Sentences with phrase «flab dna»
At 12 months after antibiotic treatment, 8/10 antibiotic - treated mice had one or more flaB DNA - positive tissues, particularly tibiotarsus.
http://journals.plos.org/
The lower flaB DNA copy numbers in ticks that fed upon antibiotic - treated mice reflected either a lower capacity to replicate within ticks, reduced transstadial persistence of DNA, or acquisition of a lower number of spirochetes during feeding.
Among antibiotic - treated mice, 4/4 mice were test positive for flaB DNA qPCR at one or more tissue sites at 2 months, 2/4 mice were test positive for flaB DNA qPCR at only one tissue site at 4 months, and only 3/8 mice were test positive for flaB DNA qPCR at only one tissue site at 8 months.
In addition, flaB DNA - positive heart base and tibiotarsus from all 5 saline - treated infected mice were processed for comparison.
LDA analysis for RNA transcription of selected genes located throughout the B. burgdorferi cN40 genome in flaB DNA - positive heart base (HB) and tibiotarsal (Tt) tissue samples from infected mice at 12 months following treatment with saline or antibiotic.
Positive samples from antibiotic - treated mice were too sporadic for statistical comparison to samples from saline - treated mice, however, they indeed contained low flaB DNA copy numbers.
Quantitative real - time PCR (qPCR) was utilized to detect flaB DNA in tissue samples and ticks.
Despite the prevalence of flaB DNA in tibiotarsal tissue in both treatment groups, there was no evidence of joint inflammation (arthritis) or carditis in either group.