By using fruit
fly as a model system, Minna Poukkula working at the Institute of Biotechnology, University of Helsinki, has found out how actin - rich protrusions contribute to cell migration in animal tissues.
Not exact matches
And we've learned a lot about that in
model systems, such
as in fruit
flies, worms, and mice.
But
as the first compact robot that can both climb and
fly, it has practical uses too, such
as gathering aerial footage for 3D
modelling systems.
Enormous projects such
as ENCODE (for humans and mice) or modENCODE (for other lab
model systems, such
as the
fly Drosophila or the worm C. elegans) have been devoted to collecting these data in order to analyse and interpret them in the framework of genomic data and to form hypotheses about functions and relations.
«Studying these effects in
model systems such
as rats and
flies allows us to address these questions by manipulating the likely mechanisms involved, which we can't do in humans.»
The research group, led by Erika Matunis, Ph.D., a professor of cell biology at the Johns Hopkins University School of Medicine, has been using the fruit
fly as a
model living
system in which to study stem cells in their natural state.
«This experiment will help reveal the short - and long - term effects of space travel on the cardiovascular
system, using fruit
flies as a
model.
Model systems, such
as the mammalian gut bacterium E. coli for microbiology and the fruit
fly for biomedicine, have been invaluable for deciphering complex biology.
Lindquist, who started
as a fruit
fly cell biologist, now tracks warped proteins and their consequences through
model systems spanning millions of years of evolution
«It validates the approach of using even very distant
model systems, such
as the
fly, to study human biology.
The experts explain that many of the state - of - the - art technologies are required to tease out relevant information from
model systems, whether these be organoids or «classical animal
models such
as the fruit
fly, zebra fish or mouse,» adds Milán.