OMP - 54F28 (FZD8 - Fc) and a sister compound also developed by OncoMed, vantictumab (OMP - 18R5), are two of
the first therapeutic agents targeting this key pathway to enter clinical testing.
It is our hope that the Phase 3 trial will result in
the first therapeutic agent for this condition.»
Not exact matches
When the institute tried injecting Ebola - infected animals —
first guinea pigs, then monkeys — with its
therapeutic agent encased in the lipid nanoparticles, the survival rate rose to 100 %, from around 20 % in previous trials.
«Exosomes were
first described in the mid-1980s, but we only now are beginning to appreciate their potential as
therapeutic agents.
Skin cells reprogrammed to act like embryonic stem cells — a breakthrough
first reported in human cells 2 weeks ago — are already showing promise as a
therapeutic agent.
The Vanderbilt findings provide «proof - of - concept that targeting an antitumor
agent to an intracellular protein may increase antitumor selectivity and improve the
therapeutic window for treating naturally occurring cancers,» said
first author Jashim Uddin, Ph.D., research associate professor of Biochemistry.
Our group has 3 major goals: Develop novel
therapeutic approaches based on centrosomal clustering To further develop our
first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant, asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to clinical trials To evaluate novel
agents in the preclinical setting and to initiate early phase clinical trials in hematologic malignancies with focus on multiple myeloma
The vaccine information is partially obtained from the AVMA's Council on Biologic and
Therapeutic Agents (AVMA Journal, Nov. 15, 2002) The
first question that you have to think about is whether you are trying to protect yourself against lawsuits, customer dissatisfaction and other problems or whether you are trying to protect the pets being boarded against acquiring diseases at your facility.