TUESDAY, April 17, 2018 (HealthDay News)-- The millions of Americans who suffer from migraine may have a new source of hope —
the first of a new class of drugs aimed at warding off the headaches.
Not exact matches
OCA is the
first in a
new class of drugs, farnesoid X receptor (FXR) agonists, and the response
of the patients to OCA shows that abnormalities in the system it targets may be critical for this condition.
In August, for the
first time in more than a decade, the FDA approved a
new class of antiretroviral
drugs called entry inhibitors.
He notes, however, that in the wake
of the criminalization
of first - generation cathinone derivatives,
new members
of this
drug class are being invented that will also require study.
Sangamo biochemist Philip Gregory notes that this Phase 1 clinical trial is the
first human test
of an entirely
new class of drug that could turn any gene on or off, depending on the disease.
«We
first tried a histone methylation inhibitor — a promising
new class of cancer
drugs — but that did not restore p16 or had any effect on tumor growth.
«This study is the
first step in a potential
drug development for a
new class of drugs for osteoarthritis, although there are a number
of hurdles we have to go through — necessarily so — before it gets nearer patients.
A «game changing»
new antibiotic which is capable
of killing superbugs has been successfully synthesised and used to treat an infection for the
first time — and could lead to the
first new class of antibiotic
drug in 30 years.
The
first three - dimensional image capturing a critical malaria «conductor» protein could lead to the development
of a
new class of antimalarial
drugs.
The good news is that since 2005, the WHO has been coordinating a worldwide effort to find
new TB
drugs, and as
of December 2013 two
new classes of drug had been approved, the
first for 40 years.
Early results from a phase I,
first in - human study indicate that a potential
new class of drugs, RNA interference (RNAi)
drugs, can be safely administered in humans, according to a researcher who presented data on the safety and preliminary efficacy
of TKM - 080301 at the AACR Annual Meeting 2013, held in Washington, D.C., April 6 - 10.
Tu also received numerous awards nationally which include «Award for Progress in Anti-malarial Research Achieved by Project 523 Scientific Team» honored by China National Congress
of Science and Technology (1978); «National Scientific Discovery Award» for Anti-malaria
Drug - Qinghaosu by the China Ministry
of Science and Technology (1979); «Invention Award» (as the
first inventor) by China National Congress for Awards in Science and Technology (1982); «Award of Young and Middle - aged Experts with Outstanding Contribution» by the Chinese Government (1984); «The Top Honorary Award» by China Academy of Traditional Chinese Medicine (1992); «The Top Ten National Achievements for Progress in Science and Technology» by China National Committee of Science and Technology (1992); «First - Class Award of National Achievements in Science and Technology» by China National Award Committee for Advances in Science and Technology (1992); «National Model» by China State Council (1995); «Award for Outstanding Achievement in Traditional Chinese Medicine» by Guangzhou Zhongjing Award Foundation for Traditional Chinese Medicine (1995); «Outstanding Scientific Achievement Award» by Qiu Shi Science and Technologies Foundation of Hong Kong (1996); «Top Ten Health Achievements in New China» by China Ministry of Health (1997); «Female Inventor of the New Century» by China National Bureau of Intellectual Property (2002); «Golden Medal of the 14th National Invention Exhibition» by China National Bureau of Intellectual Property (2003); «Award for Development of Chinese Materia Medica» by Cyrus Chung Ying Tang Foundation, (2
first inventor) by China National Congress for Awards in Science and Technology (1982); «Award
of Young and Middle - aged Experts with Outstanding Contribution» by the Chinese Government (1984); «The Top Honorary Award» by China Academy
of Traditional Chinese Medicine (1992); «The Top Ten National Achievements for Progress in Science and Technology» by China National Committee
of Science and Technology (1992); «
First - Class Award of National Achievements in Science and Technology» by China National Award Committee for Advances in Science and Technology (1992); «National Model» by China State Council (1995); «Award for Outstanding Achievement in Traditional Chinese Medicine» by Guangzhou Zhongjing Award Foundation for Traditional Chinese Medicine (1995); «Outstanding Scientific Achievement Award» by Qiu Shi Science and Technologies Foundation of Hong Kong (1996); «Top Ten Health Achievements in New China» by China Ministry of Health (1997); «Female Inventor of the New Century» by China National Bureau of Intellectual Property (2002); «Golden Medal of the 14th National Invention Exhibition» by China National Bureau of Intellectual Property (2003); «Award for Development of Chinese Materia Medica» by Cyrus Chung Ying Tang Foundation, (2
First -
Class Award
of National Achievements in Science and Technology» by China National Award Committee for Advances in Science and Technology (1992); «National Model» by China State Council (1995); «Award for Outstanding Achievement in Traditional Chinese Medicine» by Guangzhou Zhongjing Award Foundation for Traditional Chinese Medicine (1995); «Outstanding Scientific Achievement Award» by Qiu Shi Science and Technologies Foundation
of Hong Kong (1996); «Top Ten Health Achievements in
New China» by China Ministry
of Health (1997); «Female Inventor
of the
New Century» by China National Bureau
of Intellectual Property (2002); «Golden Medal
of the 14th National Invention Exhibition» by China National Bureau
of Intellectual Property (2003); «Award for Development
of Chinese Materia Medica» by Cyrus Chung Ying Tang Foundation, (2009).
Leelamine could be the
first of a
new unique
class of drugs that will simultaneously target several protein pathways.
Leelamine is the
first of a
new class of potentially viable
drugs for the treatment
of melanoma.
Dr. Vilcek's contributions to the understanding
of proteins that control the body's defenses were instrumental in the development
of the anti-inflammatory
drug Remicade ®, the
first member
of a
new class of therapeutics called TNF blockers that are now widely used for the treatment
of Crohn's disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriasis, and other chronic inflammatory disorders.
This candidate
new drug, a
first - in - its -
class, shows activity against a broad range
of tumor types in mice and appears safe at this stage.»
Reykjavik, ICELAND, January 13, 2005 — deCODE genetics (Nasdaq: DCGN) has submitted an investigational
new drug application (IND) to the U.S. Food and Drug Administration (FDA) for DG041, a novel, first - in - class, orally - administered small molecule for the treatment o
drug application (IND) to the U.S. Food and
Drug Administration (FDA) for DG041, a novel, first - in - class, orally - administered small molecule for the treatment o
Drug Administration (FDA) for DG041, a novel,
first - in -
class, orally - administered small molecule for the treatment
of...
Invokana (canagliflozin) was the
first drug of a
new class of diabetes
drugs known as sodium - glucose cotransporter - 2 (SGLT2) inhibitors.
More than one - third
of the novel
new drugs approved in 2014 (17
of 41 or about 41 %) were identified as
First - in -
Class and about 41 %
of the novel
new drugs approved in 2014 (17
of 41) were approved to treat rare or «orphan» diseases.