Sentences with phrase «first molecular studies»
In one of the first molecular studies of the human antibody response to yellow fever, Howard Hughes Medical Institute (HHMI) researchers and their colleagues have found the crucial bit of virus that...
http://www.hhmi.org/ Not exact matches
Straticyte is the first and only molecular diagnostic test for oral precancerous lesions that provides an objective and accurate prediction score as evidenced by retrospective clinical studies.
And he ran down SoHe who was only 22 and a Toronto university studying molecular biology and he aimed the steering wheel at Betty and accelerated — Betty whose mother had long ago named her Mary Elizabeth — and who was revelling in one of the first warm April days in her 95th — and last — spring on this spinning orb.
«This study is the first to demonstrate evidence for both keratin and melanosomes, using structural, chemical and molecular methods,» says Pan.
I first became aware of bioinformatics while in graduate school at the University of Colorado, Boulder, studying molecular, cellular, and developmental biology.
«This new study uncovers for the first time the dynamic of stem cells during wound healing and identifies new molecular players associated with skin regeneration.
Research for the study was conducted by first co-authors Dr. Ranit Kedmi and Nuphar Veiga and colleagues at Prof. Peer's TAU Laboratory, in collaboration with Prof. Itai Benhar of TAU's School of Molecular Cell Biology and Biotechnology, Dr. Michael Harlev of TAU's Veterinary Service Center, Dr. Mark Belkhe of Integrated DNA Technologies (IDT) and Prof. Judy Lieberman of Boston Chidren's Hospital and Harvard Medical School.
This is important because current DNA studies, known as «molecular clocks», which are used to estimate how long ago a group animals originated, suggests the first animals appeared before these burrows.
«Sea turtle crisis: Moisture, not just heat impacts sex of sea turtle hatchlings: Sex - ratio study first to use molecular marker to explain why and how moisture affects the nest.»
The study represents the first glimpse into how domestic cats perceive bitterness in food at a molecular level, and could explain why cats are sometimes such picky eaters.
As a researcher, Hockfield was among the first scientists to apply molecular biology to neuroscience, using monoclonal antibodies to study the brain.
The latest findings reinforce a 2016 Storz - led study published in the journal Science, which was the first to establish that vertebrate species can follow different molecular - level paths to reach the same adaptation.
The study is the first to identify the molecular consequences of RB loss and illustrate the clinical relevance of RB - loss - induced transcriptional rewiring.
The study, published in Molecular Cell, describes the new antibiotic and, for the first time, how it works.
«Proper blood cell production is dependent on functioning hematopoietic stem and progenitor cells that are destroyed during conditioning procedures for transplantation or following bone marrow injury,» said the study's first author Kevin A. Goncalves, who performed this research as part of his PhD studies in cellular and molecular physiology at the Sackler School.
The first study used fruit flies as an in vivo test system to reveal new evidence about the function of a key influenza protein called NS1, which has evolved to target molecular pathways in the host.
A team led by Latha Venkataraman, professor of applied physics and chemistry at Columbia Engineering and Xavier Roy, assistant professor of chemistry (Arts & Sciences), published a study today in Nature Nanotechnology that is the first to reproducibly demonstrate current blockade — the ability to switch a device from the insulating to the conducting state where charge is added and removed one electron at a time — using atomically precise molecular clusters at room temperature.
The study, which appears in the current issue of the journal Genome Biology, is the first to reveal on a molecular level how loneliness puts people at risk for disease, says Cole.
The team of researchers was the first in the world to use modern genetic, molecular and biochemical methods to study tooth enamel defects in detail.
This is the first study to describe the roles of the molecular chaperone gp96 in maintaining gut homeostasis.
Their study is the first of its kind in the ear field and helps resolved the molecular aspects of the cellular complexity of the inner ear.
«This study gives us the molecular basis for seedlessness, which is the first time this has been done for a fruit plant,» Gasser says.
This study was the first major Alzheimer's clinical trial to require molecular evidence of amyloid deposition in the brain for enrollment.
«Our method permits the analysis of minute biopsies and even tissue micro-arrays, making it particularly interesting for molecular research and diagnostics,» explains doctoral candidate Achim Buck, together with Alice Ly, the first author of the study.
However, the work published on Molecular Psychiatry and first signed by the expert Claudio Toma provides an innovative view on the study of ASDs genetics: «It is the first time that mutations transmitted to children by any of the progenitors are studied in a genomic perspective.
The basic lines of his current work are three: in the first place, the study of evolutionary relations within aphids as well as the evolution of their life cycles; in the second place, the molecular bases that control the seasonal and circadian rhythms in aphids (and in insects in general) and their relation to vital cycles; and finally, myrmecophily in aphids, recently included.
The study is «a real feat,» says Sven Andersen, a molecular biologist at the University of Copenhagen, Denmark, and part of the team that first found the resilin gene.
