«Cellular system makes the battle against a rare disease personal: Scientists develop
the first human stem - cell based system to find drugs to fight mitochondrial disease.»
Not exact matches
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FIRST to those who have suffered the abuse that
stemmed from or was abetted by troublesome theology (whether it be formal volunteering, donating money or goods or even just validating that a victim is not crazy, not sinful and is a worth
human being and that their abuser was in the wrong.
As nearly all critics would agree, the attractiveness that Satan displays in the
first two books partly
stems from the impact of Romanticism; but as Fish already noted in his
first Milton book, the
human condition will always find Satan attractive, at least until he can capture the soul, for that susceptibility to the devil's charms is part of the legacy of original sin.
While scientists have previously had success in 3D printing a range of
human stem cell cultures developed from bone marrow or skin cells, a team from Scotland's Heriot - Watt University claims to be the
first to print the more delicate, yet more flexible,
human embryonic
stem cells (hESCs).
Since the
first human brain organoids were created from
stem cells in 2013, scientists have gotten them to form structures like those in the brains of fetuses, to sprout dozens of different kinds of brain cells, and to develop abnormalities like those causing neurological diseases such as Timothy syndrome.
First mouse cells were turned into «totipotent»
stem cells, and now early work suggests the same might have been achieved with
human cells
A recent federal court injunction based on a congressional budget amendment passed years before the
first human embryonic
stem cells were isolated has thrown many of the field's ongoing projects into limbo
Trials of cells made from
human embryonic
stem cells are also poised to begin in people with type 1 diabetes and heart failure, the
first time embryonic
stem cells have been used in the treatment of major lethal diseases.
In 2007, however, scientists at International
Stem Cell, a California - based biotech firm, reported the first successful creation of human stem cell lines from unfertilized e
Stem Cell, a California - based biotech firm, reported the
first successful creation of
human stem cell lines from unfertilized e
stem cell lines from unfertilized eggs.
«Our research is the
first to study Zika infection in a mouse model that transmits the virus in a way similar to
humans,» explains Alysson R. Muotri, Ph.D., professor and director of the
Stem Cell Program at UC San Diego and co-senior author of the study.
Geron was bigger and better funded than ACT, and it was the
first company to be approved by the US Food and Drug Administration (FDA) to test a therapy in
humans based on embryonic
stem (ES) cells.
«We've figured out for the
first time how to produce these cells from
human embryonic
stem cells literally by the billions and billions,» Lanza says.
Dr. Zubair, medical and scientific director of the Cell Therapy Laboratory at Mayo Clinic in Florida, says the experiment will be the
first one Mayo Clinic has conducted in space and the
first to use these
human stem cells, which are found in bone marrow.
Fraudulent cloned cells were likely the
first example of a
human egg turned directly into
stem cells
In a series of experiments, the researchers
first identified a set of 19 transcription factors that were expressed at significantly greater levels in cultured
human glioblastoma
stem cells capable of tumor propagation than in differentiated tumor cells.
Although British researchers had discovered embryonic
stem cells in laboratory animals in 1981, it wasn't until 1998 that a Wisconsin team announced it had isolated
stem cells from
human embryos for the
first time.
Eighteen adults with severe eye disease who were among the
first people to receive transplants created from
human embryonic
stem cells (hESCs) continue to have no apparent complications with the introduced cells after an average of nearly 2 years, according to the latest status report on their health.
Wells's team
first turned
human skin cells into pluripotent
stem cells, which can grow into any type of tissue.
Then, a team led by Robert Lanza, the chief scientific officer of Advanced Cell Technology Inc. in Marlborough, Massachusetts, and his colleagues published the
first results ever of a clinical trial using
human embryonic
stem cells.
First produced only in the past decade,
human induced pluripotent
stem cells (iPSCs) are capable of developing into many or even all
human cell types.
In the past year, the South Korean Food and Drug Administration (FDA) has approved the world's
first three
stem - cell treatments — Hearticellgram - AMI, Cupistem and Cartistem — which followed on the heels of clinical tests for
human embryonic
stem - cell therapies approved in 2010, according to the health ministry.
A person with spinal injuries today went down in history as the
first to receive a treatment derived from
human embryonic
stem cells (hESCs).
In May 2013, Mitalipov was the
first scientist in the world to demonstrate the successful use of somatic cell nuclear transfer, or SCNT, to produce
human embryonic
stem cells from an individual's skin cell.
«It's taken years of trial and error, making educated guesses and taking baby steps to finally produce functioning
human muscle from pluripotent
stem cells,» said Lingjun Rao, a postdoctoral researcher in Bursac's laboratory and
first author of the study.
