Sentences with phrase «focused on genes»
Several laboratories that explore such epigenetic processes have productively focused on genes in the glucocorticoid system (19 ⇓ — 21).
http://www.pnas.org/
The Utah research focused on genes found in mitochondria — the power plants of cells — and that mutate at a high rate, acting like a clock to reveal when evolutionary events happened.
He is head of the collection of EMBL - EBI resources focused on Genes, Genomes and Variation and in this role provides strategic leadership of the six faculty groups that together provide all of EBI's genome annotation resources.
Because elevated blood levels of the neurotransmitter serotonin have long been associated with this disorder, the researchers focused on the genes that regulate the production and function of this powerful chemical messenger.
In their case, they focused on genes in the brain that play a role in behavior and mental health.
The analysis focused on the genes involved in nitrogen fixation and the formation of heterocysts, which are special cells where atmospheric nitrogen is converted into ammonia.
In their quest to decipher the complex code of autism, which can run in families, most scientists have focused on genes.
When they focused on genes involved in drug resistance, the group found that C. krusei differs from C. albicans; many of the sites that are often mutated in the target of azole drugs in resistant C. albicans are not mutated in C. krusei.
Most of the work initially focused on the genes that behavioral geneticists call the «usual suspects» — and it paid off.
Zika induced changes that were more focused on genes involved on DNA replication and repair, indicating that Zika infection disrupts cell replication more.
After reporting second - quarter results that contained upbeat clinical news, Spark Therapeutics (NASDAQ: ONCE), a clinical - stage company focused on gene therapy, rose 18 % as of 12:30 p.m. EDT on Wednesday.
To receive funding from Safe Genes, teams focused on gene - drive technology must work on controls plus at least one of the program's other focus areas — remediation or inhibitors.
In his «lessons learned» article, Wilson advises researchers against putting themselves in situations that might create potential financial conflicts (in 1992 Wilson had founded a biotechnology company focused on gene therapy).
To figure out the mechanism, Nadeau focused on the gene Foxp3, which spurs immature T cells to develop into those police officer cells, T - regs.
The researchers focused on a gene located on chromosome 15, which was previously shown to impact protein concentration.
The researchers decided to focus on genes that have been linked to asthma risk.
By focusing on these genes that are «awakened» in tumors, the researchers have shown that in almost all cancers, tens of specific genes in the germline and the placenta are aberrantly activated.
Holt, with first author Charles Askew and colleagues at École Polytechnique Fédérale de Lausanne in Switzerland, focused on a gene called TMC1.
Research into the drivers of genetic diversity has largely focused on gene expression, which controls how much of a given protein will be made, when, and in what tissue.
The researchers focused on the gene IRF6, the gene most commonly associated with cleft lip or palate.
Most current research into the causes of cancer focuses on genes and environmental triggers.
Most DNA research focuses on genes that contain encrypted messages for making proteins, the cellular workhorses essential to life.
Anderson and colleagues focused on the gene UBE3A, multiple copies of which causes a form of autism in humans (called isodicentric chromosome 15q).
The researchers also collected blood for a genetic analysis, focusing on a gene known as BDNF (brain - derived neurotrophic factor).
The team studied the genomes of almost 8,000 child and parent trios, focusing on genes that coded for proteins as well as non-coding parts of the genome that control the switching on and off of genes, known as regulatory elements.
Out of 129 possible cancer drivers, iCAGES focused on a gene called ARAF.
New research into the causes of this baffling disorder is focusing on genes that control the development of the brain
«Everyone was focusing on genes expressed in the brain,» says Levitt, «but this gene is important for repair of the intestine and immune function.
Niakan's group focused on a gene called OCT4 (also known as POU5F1), a master regulator of gene activity, which is important in mouse embryo development.
«These findings suggest that focusing on genes with conserved expression levels among primates may be helpful in identifying promising candidates for disease - association studies,» the researchers write.
Studying embryos of the little skate, Gillis focused on the gene Sonic hedgehog, which produces a signaling protein whose function is well understood in the mammalian limb.
Some scientists have criticized TCGA for focusing on gene sequencing while diverting funds from functional studies that can determine which of the hundreds of mutations are most important.
They focused on a gene linked to more than 50 % of long QT syndrome cases that codes for a protein called KCNQ1, which is part of a potassium channel.
Several more projects explicitly focus on gene drive applications: A group at UC Riverside led by molecular biologist Omar Akbari will try to document the genetic diversity of the Aedes aegypti mosquito and test ways to limit or reverse gene drives in contained test environments.
In order to focus on genes that share similar biological processes and correlate with the calcification process, the analysis continued for unique up - regulated gene transcripts and total up - regulated gene transcripts that were differentially expressed during daytime (437 genes for unique and 1,333 for total), and during night - time (267 genes for unique and 1,171 for total).
His academic research focused on gene regulation and signal transduction mediated by ion channels and G proteins.
Their work focusses on the genes that regulate the entry of cells into the myogenic programme.
At Emory, the labs of Stephen Traynelis and Hongjie Yuan have published an analysis of ExAC data, focusing on the genes encoding two NMDA receptor subunits, GRIN2A and GRIN2B.
Ultimately, the combination of this new method of focusing on gene activity in single cells with other single - cell techniques involving microscopic imaging is likely to reveal the origins of developmental disorders of the brain, he added.
Dr. Funke describes next - generation sequencing (NGS) with a focus on gene panel testing for inherited conditions.
Through this process, the scientists were able to narrow their search and focus on the genes that were both mutated in head and neck cancer and hijacked by HPV.
Much of the post-HGP focus has fallen on genes, spurring new discussions of how heredity works and causing scientists to look at DNA differently, setting aside the traditional focus on genes as the dominant actors within DNA.
Our computational biology research programme focuses on gene expression regulation and the mechanisms by which it can be disrupted in human diseases such as cancer.
For example, in contrast to genetics, which focuses on single genes, genomics focuses on all genes (genomes) and their inter-relationships (see WHO definition).
Babies in the sequencing arm who have, or develop, health conditions that may have an underlying genetic cause may also receive an «Indication - Based Analysis» that can re-examine the baby's sequencing information, with a specific focus on genes that have previously been associated with the baby's specific health condition.
He focused on gene regulation at the transcriptional level during his postdoc.
The Lexicon efforts are focused on gene families that are pharmaceutically important, such as transporters, G - protein coupled receptors (GPCRs), ion channels, kinases and other key enzymes, membrane proteins (e.g., receptors), and secreted proteins.
His present research focuses on gene transcription and gene therapy for AIDS and cancer.
The Dockrell group is focusing on genes and cells that play a crucial role in polarisation of the immune responses and that could affect vaccine efficacy.
Her laboratory also uses mouse models to study other neurogenetic diseases, such as schizophrenia and ALS, with a focus on genes that affect the course of disease and clinical outcomes.