«While more work is required to elucidate the cellular and molecular mechanisms through which B cells exert their beneficial function in wound healing, we are in the process of obtaining the required regulatory approvals to conduct a first clinical study in patients with diabetic foot ulcers.
For the first time, scientists have used Positron Emission Tomography (PET) imaging to study brain inflammation following Zika virus infection in mice, according to a study recently published online in the journal Molecular Imaging and Biology.
«This is the first study to offer an unbiased profile of novel imprinted genes in a mammal other than mice,» said lead author Xu Wang, a postdoctoral associate in the laboratory of Andrew Clark, professor of molecular biology and genetics and the study's senior author.
«Ours is the first study to define the dormant niche on a cellular and molecular basis, and it is interesting that the culprit is the tissue we so often assume is a passive bystander, the microvascular endothelium,» Ghajar says.
Moffitt researchers performed molecular studies to show for the first time that SETDB1 is constitutively modified by a single ubiquitin molecule.
«Dietary therapies for Crohn's disease should be examined more systematically, and this study provides a good first step,» said Dennis Ko, an assistant professor of molecular genetics and microbiology in the Duke School of Medicine.
Understanding the molecular mechanisms underlying Aurora kinase - overexpressing tumours will help in the design of targeted and personalised cancer therapy,» said Dr Linda Chuang, Senior Research Scientist at CSI Singapore, who is the first author of the study.
«This is the first time anybody has used optogenetic techniques to stimulate the immune system, much less to fight cancer cells,» said study author Gang Han, PhD, assistant professor of biochemistry & molecular pharmacology at UMass Medical School.
«Although this was a small, preliminary study, it suggests that marijuana may affect individuals at high risk for psychosis differently than other marijuana users, by briefly inducing psychotic - like experiences and impairing their cognition,» said Nehal Vadhan, PhD, a psychologist and associate professor in Psychiatry and Molecular Medicine at Hofstra Northwell School of Medicine and first author of the paper.
A team of scientists from the University of North Carolina School of Medicine, North Carolina State University's College of Veterinary Medicine and Duke University have conducted one of the first studies to directly compare canine and human B - cell lymphoma by examining molecular similarities and differences between the two species.
«This is one of the first comprehensive studies to look at rates of molecular evolution in dolphins.»
These studies, performed at Ohio University, are the first to identify the molecular mechanism of vitamin D3 - triggered restoration of the function of damaged endothelium in the cardiovasculature.
«Recognizing MMP - 20's function in biomineralization is one of the first steps to learning how dental enamel forms in nature,» said Qichao Ruan, lead author of the hydrogel study and a postdoctoral research associate in the Center for Craniofacial Molecular Biology at USC.
«This study expands our molecular understanding of C2c2 to guide RNA processing and provides the first application of this novel RNase,» said Doudna, who is also a Howard Hughes Medical Institute investigator.
Senior author and IMBA group leader Kikuë Tachibana - Konwalski is fascinated by the secrets of the mammalian oocyte - to - zygote transition and has been studying the miracle of life, and in particular the very first molecular steps, for many years.
The strong link between the first - term exposure and birth weights makes sense, said Vasantha Padmanabhan, senior author of the study and professor of pediatrics, obstetrics and gynecology, molecular and integrative physiology and environmental health sciences at the University of Michigan.
A large new study from the Psychiatric Genomics Consortium provides the first molecular genetic evidence that genetic influences play a role in the risk of getting Posttraumatic Stress Disorder (PTSD) after trauma.
«Drug treatments for schizophrenia have barely changed over the past few decades, as they still target dopamine receptors,» says study co-author Dr Andrew McQuillin, head of the UCL Molecular Psychiatry team that first discovered GRM3.
«Our finding of a link between bipolar disorder and the striatum at the molecular level complements studies that implicate the same brain region in bipolar disorder at the anatomical level, including functional imaging studies that show altered activity in the striatum of bipolar subjects during tasks that involve balancing reward and risk,» said TRSI Research Associate Rodrigo Pacifico, who was first author of the new study.
An important step towards this goal is the first highly contiguous genome assembly of Schmidtea mediterranea that researchers at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI - CBG) in Dresden in cooperation with the Heidelberg Institute for Theoretical Studies (HITS) report in the current issue of Nature.
«This is the first systematic comparison of the mouse and human at the genomic level,» said Bing Ren, Ph.D., co-senior author on the Consortium's main Nature study and professor of cellular and molecular medicine at the University of California, San Diego.
This is the first study to suggest that it might be possible to personalize recommended diets for breast cancer survivors based on the molecular characteristics of their primary tumor.
More than 20 years ago, in a study that triggered both scientific and cultural controversy, the molecular biologist offered the first direct evidence of a «gay gene,» by identifying a stretch on the X chromosome likely associated with homosexuality.