«Plants modified to express fruit
fly gene used to detoxify contaminated land.»
Not exact matches
Gene drives enable a gene to spread rapidly through a population; there are plans to use them to combat mosquito - borne diseases by making the flies sterile or unsuitable as hosts for various viruses and parasi
Gene drives enable a
gene to spread rapidly through a population; there are plans to use them to combat mosquito - borne diseases by making the flies sterile or unsuitable as hosts for various viruses and parasi
gene to spread rapidly through a population; there are plans to
use them to combat mosquito - borne diseases by making the
flies sterile or unsuitable as hosts for various viruses and parasites.
«Our study validates
using fruit
flies as a model to discover new
genes that may also control aggression in humans.»
NASA astronaut Peggy Whitson performed the
Genes in Space - 3 investigation aboard the space station
using the miniPCR and MinION, developed for previously
flown investigations.
Most of the rechristened
genes were identified by geneticists studying the fruit
fly; when equivalent
genes were later found in the human genome, researchers simply continued
using the name of the fruit
fly gene to avoid confusion.
To identify
genes involved in the patterning of adult structures, Gal4 - UAS (upstream activating site) technology was
used to visualize patterns of
gene expression directly in living
flies.
Collins and Anthony James of the University of California, Irvine, thought they might
use the mutant bug to test a fancy trick: Take a bit of DNA, called a transposon, that likes to wiggle into genomes, and
use it to insert a fruit
fly gene for darker eye color into a mosquito's DNA.
Already, researchers have
used CRISPR / Cas9 to edit
genes in human cells grown in lab dishes, monkeys (SN: 3/8/14, p. 7), dogs (SN: 11/28/15, p. 16), mice and pigs (SN: 11/14/15, p. 6), yeast, fruit
flies, the worm Caenorhabditis elegans, zebrafish, tobacco and rice.
The technology has been developed in recent years in fruit
flies, mosquitoes and other organisms,
using CRISPR
gene editing.
«I'm not
used to that kind of conference,» says Messer, who says he told the group about his lab's efforts to study the evolution of resistance to CRISPR
gene drives in fruit
flies.
Prof. Hasan's work
used Drosophila
flies with mutated Orai
genes that prevented normal operation of the SOCE process.
Decades of work in developmental biology have provided a start: Biologists have
used mutant frogs,
flies, mice, chicks, and fish to identify some of the main
genes that control a developing cell's decision to become a bone cell or a muscle cell.
The study, conducted
using fruit
fly populations bred to model natural variations in human sleep patterns, provides new clues to how
genes for sleep duration are linked to a wide variety of biological processes.
More than two decades ago, in one of the first papers
using gene sequences to find signatures of natural selection, scientists hypothesized that a molecular change in an enzyme gave the Drosophila melanogaster fruit
fly species its superior ability to metabolize alcohol.
It did not begin to seriously discuss the risks associated with
using the approach to engineer
genes that could quickly spread through wild populations — known as
gene drives — until after experiments demonstrating the concept in fruit
flies had been published in a peer - reviewed journal (V. M. Gantz & E. Bier Science 348,442 — 444; 2015).
Using a
gene from fruit
flies, scientists have produced the most resilient and stretchy rubber known.
By
using insect activity monitors, the scientists assessed the effects of drug and
gene therapy candidates on the
flies» ability to move.
They tested this theory in mice, rats,
flies and fish
using publicly available
gene - expression data.
Keene and his collaborators
used fruit
flies in their study and created various scenarios between sleeping and foraging to test each
gene one at a time to determine which
gene didn't affect their sleep.
Using the Drosophila melanogaster fruit
fly as a model organism, the team led by Prof. Dr. Ingrid Lohmann at Heidelberg University's Centre for Organismal Studies was able to show how a special developmental
gene from the Hox family influences germline stem cells.
Using experiments with fruit
fly eggs, the team saw that Oskar binds to RNA within the cell — specifically three RNAs derived from
genes also known to be important to germline development.
The
gene expression patterns were so similar, in fact, that investigators were able to
use them to match up the stages in worm and
fly development.
This visual abstract of Mohammad et al. depicts how mammalian anxiety factors also govern defense behaviors in the
fly and
use these behaviors to identify new conserved candidate anxiety
genes.
In 2004 Guilherme Neves and Andrew Chess, now at the Center for Human Genetic Research at Massachusetts General Hospital, tracked the roles played by other
genes on chromosome 21 — in this case
using a fruit
fly as the model.
The Science paper, by developmental biologist Ethan Bier and his student Valentino Gantz at the University of California, San Diego,
used CRISPR to insert a modification into
genes on both chromosomes in a pair, so that when the
flies bred, they would pass the modification on to practically all of their offspring.
In order to find the
genes that guide that migration, geneticist Ruth Lehmann of the Howard Hughes Medical Institute at New York University Medical School and her colleagues
used chemicals to cause mutations in thousands of adult fruit
flies then screened their embryonic offspring for lost or misguided germ cells.
To do this, they
used specially bred
flies with
genes that could be turned off in groups of nerve cells at high temperature.
It will also be
used to analyse
gene signalling networks in cress, fruit
flies and sea urchins.
To see how courting is affected when neurons are hyperactivated, they
used flies with a version of a
gene that was stuck in the «on» state in clumps of nerve cells.
To see what
genes might be involved in this increased aggression, the team
used microarrays to look for differences in
gene expression in
fly brains.
«Precise
gene - editing techniques could be
used to tailor - make
flies that express a patient's specific genetic mutation.
The researchers
used this live - imaging technique to study
fly embryos at a key stage in their development, approximately two hours after the onset of embryonic life where the
genes undergo fast and furious transcription for about one hour.
In spite of the difference between the cell functions responsible for giving rise to a tumour and for the metastasis of this same tumour, studies at IRB Barcelona
using the
fly Drosophila melanogaster reveal that some
genes can drive both phenomena.
The research team led by Han
used high - throughput techniques to alter the activity of dozens of
genes in
flies» hearts simultaneously in order to validate
genes that cause heart disease.
In the study, Spradling, with colleagues Michael Buszczak and Shelley Paterno, determined that the fruit
fly gene scrawny (so named because of the appearance of mutant adult
flies) modifies a specific chromosomal protein, histone H2B,
used by cells to package DNA into chromosomes.
Using fruit
flies as their favored experimental model, the Jans pulled back the curtain on a graceful symphony of steps guided by a succession of
genes that influences the onset and course of neural development and wiring.
They chose fruit
flies because
flies and humans
use many of the same
genes, but the genetic makeup of
flies is much simpler and the short life cycle of
flies better assists scientists in conducting genetic experiments, Panin said.
Instead of focusing on marine animals, they
use animal models such as freshwater zebrafish, salamanders, fruit
flies and nematode worms that share many of their
genes with humans.
Yeast, bacteria, worms, and
flies had long been
used for
gene knockout studies, and mice with knockout
genes had just been developed before Waldman began his experiments.
Yeast, bacteria, worms and
flies had all long been
used for
gene knock - out studies, and mice with knock - out
genes had just been developed before Waldman began his experiments.
The authors had
used a controversial new molecular technique to try to force a certain
gene to be inherited by all of a fruit
fly's offspring.
«Maybe it's in my
genes, because my father
used to be a pilot, but I love
flying and traveling.
Using the fruit
fly Drosophila, a standard lab model for studying animal biology, the researchers discovered a cascade of molecular signals that program
gene activity to drive the
fly from one stage of maturation to the next, like a baby turning into an adult.