Sentences with phrase «first known risk factor»

BRCA1 and 2, genes whose proteins are supposed to work as tumor suppressors and also repair DNA damage, were the first known risk factor genes for familial breast cancer as well as ovarian and other cancers.

Not exact matches

She knew this about me, about my admission to medical school and dropping out, and on the basis of the internal factors which drove me, in the past, to get into medical school, so calculated that I was not much of a risk at all even though I was broke and continued to be so for the first three years of our marriage.

Since APOE4 was first linked to Alzheimer's disease almost 30 years ago, it remains the strongest known genetic risk factor for this disease.

This study is the first to determine whether solitary drinking during teenage years impacted the development of alcohol use disorders as young adults, after controlling for other known risk factors.

Professor Jeremy Pearson, Associate Medical Director at the BHF, which part - funded the study, said: «By using the power of very large scale genetic studies, this research is the first to show that the known association between increased height and a lower risk of coronary heart disease is at least in part due to genetics, rather than purely down to nutrition or lifestyle factors.

This is the first study to evaluate risk factors of food - induced anaphylaxis to a known food allergen in children.

There are several risk factors — having first - degree relatives with pancreatic cancer, chronic pancreatitis, obesity, diabetes, tobacco smoking and alcohol consumption, for example — but it's not known how these risk factors trigger the conversion of a PanIN1 lesion to cancer.

First, it's important to know that family history is one of the greatest risk factors for certain cancers.

* Recent analyses indicate that environmental factors associated with vocabulary development and emergent literacy skills are already present among children as early as 15 months of age.2 By first grade, unfortunately, the repercussions become all too clear: children from high - income families are likely to know about twice as many words as children from low - income families, putting these children at a significantly higher risk for school failure.3

To develop a suitable plan for your retirement investments, we first get to know you and your risk tolerance calculating your net worth, identifying your financial objectives, cash flow needs, investment experiences, financial circumstances, and current investments (stocks, bonds, mutual funds, real estate, etc.), among other factors.

Trajectories of Offending Behavior Having reviewed trends in female offending patterns, subsequent interactions with the justice system, and the ultimate outcomes of such offending, I now turn my attention to what is known about how girls get into trouble in the first place, including typical trajectories of offending (in this section) as well as risk and protective factors (in the section that follows).

To our knowledge, this is the first study to uncover the association between maternal — infant relationship qualities (sensitivity, control, unresponsiveness) and childhood AD after accounting for risk (maternal depression, anxiety and stress) and protective (social support) factors and well - known covariates.