Sentences with phrase «focusing on clinical trial»

One report, focusing on clinical trial patients with advanced kidney cancer treated with checkpoint inhibitors, is from scientists at Dana - Farber Cancer Institute and the Broad Institute of MIT and Harvard, led by Eliezer Van Allen, MD, of Dana - Farber and the Broad, and Toni Choueiri, MD, director of the Lank Center for Genitourinary Oncology at Dana - Farber.

Dr. Mohan specializes in the treatment of myelodysplastic syndromes and acute myeloid leukemia, with a focus on clinical trials and on translational research into secondary leukemias.

Initial tests will focus on clinical trials and real - world evidence data related to oncological data, according to the statements.

Not exact matches

The striking example I focused on then was the cancer drug Avastin, developed by Genentech (now Roche)-- which, at the time, had been studied in at least 400 completed human clinical trials for various cancers.

Shares of cancer - focused biotech Clovis Oncology soared nearly 50 % in early Monday trading on the strength of clinical trial results for its ovarian cancer treatment Rubraca.

Some small studies have suggested that synbiotics could provide benefits to a range of other conditions influenced by the gut microbiome as well, including obesity, diabetes, and non-alcoholic fatty liver disease, but larger - scale clinical trials focusing on each of those conditions are needed.

Investors, however, are focused on quarterly results and often have little patience with clinical trial setbacks and the years - long process of developing drugs.

After Abbott, he co-founded DCVC company BlueTalon, which was initially focused on enterprise data security for data - driven clinical trial design and population health management.

The future of research into the potential health benefits of cocoa should focus on the mechanisms and active compounds, with well defined clinical trials key to this burgeoning segment, says a new review by Nestlé.

With China expected to experience rapid growth in clinical trials over the short term, the Australian industry needs to remain competitive by focusing on quality factors as a differentiator.

The story aired last night, you can watch it here, and talked about something new and every thrilling — a clinical trial focused on coconut oil and Alzheimer's disease.

In addition to clinicians focusing on patient care, we have clinicians who also are educators and scholars as well as translational or clinical trial scientists.

The PhD course focuses on various aspects of human (donor) milk, with as main study a randomized clinical trial towards the effects of human donor milk in very low birth weight infants (the Early Nutrition Study).

«Unfortunately, most clinical trials to date have focused on patients whose cognitive deficits are already mild to severe, and when the therapeutic opportunities in this late stage of the disease are minimal.

«Current therapies in clinical trials are focused on targeting genetic changes in tumors and helping to boost one's immune system to fight the cancer cells.

Lanza says that this time, he aims to do things right: direct good science focused on treating disease, publish in reputable journals with rigorous peer - review processes and work with high - quality collaborators and clinical centres for its trials.

Clinical research focuses on interventional human trials to evaluate drugs and treatments in a controlled setting.

But philosophical assessment of such hierarchies has generally focused on randomized clinical trials.

Focus on courses that provide you with broadly applicable tools: information technology, informatics, drug development, clinical trials, medicinal chemistry, operations management, and regulatory affairs are obvious choices.

Previous research has largely focused on dietary components and which diet would be best to lower the risk of obesity and type 2 diabetes, but so far there is no clear evidence from epidemiological or clinical trial data that a specific diet is optimal for long - term weight - loss or lowering the risk of diabetes.

The German biotech CureVac, for example, has brought mRNA - based vaccines for rabies and cancer to clinical trials, and Karikó now heads a research team at BioNTech in Mainz, Germany, that focuses on mRNA - based drugs.

A health - agency windfall includes funding for two promising clinical trials, one focusing on prevention and the other on early treatment

POISE - 2 is the largest clinical trial focused on major cardiovascular complications in non-cardiac surgery.

In focus groups, he found that many patients still weren't entirely clear on the implications of certain financial arrangements after hours of discussion, and he worries that even simple statements might not be understood or taken into account properly when patients are deciding whether or not to participate in a clinical trial.

Bogyo and his associates focused on a compound called ebselen because, in addition to having a strong inhibitory effect, ebselen also has been tested in clinical trials for chemotherapy - related hearing loss and for stroke.

In addition to testing the overall efficacy of the solution, the 13 - week pilot clinical trial focused on the roles of psychological traits called locomotion (think of «just do it») and assessment («do it right»).

For example, if you and your fellow postdocs would like to learn about career opportunities in industry and biotech, you'll need to invite a variety of companies focusing on areas ranging from clinical trials to biotech start - ups to big pharma.

