Sentences with phrase «flavivirus infections»

«We want to understand which PS receptors contribute the most to flavivirus infections and how we might block them,» Choe said.

«These results support that the antibody - based assay that we have developed is highly effective in detecting both recent and past Zika virus infections and in discriminating Zika from other flavivirus infections,» said Davide Corti, senior vice president and chief scientific officer of Humabs BioMed.

Further, current serologic tests often can't distinguish between related flavivirus infections in dengue - endemic regions.

According to the researchers, this latest work may now open new possibilities for intervention in flavivirus infection.

However this is the first report of flavivirus infection in ducks with a severe outcome and the future implications of such findings should be heeded.

The high selectivity, and the potency with which some of these receptors promote flavivirus infection, suggest only a small number of receptors might be effectively targeted to treat these diseases.

Fifth, some mother - infant pairs demonstrated laboratory evidence of an unspecified flavivirus infection; therefore, some of these might not have had Zika virus infections.

Not exact matches

Furthermore, the defects observed are specific to an infection by ZIKV, as other neurotropical viruses of the flavivirus family (West Nile virus, yellow fever,...) did not cause microcephaly, in contrast to Zika virus.

It notes some of the critical scientific questions regarding Zika that deserve further exploration, including: whether certain viral mutations occurred to facilitate its geographical spread; if different species of Aedes mosquitoes are capable of transmitting Zika and what that may mean for future transmission; what is apparently unique to Zika compared to other more well - known flaviviruses, such as dengue, that can explain why it can cause congenital infections, neurological conditions and encephalitis, transmit sexually and persist for long periods of time in multiple parts of the human body; and whether preexisting immunity to other related flaviviruses may impact Zika exposure and infection.

«Most flaviviruses are zoonotic,» meaning they can be transmitted from animals to people, Gao says, «so infection of human beings can not be ruled out.»

«Infection model developed for tickborne flaviviruses.»

Assays already exist to detect Zika virus infection, but they either work only shortly after infection or are poor at differentiating Zika from other flaviviruses.

As of 30 November, more than 1200 cases had been reported in 10 states, all of which have also reported Zika virus infections, says Ana Maria Bispo de Filippis, head of the flavivirus laboratory at the Oswaldo Cruz Institute in Rio de Janeiro, Brazil.

«Prior dengue or yellow fever exposure does not worsen Zika infection in monkeys: Findings counter some concerns that prior flavivirus disease primes immune system to enhance Zika infection.»

Dengue virus and Zika virus are both positive - strand RNA flaviviruses, which means that once a virus particle infects a cell, its RNA genome can be immediately translated by cellular machinery into viral proteins to make new virus particles and spread the infection.

In this way, the flaviviruses clamp down on the cell's responses to thwart infection, including deploying antiviral proteins.

We performed a systematic investigation, from epidemiology, pathogen isolation, virus characterization, disease reproduction by infection with the isolated virus (fulfilling Koch's postulates), to virus genome sequencing and found that the duck egg drop disease was caused by a new flavivirus, BYD virus, that is closely related to Tembusu virus.

This new research tool (Figure 2) allows for the rapid analysis of biological specimens (serum, plasma, CSF, etc.) for high - throughput discovery of biomarkers that may be able to discriminate between these two very similar flaviviruses in a larger window after initial infection than currently possible.

His research includes (i) the molecular epidemiology and epidemic history of HIV and hepatitis C, particularly in Asia and Africa, (ii) the global evolution of influenza viruses, (iii) virus and immune dynamics during chronic viral infection, (iv) the evolution of flaviviruses, and (v) the development of new techniques for tracking and predicting virus transmission.

So far there are no reports of the Zika virus entering the U.S. blood supply, but the FDA writes that «the risk of blood transmission is considered likely based on the most current scientific evidence of how Zika virus and similar viruses (flaviviruses) are spread and recent reports of transfusion - associated infection outside of the U.S.»