Sentences with phrase «focused on these antibodies»

The team focused on these antibodies, which together target the two types of influenza viruses that contain all strains known to cause disease in humans.

Flavell's research team focused on antibody coatings on the surface of bacteria.

«Our study acknowledges the importance of T cells in an environment where most people are focused on antibodies,» says the study's senior author, Sujan Shresta, Ph.D., an associate professor in the Center for Infectious Disease.

Resources can then be focused on those antibodies shown to be highly specific to your targets of interest.

His research was focused on antibody affinity, measles, RSV and epitope - based vaccines.

Not exact matches

Prior to Sucampo, he served as Chief Scientific Officer of Ambrx Inc., a clinical - stage biopharmaceutical company focused on the development of antibody - drug conjugates (ADCs) that was acquired by a consortium led by Fosun Pharmaceutical Group in 2015.

• Arsanis, a Waltham, Mass. - based clinical stage biopharmaceutical company focused on monoclonal antibodies, raised $ 40 million in an offering of 4 million shares at $ 10 a piece, below its $ 15 to $ 17 range.

In its latest study published in a special section of the Journal of AOAC International focusing on food allergens and gluten, GIG said obtaining representative test samples for antibody - based testing (traditional way for testing gluten) is challenging when analyzing whole grains for gluten.

Macrogenics, a biopharmaceutical company, is focused on discovering and developing innovative antibody - based therapeutics for the treatment of cancer, as well as various autoimmune disorders and infectious diseases.

That development is important because a T cell response will likely confer longer - term protection than current inoculations do and defend against a variety of flu strains (because T cells would be on the lookout for several different features of the flu virus whereas antibodies would be primarily focused on the shape of a specific strain).

Most groups have focused on detecting proteins released from dying brain cells, but those proteins are not always abundant after injury and often require exotic or proprietary antibodies to measure, said study corresponding author Adam Chodobski, associate professor (research) of emergency medicine in the Alpert Medical School of Brown University.

Schering - Plough, for example, merged two of its California research facilities in 2005 to create a new unit in Palo Alto that focuses on monoclonal antibodies and other therapeutic proteins.

At Rinat, Van Blarcom focuses on designing, building, and using sequence libraries to discover more effective antibodies.

Within a company, you're likely to specialize, since most companies are focused on a narrow area of science (i.e., therapeutic human monoclonal antibodies).

The pair focused on the monoclonal antibody canakinumab, already approved for juvenile arthritis, because it selectively targets a molecule called IL - 1β, which is part of the pathway driving atherosclerosis.

In collaboration with the Vall Hebrón Oncology Institute (VHIO), they are now focusing on binding a peptide to a therapeutic antibody to treat glioblastoma — the most aggressive brain cancer in adults.

She helped lead a GSK project focused on designing a monoclonal antibody to link to the HER3 receptor on human cells as a treatment for cancer.

Since IgAs are notoriously hard to work with, the researcher believes future research should focus on developing antibodies that are easier to produce and can be tested in mice.

Until now, most researchers have focused on one of two strategies: attacking tumors with antibodies, which activate the innate immune system, or stimulating T cells, which form the backbone of the adaptive immune system.

The bispecific antibodies focus on the CD3 receptor for two reasons.

Furthermore, these antibodies prevent CHIKV from both entering and exiting cells, whereas prior studies of neutralizing antibodies to CHIKV and multiple other classes of viruses have focused on the capacity to block viruses from entering a cell.

The company was largely focussed on the generation of proteins, including therapeutic antibodies, in potato plants.

«Currently, there is a lot of focus on the use of antibodies transferred passively or through a vaccine to prevent infection in infants, however this study cautions against that and suggests that broadly neutralizing antibodies may actually aid in enhancing transmission from mother to child,» added Sagar, an attending physician in infectious diseases at Boston Medical Center.

Future research should focus on how the resident memory T cells work with memory B cells that produce antibodies against viruses and bacteria, he suggests.

Proteomics (Fagerberg et al, «Analysis of the human tissue - specific expression by genome - wide integration of transcriptomics and antibody - based proteomics») with a focus in the article on the tissue - specific pattern in the human body.

Dr. Schief's work focuses on computation - guided and structure - based design of immunogens and immunization regimens, with the goal of inducing broadly neutralizing antibodies against HIV and other pathogens that have frustrated traditional vaccine design strategies.

GigaGen focuses its activity on discovering new biological treatments by using antibodies derived from millions of cells within immune repertoires.

