Sentences with phrase «focusing on brain cells»

Not exact matches

Mishra's team focused on a neurotransmitter called brain natriuretic peptide (BNP), which is expressed in a small number of sensory nerve cells or neurons.

Most groups have focused on detecting proteins released from dying brain cells, but those proteins are not always abundant after injury and often require exotic or proprietary antibodies to measure, said study corresponding author Adam Chodobski, associate professor (research) of emergency medicine in the Alpert Medical School of Brown University.

Faced with the complexity of the brain, neuroscience focused on questions that could be subdivided into manageable units: How we see, how we move, how nerve cells work.

Neuroscience focused on the nuts and bolts of the brain: how nerve cells communicate with electrical and chemical pulses, how brains learn and calculate and remember.

Stem cells have long been heralded as a potential treatment for a range of brain ailments, but research has so far focused on movement disorders such as Parkinson's disease.

The cerebellum is the part of the brain responsible for posture, balance and movement, and the researchers focused on those cells that control blinking.

The study, to be published Aug. 22 in the journal Cell Reports, focused on the action of serotonin, an important neuromodulator in the brain.

The findings, which focused on support cells in the brain called astroglial cells, appear online today in Nature Communications.

Their analysis focused on the substantia nigra, a brain structure where Parkinson's disease kills neurons that use the chemical dopamine to communicate with other cells.

Because of the strong association between hippocampal cell growth and exercise in models, previous work on exercise and the brain has not focused on the entorhinal cortex, despite its critical role in learning and memory until now.

In the new study, the team focused on neurons called amacrine cells and horizontal cells, which have a known role in «preprocessing» — or adjusting — electrical signals transmitted to the brain from the photoreceptors after they have been stimulated by light photons.

The Loyola study focused on how these misfolded protein clumps invade a healthy brain cell.

The research effort he directs focuses on entirely new compounds that might slow the loss of brain cell connections, which may play a role in schizophrenia biology.

His research largely focuses on new means to incorporate imaging methods to view cells of brain tumors with a hand held instrument that a neurosurgeon can use to visualize the individual cells during the progress of the operation.

The projects vary slightly in their aims — the US BRAIN initiative will start by cataloguing the types of cells in the brain and how they wire together, while the China Brain Science Project is focused on developmental, psychiatric and neurodegenerative disorBRAIN initiative will start by cataloguing the types of cells in the brain and how they wire together, while the China Brain Science Project is focused on developmental, psychiatric and neurodegenerative disorBRAIN initiative will start by cataloguing the types of cells in the brain and how they wire together, while the China Brain Science Project is focused on developmental, psychiatric and neurodegenerative disorbrain and how they wire together, while the China Brain Science Project is focused on developmental, psychiatric and neurodegenerative disorbrain and how they wire together, while the China Brain Science Project is focused on developmental, psychiatric and neurodegenerative disorBrain Science Project is focused on developmental, psychiatric and neurodegenerative disorBrain Science Project is focused on developmental, psychiatric and neurodegenerative disorders.

«Previous studies primarily focused on neurons and the retinal pigment epithelium cells as culprits in degeneration,» said Eroglu, who is also a member of the Duke Institute for Brain Sciences (DIBS).

The study focused on the serotonin transporter, a molecule that regulates the amount of serotonin signaling between brain cells and is a major target for treatment of depression and mood disorders.

In trying to understand the brain, for instance, neuroscientists have focused on synapses — the junctions between nerve - cell endings — as the essential transmitters of thought and feeling.

Past research has focused on prevention of the disease by reducing the levels of proteins that cause brain plaques and tangles and kill nerve cells.

The work, which appears in the journal Cell, focuses on the regulation of «neuronal plasticity» — changes in neuronal structure — and its function in the brain.

Whereas traditional MS medications target the immune system's T - cells, ocrelizumab focuses on destroying the system's B - cells, which fuel the brain inflammation that causes the disease to worsen.

«This study focused on the development of the neocortex, but we aim to analyze multiple brain regions and developmental stages to achieve a more comprehensive atlas of cell types in the developing human brain,» Kriegstein said.

They focused this effect on the hypocretin neurons, which are brain cells in the lateral hypothalamus.

In the present work, the teams led by Michael Ewers (ISD) and EMBO Member Christian Haass (DZNE) focussed on the TREM2 protein, which functions in specialized brain immune cells called microglia that clear toxic material resulting from nerve cell injury.

In a study published in the Journal of Clinical Investigation, researchers looked at how immune cells reached the myelin, focusing on the barrier between brain tissue and the rest of the body.

The screening revealed coibamide A to be capable of killing many types of cancer cells, but Ishmael decided to focus subsequent studies on two types in particular — brain tumors, or glioblastomas, and a breast cancer subtype known as triple negative breast cancer.

