Sentences with word «flagellin»

FLS3 detects a part of the flagellum, a tail - like appendage that helps bacteria swim through their environment and consists mostly of flagellin proteins.
In particular, he has focused on targeting the gene coding for flagellin protein b, or flaB, which has proved to be quite distinct from one genospecies to the next.
Now new research from McGill University demonstrates yet another way that the humble cranberry may be a woman's best friend: «In lab studies, cranberry prevented the bacteria from producing a specific protein called flagellin, which is necessary for growing the tails that enable them to swim up the urinary tract and attach to cells,» explains lead study author Nathalie Tufenkji, PhD.
Alterations in bacterial species resulted in bacteria expressing more flagellin and lipopolysaccharide, which activate pro-inflammatory gene expression by the immune system.
Their findings confirm preclinical evidence that the agent, which is derived from salmonella flagellin, is worthy of further investigation as treatment for some of the most common and most resilient solid - tumor cancers.
The researchers determined which two pathogen - sensing molecules enable cells to recognize the injected flagellin.
Even though the virus doesn't have a flagellum, injecting the rodents with flagellin in advance protected them against the pathogen.
When the cells detect flagellin, they spur other cells to emit interleukin - 22 (IL - 22) and interleukin - 18 (IL - 18), molecular signals that help orchestrate a defensive response.
Rotavirus evolved to evade the body's antiviral defenses, but it can't counteract the response activated by flagellin or the combination of IL - 22 and IL - 18.
Indeed, injecting mice with IL - 22 and IL - 18 triggered the same antiviral effect as flagellin, the team found.
FLS3 is the second flagellin sensor discovered in tomatoes.
The first, called FLS2, is found in most land plants and detects invading bacteria by recognizing a separate region of flagellin called flg22.
The team identified a new receptor in tomato plants, called FLAGELLIN - SENSING 3 (FLS3), that triggers defenses against a bacterial attack.
Alterations in bacterial species resulted in bacteria expressing more flagellin and lipopolysaccharide, which can activate pro-inflammatory gene expression by the immune system.
The researchers were testing whether an injection of flagellin, a protein that's part of the tails (or flagella) some bacteria use to propel themselves, activates the body's antibacterial defenses.
When bacteria invade the plant, the FLS3 receptor binds to a region of the flagellin protein called flgII - 28 and triggers an immune response.
Since many plants have an FLS2 receptor, several bacterial species have acquired mutations in the flg22 portion of their flagellin, and these mutations alter the flagellin shape so that FLS2 can no longer recognize it.
Martin and his colleagues worked with postdoctoral researcher Christopher Clarke and Professor Boris Vinatzer at Virginia Tech, who previously identified flgII - 28 as a conserved segment of the flagellin protein that tomatoes can detect.
Examples include terminally mannosylated and polymannosylated compounds (which bind the mannose receptor) and various microbial components, such as bacterial lipopolysaccharide, hypomethylated DNA, flagellin and double - stranded RNA (all of which bind Toll - like receptors).
30.03.15 In the rest of the world, Salmonella Typhi has only one type of flagellin, the whip - like structure that helps it to move.
As a first line of defense against bacterial pathogens, plant cells recognize and respond to tiny bacterial molecules, such as pieces of flagellin that slough off the whip - like flagella that help the bacteria move.
«Individuals with wheat sensitivity had significantly increased serum levels of soluble CD14 and lipopolysaccharide (LPS)- binding protein, as well as antibody reactivity to bacterial LPS and flagellin.
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