Dr. Polonis» lab has focused for many years on functional antibodies elicited by natural infection and by vaccination, utilizing samples from multiple natural history cohorts and vaccine studies; her lab is currently performing an extensive analysis of pseudovirus neutralizing antibodies in the large RV144 follow - on trial, RV306.

With investigators and clinicians from the Wistar Institute, University of Pennsylvania, Merck Pharmaceuticals, and Philadelphia FIGHT, Objective 2 (IRF2) focuses on stimulating the immune system with which we are all born (innate immunity), through a combination immunotherapy approach using highly - potent antibodies against HIV, together with pegylated interferon alpha 2b.

For more than 25 years, Dr. Levy's research has focused on monoclonal antibodies and the study of malignant lymphoma, currently using the tools of immunology and molecular biology to develop a better understanding of the initiation and progression of the malignant process.

iTeos has a broad pipeline focused on multiple complementary mechanisms of action including small molecules targeting IDO1, A2A, and STING as well as antibodies directed to TIGIT and Galectin 3.

Made major contributions to the field of immunology through his studies on immune tolerance in animal models, with particular focus on transplantation tolerance and autoimmunity, in addition to pioneering the use of therapeutic monoclonal antibodies against T cells, resulting in the development of Campath - 1H, the first humanised monoclonal antibody to be used therapeutically.

My early work focused on understanding the residual risk of HIV infection from transfusions after implementation of HIV antibody screening in 1985.

Recent work has contributed to the characterization of antibodies that inhibit Chikungunya virus infection and current work is focused on Zika virus.

Therefore, my research has been focused on engineered antibody for therapeutic and diagnosis purpose in dengue and zika infectious diseases.

Dr. Matyas» research efforts on HIV have focused on developing immunization formulations that would induce antibodies similar to the broadly neutralizing antibodies 2F5 and 4E10, which bind to the both gp41 and membrane lipids.

This inspired her to complete her Ph.D. with a focus on antigen recognition by antibodies.

Unlike more traditional therapeutic modalities such as small molecules or antibodies, Neurona is focused on unique compositions of cells that can be precisely targeted, integrated into damaged neural circuits, and provide activity - dependent regulation.

Vaccination is an attractive disease - prevention strategy, and leading candidates focus on the induction of bactericidal antibodies.

Current research applications focus on new approaches to a) drug and probe development for neurodegenerative disorders and diseases including Schizophrenia, Alzheimer's, and Parkinson's, b) understanding the structural determinants of antidepressant binding to neurotransmitter transporters, c) cardiac arrhythmia as caused by the complex interplay of potassium channel regulation and drug interactions, d) multidrug resistance in cancer and bacterial cells related to multidrug transporter proteins, and e) structural basis of viral infections and antibody activity.

Immunotherapeutic concepts to target acute myeloid leukemia: focusing on the role of monoclonal antibodies, hypomethylating agents and the leukemic microenvironment

I was also happy to see that this particular doctor was thinking beyond synthetic thyroid medications and focused on thyroid antibodies when he stated «Thyroxine does not normalize symptoms or anti-thyroid peroxidase levels» during his presentation at the 2015 International Thyroid Congress.

The antibody reaction of study subjects came as a surprise to researchers since treatment for celiac disease has historically focused on gluten.

Plc is a clinical stage biotechnology company, which focuses on the discovery, development and commercialization of novel antibodies for the potential treatment of diseases that involve protein misfolding or cell adhesion.

GREENFIELD, IND. (January 25, 2018)-- Elanco Animal Health, a division of Eli Lilly and Company (NYSE: LLY), is pleased to announce a new global in - licensing agreement with Ab E Discovery to further develop and bring to market an egg antibody focused on supporting gut health, and thereby the growth and welfare, of poultry.

Mg Biologics is a licensed antibody manufacturer, focusing on antivenin products in the small animal industry.

The study is the first to focus on the links between antibody responses to cockroach and mouse proteins and respiratory and allergic symptoms in such a young age group, and the implications for children who live in our inner cities where indoor air quality is often poor are truly significant.

Represents various clients developing biologic therapeutics (both antibody - based and cellular), with particular focus on counseling with respect to freedom to operate while also securing strong protection, worldwide, for assets, including those whose major uses are likely to be in combination and / or in specialized patient populations.

About Blog Oxford Protein Informatics Group is a research group in the Department of Statistics at the University of Oxford focusing on aspects of protein modelling, homology modelling, membrane proteins, sequence alignment, antibodies, and drug discovery.