Working with the pharma and biotech industries, Poirier focuses on both performing the genetic tests in his laboratory and designing the clinical drug trials.

At a recent meeting, doctors, clinical trial experts, and statisticians made the case for a new type of experiment: pragmatic clinical trials, which focus less on basic biology and more on what doctors need to make decisions.

In 2011, he established the Immunotherapeutics Clinical Core, a specialized phase 1 outpatient unit at MSK that is focused on the conduct of novel immunotherapy trials, with a specific emphasis on pharmacodynamic biomarker identification.

Many clinical trials have since focused on trying to slow disease onset in these individuals.

The pharmaceutical industry, the National Institutes of Health, the FDA, academia, clinical research organizations and other key stakeholders will have the opportunity to focus on these disparities and identify the barriers and challenges in educating, recruiting and designing clinical trials.

The study is investigator led and has therefore focused on clinical need, targeting patients with progressive multiple sclerosis in whom most disability is incurred... The study also reports a predominant effect on neurodegenerative rather than inflammatory outcomes, suggesting a novel mechanism of action that might be suitable as combination treatment with immunomodulatory treatments... Further phase 3 studies to measure the effect of simvastatin on sustained disability, particularly in patients with non-relapsing secondary progressive and primary progressive multiple sclerosis, are clearly needed, but this trial represents a promising point from which to develop trials of progressive disease.»

Offsetting any such savings, according to CSDD, are higher costs due to the increased complexity of clinical trials, a greater focus on chronic and degenerative diseases, and tests for insurers seeking comparative drug effectiveness data.

The patients were enrolled in clinical trials sponsored by St. Jude or the Children's Oncology Group, an international clinical trials group focused exclusively on pediatric cancer.

The study, a retrospective survival analysis, included 229 patients who participated in two randomized, controlled clinical trials focused on relief of constipation for patients receiving palliative care for various types of late - stage cancer and other terminal diseases.

Up until now, efforts in generating a vaccine against TB have been mainly focused on T cells (cells from the adaptive arm of our immune response with memory capacity), with very disappointing outcomes in both pre-clinical as well as clinical trials.

«Our data argue for developing new clinical trials focused specifically on using these T memory cells, in order to determine if it would indeed be better than current therapeutic options,» said Dr. Snyder.

The research team is now focusing on preparing the nanoparticle eye drops for clinical trials with the hope that this nanoparticle therapy could reach the shelves of drugstores within five years.

Currently, a genomic analysis clinical trial at the Cancer Institute is focused on those patients with rare or poor - prognosis cancers, including pediatric patients.

He imagines that the collaboration will focus on areas that industry is currently exiting owing to their high risk — for example Alzheimer's disease, for which many promising drugs have failed in clinical trials.

This review focuses on kinase inhibitors that are in the clinic or in clinical trials and for which structural information is available.

«The Translational Medicine group focuses on how to bring promising scientific discoveries into clinical trials.»

Additional limitations to the traditional approach include: costly failures to replicate positive results in larger trials; difficulty in determining the reasons for negative results; low yield in terms of identifying disease or intervention mechanisms due to an exclusive focus on symptom change and clinical endpoints; and, the expensive and very lengthy practice of first establishing multi-component psychosocial treatments followed by years of «unpacking» studies.

To date, researchers have focused clinical trials of Onyx - 015 on cancer types that previous studies have shown often have inactivated p53, though the drug has been administered randomly.

He led Daiichi Sankyo's international research unit focused on early oncology therapeutic programs, strategy and development, and was accountable for development activities from post-target identification basic science research to first - in - man trials and proof - of - clinical concept.

Before being recruited to the pharmaceutical industry, Dr. Matushansky was a Professor at the Columbia University Medical Center where he ran an independent laboratory and clinic focusing on the molecular biology, translational opportunities and clinical trials in sarcomas.

The GDC will support clinical trials that focus on single patients, known as «n of 1» clinical trials, and will become an important component in how precision medicine is used to treat individual patients.

Maren Monsen, Director of the Stanford Program in Bioethics in Film, will present a screening of her documentary film «Rare», which focuses on a rare genetic disorder, and discussion of the importance of patient advocacy groups and clinical trials process in the United States.

Our current efforts in the AST - VAC2 program are focused on progressing this product towards a Phase 1 / 2a clinical trial in non-small cell lung cancer in collaboration with Cancer Research UK (CRUK).