Sentences with phrase «first ribosome»

«You get this small product that is telling you the ribosome can not go through the 8 - oxo - G and then you get even smaller products that are telling you there are multiple ribosomes stuck behind the first ribosome.
When the first ribosome stops, the others pile up behind it.

Not exact matches

At the next stage, RNA molecules began to synthesize proteins, first by developing RNA adaptor molecules that can bind activated amino acids and then by arranging them according to an RNA template using other RNA molecules such as the RNA core of the ribosome.
Venkatraman Ramakrishnan, Thomas Steitz and Ada Yonath first determined how to image the ribosome, then revealed how it does its protein - making work
Elongation factor P binds to the ribosome so as to position the initiator transfer RNA for the first bond formation.
The latest such roster — 271 proteins identified in a compartment of the cell nucleus called the nucleolus — is a first step toward fully deciphering this organelle, a critical element in the construction of ribosomes, which build proteins.
The instructions for the synthesis of proteins are stored in the DNA in the cell nucleus, are first «transcribed» into mRNAs, and exported from the nucleus to the ribosomes in the cell cytoplasm.
Now, John Chaput and his colleagues at Arizona State University's Biodesign Institute have produced the first genome - wide investigation of cap - independent translation, identifying thousands of mRNA sequences that act as Translation Enhancing Elements (TEEs), which are RNA sequences upstream of the coding region that help recruit the ribosome to the translation start site.
To visualize translation, Dr. Singer and his colleagues took advantage of a key occurrence during the first round of translation: the ribosome to which mRNAs attach must displace so - called RNA - binding proteins from the mRNAs.
A ribosome looks at the first codon in a messenger RNA strand, finds the right amino acid for that codon, holds it, then looks at the next codon, finds its correct amino acid, stitches it to the first amino acid, then finds the third codon, and so on.
The power and glory of X-ray crystallography were that it was the first technique to show our eyes what the atomic world really looked like — initially for minerals and simple solids; then for small organic substances; eventually for giant molecules, macromolecular assemblies, and even organelles like the ribosome.
First, it stopped ribosomes from producing proteins, which slowed down the growth of the tumor.
First, her team studied the inhibition of ribosome activity in eubacteria, i.e., «good» bacteria.
We describe the first Niam embryonic stem cell interactome, which includes proteins with roles in DNA replication and repair, transcription, splicing and ribosome biogenesis.
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