Sentences with phrase «first human infection»

Guinea worm, one of humanity's most painful and gruesome parasites, is on track to be eradicated — the first human infection to be wiped out since smallpox in 1980 (see «Parasite lost: Exterminating Africa's horror worms»).

In March 2013 the first human infections with the avian influenza A (H7N9) virus were reported in China, and since that time hundreds of cases have been documented.

Not exact matches

To determine whether a completely human milk based diet during the first 10 days of life reduces the combined incidence of serious infection, NEC, and mortality as compared to formula feeding and 2.

«Our research is the first to study Zika infection in a mouse model that transmits the virus in a way similar to humans,» explains Alysson R. Muotri, Ph.D., professor and director of the Stem Cell Program at UC San Diego and co-senior author of the study.

The discoveries reported in two independent studies in the American Journal of Human Genetics on January 7 add to evidence for an important role for interspecies relations in human evolution and specifically in the evolution of the innate immune system, which serves as the body's first line of defense against infecHuman Genetics on January 7 add to evidence for an important role for interspecies relations in human evolution and specifically in the evolution of the innate immune system, which serves as the body's first line of defense against infechuman evolution and specifically in the evolution of the innate immune system, which serves as the body's first line of defense against infection.

Fever is a first - line infection fighter in humans as well.

In human donor cells and mouse experimental models, the researchers demonstrated that TSLP specifically targeted neutrophils — white blood cells that constitute the first line of defense against bacterial infections.

The first report of infections of humans with the influenza A virus of the subtype H7N9 surfaced in March 2013.

Clinicians treating patients suffering from Middle East respiratory syndrome (MERS) currently have no drugs specifically targeted to the MERS coronavirus (MERS - CoV), a virus first detected in humans in 2012 that has since caused 614 laboratory - confirmed infections, including 181 that were fatal, according to the World Health Organization.

This is particularly true within the human body, where iron is concealed in cells and large iron - binding proteins as a first line of defense against infection.

These are some of the fastest migrating cells in the human body, and they are the first responders at damaged locations or areas of infection and begin the process of healing.

These images provide the first 3D ultrastructural details on HIV infection and virus production in a setting that closely resembles the gut of human patients.

This pushes back the first recorded case of AIDS in the US by about a decade: the only earlier known case of human HIV infection was in Zaire in 1959.

The findings make sense, he says, because the first human flu infections were seen in Mexico before the 2009 pandemic spread rapidly to the United States and then around the globe.

The first human trials will be done in the US in October with people at low risk of subsequent Zika or dengue infection, says Michael.

Using cells from mice and human livers, Toronto General Hospital Research Institute researchers demonstrated for the first time how under specific conditions, such as obesity, liver CD8 + T cells, white blood cells which play an important role in the control of viral infections, become highly activated and inflammatory, reprogramming themselves into disease - driving cells.

A holistic understanding of the role of Earth's microbial community and its genome — its microbiome — in the biosphere and in human health is key to meeting many of the challenges that face humanity in the twenty - first century, from energy to infection to agriculture.

«The first generation GAP strain had two genes removed from the malaria parasite, but this new «triple punch», developed in collaboration with scientists at the Walter and Eliza Hall Institute in Australia, removes three separate genes associated with the pathogenicity of the parasite, effectively abrogating its ability to establish an infection in humans.»

About OpenBiome OpenBiome is the first public stool bank, founded to expand safe access to fecal transplantation for patients with recurrent C. difficile infection and to catalyze research on the microbiome's role in human health.

7/16/2008 Improved Culture System for Hepatitis C Virus Infection A University of California, San Diego School of Medicine researcher has developed the first tissue culture of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible..Infection A University of California, San Diego School of Medicine researcher has developed the first tissue culture of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible..infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible... More...

April 10, 2018 - The human piece of a malaria infection puzzle has been revealed for the first time, solving a long - standing mystery.

The human piece of a malaria infection puzzle has been revealed for the first time, solving a long - standing mystery.

The trials would be for proof of concept, to show whether researchers can, for the first time in humans, stimulate the right B cells to start the process of making broadly neutralizing antibodies, long considered the «holy grail» of HIV vaccine research because they defend against infection by a broad spectrum of HIV strains.

• Patients must have adequate coagulation (international normalized ratio (INR) or prothrombin time (PT), partial thromboplastin time (PTT) ≤ 1.5 times ULN) • Adequate liver function (total bilirubin ≤ 1.5 times the ULN, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 2.5 times ULN Exclusion Criteria: • Presence of active / uncontrolled central nervous system involvement • History of clinically significant cardiac disease; uncontrolled hypertension • Left ventricular ejection fraction (LVEF) < 45 % • Allogeneic stem cell transplant within 100 days before first dose of study drug • Known history of human immunodeficiency virus (HIV) infection • Chronic or active hepatitis B or C, requiring antiviral therapy • Evidence of history of bleeding disorder, dialysis, or coexisting cancer that is distinct in primary site or histology from the cancer evaluated in this study • Serious, uncontrolled infection • Unresolved chronic toxicity > grade 1 from prior therapy • Use of strong CYP3A4 inhibitors or strong inducers within 7 days prior to the start of study treatment and for the duration of the study

He and his colleagues were the first to demonstrate that human antigen - specific T cell clones could be isolated and expanded in vitro and then re-infused into patients to prevent or treat viral infections and to mediate therapeutic responses in patients with cancer.

LA JOLLA — For the first time, scientists have turned human skin cells into transplantable white blood cells, soldiers of the immune system that fight infections and invaders.

In fact, some researchers now think the very first HIV infection in humans may have happened more than 100 years ago, in 1908 or earlier.

I practice primary care family medicine, and I also have special areas of interest in the immune system (linked to autoimmune diseases, skin conditions, chronic infections, and the human microbiome), and in helping first responders optimize their health to prevent conditions and challenges common to their jobs.

«In this case of first impression, the majority holds that a wife who sues her husband claiming that he negligently infected her with the human immunodeficiency virus (HIV) is not limited to a theory that he did so knowing he was HIV positive but that liability also extends «to those situations where the actor, under the totality of circumstances, has reason to know of the infection.»»