Not exact matches
He and his team at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany
used fruit
flies to explore how epigenetic modifications are transmitted from the mother to the
embryo.
Therefore the researchers
used a variety of genetic tools in fruit
flies to remove the enzyme that places H3K27me3 marks and discovered that
embryos lacking H3K27me3 during early development could not develop to the end of embryogenesis.
The researchers
used this live - imaging technique to study
fly embryos at a key stage in their development, approximately two hours after the onset of embryonic life where the genes undergo fast and furious transcription for about one hour.
(Drosophila, or fruit
flies, are a frequently
used model for understanding human disease, and oskar is critical for normal development of fruit
fly embryos.)