Sentences with phrase «flavivirus disease»
Thus, in vitro enhancement assays lacked the ability to predict flavivirus disease severity in the rhesus macaque model.
https://www.sciencedaily.com/
«Prior dengue or yellow fever exposure does not worsen Zika infection in monkeys: Findings counter some concerns that prior flavivirus disease primes immune system to enhance Zika infection.»
Not exact matches
Flaviviruses are the cause of diseases spread by mosquitoes (e.g., dengue fever and West Nile fever) and by ticks (e.g., Powassan virus disease and tick - borne encephalitis).
WRAIR is moving forward with the purified inactivated virus (PIV) vaccine, called ZPIV, because it builds on «a type of vaccine that has been licensed before,» said Col. Stephen Thomas, an infectious disease Army physician and a vaccinologist specializing in flaviviruses, and the WRAIR Zika program lead.
«The Army was able to move so quickly in developing, manufacturing and testing a Zika vaccine because of its extensive experience with this vaccine platform and long standing investments in the understanding and mitigation of flaviviruses, like yellow fever, dating back to the founding of WRAIR,» said Dr. Kayvon Modjarrad, Zika program co-lead and associate director for Emerging Infectious Disease Threats at WRAIR's MHRP.
From preliminary epidemiology, pathogen isolation, and reproduction of the clinical disease by the isolated virus, BYDV, Koch's postulates were fulfilled, and a new flavivirus causing a serious duck disease was identified.
We performed a systematic investigation, from epidemiology, pathogen isolation, virus characterization, disease reproduction by infection with the isolated virus (fulfilling Koch's postulates), to virus genome sequencing and found that the duck egg drop disease was caused by a new flavivirus, BYD virus, that is closely related to Tembusu virus.
This is the first severe duck disease caused by a zoonotic flavivirus ever reported.
The high selectivity, and the potency with which some of these receptors promote flavivirus infection, suggest only a small number of receptors might be effectively targeted to treat these diseases.