Researchers focused on injury to cells in the peripheral nervous system (PNS)-- the crucial network of nerves outside the brain and spinal cord.

Ron McKay and his colleagues at the National Institute of Neurological Disease and Stroke in Bethesda, Maryland, usually focus on brain development, but they were intrigued by recent papers reporting that some pancreas cells express nestin, a protein typical of developing neural cells.

Because stem cells have the ability to develop into many different cell types in the body, researchers at USF's Center of Excellence for Aging and Brain Repair, Department of Neurosurgery & Brain Repair have focused on using stem cells to restore function lost through neurodegenerative disorders or injuries.

«For many years, the focus has been on finding drugs that block channels and receptors in the brain that affect the way signals are made between cells.

Much of the bioethics focus has been on what would happen if an animal had enough human brain cells to think and feel like a person — but a person inside the body of a monkey, pig, rat, or mouse.

Then I will present you work mostly from my own group, which has focused since quite some time on the possibility of converting cells present in the brain into neurons.

She studies the process of cancer initiation and progression along with cancer stem cells, the evolution of drug resistance and the dynamics of metastasis formation focusing on lung, brain, breast and pancreatic cancers.

His laboratory focuses on lineage progression of adult neural stem cells and on direct conversion of brain resident cells into induced neurons.

The work of his laboratory focuses on lineage progression of adult neural stem cells and on direct conversion of brain resident cells into induced neurons.

NeuroStemcell is focused on the identification and systematic comparison of progenitor cell lines with the most favourable characteristics for mesDA and striatal GABAergic neuronal differentiation, generated either directly from human embryonic stem (ES) cells, from Neural Stem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals models.

Ultimately, the combination of this new method of focusing on gene activity in single cells with other single - cell techniques involving microscopic imaging is likely to reveal the origins of developmental disorders of the brain, he added.

The focus now is on getting better at growing the cells and turning them into the right kind of brain cell before starting new trials in patients.

Their image, showing six different computational visualizations of a cell membrane for a single brain cell, was featured as the cover story in a special issue of Biophysical Journal, that focuses on brain biophysics and is published by the Biophysical Society.

Currently, her research interest is focused on the functional characterization of cell - autonomous molecular determinants, known to control cardinal stem cell properties in normal NSCs, in the attempt of understanding their putative role in regulating the same properties in brain tumor - derived cancer stem cells.

For the first 20 years of his career, Dr. Anderson's research focused on the biology of neural stem cells and their role in brain development.

However, instead of concentrating on the neurons themselves, she focuses her research on the network surrounding and supporting the cells: the brain's vascular and immune system.

The Swedish part of the effort, called the Human Developmental Cell Atlas (HDCA) program, includes researchers from Karolinska Institutet, Stockholm University and KTH, focusing on brain, lung, heart and fetal development during the first 12 -LSB-...]

Caspi and Moffitt built on earlier research focusing on a variation in a gene called the serotonin transporter, which normally helps information flow between nerve cells in the brain.

What could medicine look like someday if, instead of focusing primarily on the organ affected by a disease — neurologists examining brain diseases, pulmonologists focusing on lung diseases — our system was centered on how cells process energy?

Three recent experimental studies focused on low consumption / exposure.949596 In one study, 29 smokers each consumed a single cigarette, immediately after which they had a significant decrease in blood vessel output power and significant increase in blood vessel ageing level and remaining blood volume 25 minutes later, as markers of atherosclerosis.94 In another study, human coronary artery endothelial cells were exposed to the smoke equivalent to one cigarette, which led to activation of oxidant stress sensing transcription factor NFR2 and up - regulation of cytochrome p450, considered to have a role in the development of heart disease.95 These effects were not seen when heart cells were exposed to the vapour from one e - cigarette.95 A study exposed adult mice to low intensity tobacco smoke (two cigarettes) for one to two months and found adverse histopathological effects on brain cells.96

The researchers» goal was to correct the faulty NPC1 gene in as many cells and organs as possible, with a strong focus on the brain.

His ADA presentation will focus on how nutrient - sensors that control the balance between energy - consuming and energy - producing processes in almost every cell in our bodies also play a very specific role in the brain.

Specifically, one speaker focused on ways to increase brain - derived neurotrophic factor (BDNF)-- a protein that may «stimulate the production of new brain cells and / or strengthen existing ones.»

In this episode Rhonda talks about how heat stress from using the sauna makes the body more resilient to the stresses of aging, possible reasons why one study associated sauna use with up to a 40 % lower all - cause mortality as well as a 50 % lower cardiovascular disease related mortality, how it enhances athletic endurance, staves off muscle atrophy, improves regrowth of muscle after disuse, and some of the profound effects on the brain, including the growth of new brain cells, improvement in focus, learning, and memory, and even potentially ameliorating depression and anxiety.