr. James Thomson, who holds faculty appointments at the University of Wisconsin and the University of California, Santa Barbara (UCSB), isolated
embryonic stem cell from
humans for the
first time.
«The current extension of induced pluripotency to
human cells is a major development and although it is early days for this technique it may well prove to be every bit as signifcant as the
first derivation of
human embryonic stem cells nine years ago.
Treating Spinal Cord Injuries: 2009 also saw the
first FDA - approval of the use of
human embryonic stem cells in a clinical trial.