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Hidden in the tangled, repetitious
folds of DNA
structures called centromeres, researchers from Harvard Medical School and the Broad Institute have discovered the hiding place of 20 million
base pairs of genetic sequence, finding a home for 10 percent of the DNA that is thought to be missing from the standard reference map of the human genome.
b) A Monte - Carlo search algorithm
based on secondary
structure elements While the backbone geometry of a protein determines the overall
fold, it is extremely computationally expensive to search the conformational space using backbone angles.
Other reports that address fundamental questions in structural biology, such as
structure -
based examinations of protein evolution,
folding, and / or design, will also be considered.
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