Sentences with phrase «first randomised»

In 2008, the first randomised controlled trial was undertaken to look at the specific efficacy of the ketogenic diet in children compared to a control (9).
This is shown by researchers at Uppsala University in the first randomised study in the world comparing two ways of identifying cervical cancer, published today in the British Journal of Cancer.
The Finnish Diabetes Prevention Study was the first randomised, controlled lifestyle intervention study to show that in persons with impaired glucose tolerance, type 2 diabetes can be prevented by lifestyle changes.
Professor Taborsky said: «This is the first randomised trial comparing the effects of red and white wine on markers of atherosclerosis in people at mild to moderate risk of CVD.
The Maternal Vitamin D Osteoporosis Study (MAVIDOS) is the first randomised, placebo - controlled trial designed to measure the impact of pregnancy vitamin D supplementation on the bone health of babies using bone density scanning.
This is the first randomised clinical trial using as a research tool a high - fidelity simulation mannequin with a physiological response as a human being, a medical vehicle and volunteering healthcare practitioners from the Alicante Health Emergency Service (SES).
Taking vitamin D supplements during pregnancy, as recommended for all women under UK guidelines, has no significant effect on the bone density of babies, according to the first randomised controlled trial of its kind, published in The Lancet Diabetes & Endocrinology journal.
«This is the first randomised trial to show that fecal transplantation may be of benefit to patients with hepatic encephalopathy.
Commenting on the trial, Dr Alice Shaw, director of thoracic oncology at the Massachusetts General Hospital Cancer Centre in Boston, US, said: «This is the first randomised study to examine how a second generation ALK inhibitor compares to standard second line chemotherapy in ALK positive patients who failed the standard first line therapy, which currently is crizotinib.»
It is the first randomised study in the world to be published and it was based on screened population and carried out in a digital treatment environment as a secondary prevention parent training.
This is the first randomised trial comparing options for home management of uncomplicated severe acute malnutrition (SAM).
The DAME study was the first randomised controlled trial to test the practice of antenatal hand expression of colostrum.

