Sentences with phrase «focused on chromatin»
Over the years his research has focused on chromatin structure, its modifications and their role in gene regulation, and he has partnered to publish, in his career, over 153 papers.
http://www.nationalpostdoc.org/
Cancer studies have increasingly focused on chromatin — the intertwined proteins and DNA that are packaged into chromosomes — because of its ability to regulate genes important for either activating or inhibiting tumorigenesis.
Not exact matches
«We may need to focus on drugs that modify chromatin in a way that decreases methylation,» Grayson says, to «turn on genes that are missing in the schizophrenia.»
The initial work was mainly focused on the study of the regulation of muscle chromatin and gene expression by motor innervation.
The laboratory's interest is the stress response and the interplay between DNA repair and other cellular processes including transcription and chromatin remodeling, and is focused on elucidating the function and mechanochemistry of DNA - based motors using a combination of biochemical, biophysical and structural techniques.
The CCP also focuses on deciphering the regulatory circuit that controls chromatin organization and maintenance in various stem cell types to determine their functional influence on a cell expression signature and phenotype.
We focus on how changes in chromatin structure orchestrate the developmental transitions from fertilization to genome activation to cell fate specification.
Our laboratory will focus on applying new synthetic and chemical biology methods to understand chromatin structure and function.
Steve's research focuses on polyploid crops where he uses genomics and bioinformatics approaches to examine chromatin structure and the effect it has on gene regulation.
In order to address this question, we focus on the Nodal signaling pathway and analyze the chromatin profile of its target genes during the transition from pluripotency to fate specification.
My lab is focused on investigating the mechanisms by which chromatin modifier gene mutations contribute to the initiation and progression of urothelial carcinomas of the bladder and upper tract.
His laboratory focuses on the roles of reversible protein modifications that are involved in modulating signal transduction, chromatin dynamics and gene activation.