Tufts University biomedical engineers recently published the
first report of a promising new way to induce
human mesenchymal
stem cells (or hMSCs, which are derived from bone marrow) to differentiate into neuron - like cells: treating them with exosomes.
Now comes a
first rate example of how CRISPR is changing the pace of biomedical research by linking up with another cutting edge technology —
human pluripotent
stem cells (hPSCs).
The results obtained by Afsaneh Gaillard's team and that Pierre Vanderhaeghen at the Institute of Interdisciplinary Research in
Human and Molecular Biology show, for the
first time, using mice, that pluripotent
stem cells differentiated into cortical neurons make it possible to reestablish damaged adult cortical circuits, both neuroanatomically and functionally.
We take a
human embryonic
stem cell, and we inject it into a monkey blastocyst [the
first 130 or so cells in a newly formed embryo].
Starting in the mid-2000s, Yoshiki Sasai's team at the RIKEN Center for Developmental Biology in Kobe, Japan, demonstrated how to grow brainlike structures using embryonic
stem cells,
first from mice and then
humans.
Ko
first cloned the
human GT198 gene while a postdoctoral fellow at Harvard Medical School, and subsequent studies by her and others have shown it has multiple roles that also include regulating
stem cells, cell suicide and turning other genes off and on.
Kotton built a reporter gene that glowed green when the
stem cells
first expressed Nkx2 - 1, and Hawkins engineered the same gene into
human cells.
But after learning that work by South Korean scientist Woo Suk Hwang had been faked, the journal Science retracted Hwang's landmark papers from 2004 and 2005, which reported the
first human embryonic
stem cells from cloned embryos.
In May 2006, Eggan's lab received approval from Harvard to seek healthy
human eggs from female donors, a
first step toward using research cloning to create new
stem cell lines.
The work was led by Dan S. Kaufman, a hematologist, and James A. Thomson, the
first scientist to grow
human embryonic
stem cells in culture.
In June Italian scientists announced the
first human embryonic
stem cells derived from parthenotes — embryo - like structures formed when an egg starts to divide on its own, with no sperm involved.
THE world's
first cloned
human embryonic
stem cells (hESCs) are here, but they can't yet be used to grow tissues for transplant because they have an extra set of chromosomes.
Usually
human stem cells that we grow in the lab have already begun to differentiate, but last year my team provided the
first evidence that we can maintain them in a more naive state.
«The LSC17 score is the most powerful predictive and prognostic biomarker currently available for AML, and is the
first stem cell - based biomarker developed in this way for any
human cancer,» says Dr. Wang.
In the decade since the
first human embryonic
stem cells were isolated, the science surrounding
stem cells has grown dramatically.
In the current study, published in the Proceedings of the National Academy of Sciences, the researchers produced V2a interneurons from
human stem cells for the
first time.
Amid all this, are you still trying to achieve your
first dream, harvesting embryonic
stem cells from
human clones?
This will mark the start of the
first clinical trial in China using
human embryonic
stem (ES) cells, and the
first one worldwide aimed at treating Parkinson's disease using ES cells from fertilized embryos.
In February 2004 Hwang and his research group reported the
first embryonic
stem cell line derived from a cloned
human embryo.
Using a 3D,
stem cell - based model of a
first - trimester
human brain, the team discovered that Zika activates TLR3, a molecule
human cells normally use to defend against invading viruses.
A U.S. - based company has received permission to start Europe's
first clinical trial involving
human embryonic
stem (hES) cells.
Another team, from Stanford University, converted
human skin cells directly into neurons without
first stopping at the
stem cell stage, potentially making the process more efficient.
UC announced yesterday that it is the
first research institution to seek to «intervene,» or become a party in the case, in which the government is appealing a lower court's ruling that National Institutes of Health (NIH) funding to study
human embryonic
stem cells (hESCs) violates federal law.
They found that the model's
stem cells differentiate (specialize) into the various cells of the brain in the same way that they do in the
first trimester of
human development.
He used adult cells —
first in mice, although the technique is now feasible in
human cells — to make
stem cells that can form a wide range of other cells, essentially turning their cellular clocks back to infancy so they could mature into different adults.
The result follows on the heels of an announcement last month by another California
stem cell company, International Stem Cell Corporation (ISC) in Oceanside, that it had successfully achieved human parthenogenesis for the first t
stem cell company, International
Stem Cell Corporation (ISC) in Oceanside, that it had successfully achieved human parthenogenesis for the first t
Stem Cell Corporation (ISC) in Oceanside, that it had successfully achieved
human parthenogenesis for the
first time.