Not exact matches

The 12 week clinical study from the US of 303 participants is the first prospective, randomised clinical trial to directly compare the effects of water and diet beverages on weight loss within a behavioural weight loss program.
In reality, EFSA had told the Commission in a letter: «The evidence, however, does not establish that starting DHA supplementation at 4 - 6 months in infants who had received a control (DHA - free) formula in the first months of life would have an effect on the visual development of those children...... There are no data from specific randomised control trials supporting a benefit of DHA supplementation starting at 6 months of life in infants fed a DHA - free formula in the first 6 months of life......» (3)
A formative study using participatory action research design will first be conducted, followed by a cluster - randomised trial utilising both qualitative and quantitative data collection methods.
For the first time, researchers have shown in a randomised trial that looking at pictures of skinny models is enough to change a person's body ideals
Now for the first time there has been long - term follow - up of a randomised trial comparing people who reduced their use of antipsychotics with those who continued their treatment.
First, it provides a strong argument against the opinion that subgroup analyses of randomised trials should be strongly discouraged because they can lead to false positive findings due to the multiple comparison problem.
Freeman's team at UCL is doing a randomised trial comparing cannabidiol with a placebo in 48 people, expanding to 168 people if the first results are positive.
«How lifestyle intervention for weight loss affects birth rates in women with a high BMI: Results from the first major randomised trial.»
Following first - line treatment, patients experiencing disease progression were randomised 1:1 to receive second - line treatment of FOLFOX plus cetuximab (Arm A; n = 74) or sole FOLFOX (Arm B; n = 79).
For the first time, researchers have shown in a randomised trial that looking at photos of thin women is enough to shape a person's beauty ideals.
However, the first Mayo trial, designed to be double - blind, randomised, placebo - controlled research and purporting to have duplicated the conditions in Cameron's clinical trial, disproved the Cameron - Pauling thesis.
Ciara Reilly, Chief Executive of Every Day Harmony, the music therapy charity that was a partner in the research, said: «Music therapy has often been used with children and young people with particular mental health needs, but this is the first time its effectiveness has been shown by a definitive randomised controlled trail in a clinical setting.
The IVV study is the first long - term, prospective randomised trial comparing the effect of red and white wine on markers of atherosclerosis.
The study was prompted by conjecture about the causative relationship between periodontal (gum) disease and atherosclerotic vascular disease and is among the first using a randomised trial to investigate a periodontal intervention on atherosclerotic disease.
Bornhäuser M, Kienast J, Trenschel R, et al Reduced - intensity conditioning versus standard conditioning before allogeneic haemopoietic cell transplantation in patients with acute myeloid leukaemia in first complete remission: a prospective, open - label randomised phase 3 trial.
Palma P, Romiti ML, Montesano C, Santilli V, Mora N, Aquilani A, Dispinseri S, Tchidjou HK, Montano M, Eriksson LE, Baldassari S, Bernardi S, Scarlatti G, Wahren B, Rossi P. Therapeutic DNA vaccination of vertically HIV - infected children: report of the first pediatric randomised trial (PEDVAC).
One part of the study is to include the first large randomised control trial of mindfulness training involving nearly 6,000 students and running for five years.
What mixes up multiplayer are the randomised Vanguard gadget deployments which give whoever gets to them first some handy perks such as the previously mentioned Porcupine missiles or a UAV drone type device which allows you to blast opponents from orbit.
There are varying rules and stipulations throughout the championships; for instance Classic Championship Season contains 12 rounds worth of 5 laps, 25 %, 50 % or full distance races in which your 19 opponents can choose the same car as much as they want with points scoring reverting back to the former system of 10 points for a win and only the top six cars scoring points, while Sprint Championship contains six 5 lap races in which a full grid of modern cars have their grid order randomised for the first race with championship order being reversed to decide grid positions; therefore providing a set of unique championships that feel fresh and are thoroughly entertaining to participate in.
Ten randomised button prompts appear on the screen, the first to complete the string draws iron, the second eats lead!
It's a fascinating illustration of how to evolve a gameplay concept, and jettisons the linear structure of the first game in favour of a more open, randomised set - up, with each gameplay session differing greatly from the last.
Three - year follow - up of a randomised controlled trial to reduce excessive weight gain in the first two years of life: protocol for the POI follow - up study.
We report the results of the first Australian randomised trial of a sustained nurse home visiting intervention commencing antenatally and continuing to child - age 2 years for families living in a multicultural, socioeconomically disadvantaged urban community.
First multisite, multijurisdictional randomised controlled trial to test the effectiveness of sustained nurse home visiting in Australia.
2 randomised controlled trials evaluated home visitation by nurses for first time mothers of low socioeconomic status, single parents, or teenaged parents.
Queensland Aboriginal and Islander Health Council (QAIHC) data show good performance in risk factor monitoring and the management of hypertension and chronic disease.15 Box 2 shows improving performance in completion of health assessments — a first step in prevention activity — over the past 4 years.22 The Torpedo study, a randomised controlled trial of the use of an electronic decision - support system measuring absolute cardiovascular risk, shows ACCHSs outperforming general practices in managing risk.21 Data collected in late 2011 show that the ACCHSs sites had significantly more patients at high risk being prescribed best - practice medications than the general practice sites at baseline, and this gap was sustained through the intervention period (Box 3).23
The first is that nihilistic prognoses for borderline personality disorder are not evidence based, 2 psychoanalytic day hospital treatment and cognitive behavioural treatment3 have support from randomised controlled trials, and therapeutic communities have systematic review support.4 Nihilism may have arisen because treatment needs commitment, a clear model, time to influence behaviours, and a longer time to affect depression.
Two brief group - based parenting programmes have been subject to randomised controlled trials (RCTs); the first a cluster trial in Australia with parents of 8 - month - olds41 and the second an individually randomised trial in Germany with preschoolers.42 In these trials, although there has been some indication of changes in parental attitudes, no changes in parenting or child outcomes have been observed.
The first phase was a cluster randomised intervention trial in which general practices were randomly allocated to either an intervention group, in which nurse - led collaborative care was undertaken, or to a wait - list control group in which usual care led by the general practitioner (GP) was continued.
The effect of weekly short message service communication on patient retention in care in the first year after HIV diagnosis: study protocol for a randomised controlled trial (WelTel Retain)
The randomised controlled trial of Group Triple P, the first RCT of a western - developed parenting program in mainland China, found that Group Triple P significantly improved dysfunctional parenting and parental adjustment, increased parents» confidence and reduced child adjustment problems.
The randomised controlled trial of Group Triple P, the first RCT of a western - developed parenting program in mainland China, -LSB-...]
Effectiveness of a nurse - led intensive home - visitation programme for first - time teenage mothers (building blocks): A pragmatic randomised controlled trial.
Developing an Australian - first recovery model for parents in Victorian mental health and family services: a study protocol for a randomised controlled trial.
Detailed description of the trial's methods have been previously published.11 The cluster randomised trial was conducted in six socio - economically diverse18 local government areas (LGAs) in Victoria, Australia.11 Free universal health visits are scheduled from birth to 42 months of age, and over 90 % of parents attend visits during the first 6 months of life.19 Maternal and child health (MCH) nurses consecutively invited mothers of 6 - to 7 - month - old infants attending across August — September in 2004 to take part in the Toddlers Without Tears trial.
However, the potential of universal prevention in early childhood to improve mental health remains largely unexplored.2 5 7 We previously published short - term outcomes at toddler age11 of the first cluster randomised trial of a truly universal early parenting programme, Toddlers Without Tears, designed to be offered to all parents in the community and aiming to prevent externalising behaviours using anticipatory guidance before any developmental onset.
This is the first formal evaluation of adding a structured home intervention (HPS) to the IYP group - based programme and is a feasibility study to inform the design and implementation of a larger definitive randomised controlled trial.
Two studies have analysed cost effectiveness of CBT for severe health anxiety delivered in a conventional face - to - face format compared with treatment as usual using data from randomised controlled trials.8, 9 In the first study, it was found that CBT but not the control condition reduced consumption of primary and secondary healthcare contacts, but total costs were unchanged in both conditions.8 In the second study, a large - scale randomised trial, the health economic analyses showed that there were no significant differences between the two treatment conditions.9 In both of the above studies, CBT was superior in reducing health anxiety symptoms compared with treatment as usual, which means that as costs were similar across groups, CBT is likely to be the more cost - effective treatment option.
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