Sentences with phrase «follicle stem»

The group observed that, at the cellular level, one of the side effects of the diet was an expansion of hair follicle stem cells, leading to increasing hair follicle growth and retention rates.

Using a nuclear protein expressed in follicle stem cells (FSCs), the researchers found that castor, which plays an important role in specifying which types of brain cells are produced during embryonic development, also helps maintain FSCs throughout the life of the animal.

What's more, they identified Cas as a critical, tissue - specific target of Hh signaling, which not only plays a key role in maintaining follicle stem cells but also assists in the diversification of their progeny.

The study also adds to a growing sense that immune cells play much broader roles in tissue biology than had previously been appreciated, said Rosenblum, who plans to explore whether Tregs in the skin also play a role in wound healing, since the same follicle stem cells are involved in regenerating skin following injury.

First, imaging experiments revealed that Tregs have a close relationship with the stem cells that reside within hair follicles and allow them to regenerate: the number of active Tregs clustering around follicle stem cells typically swells by three-fold as follicles enter the growth phase of their regular cycle of rest and regeneration.

The bulge is where the majority of the hair follicle stem cells reside, and these can give rise to multipotent progenitor cells.

They then showed that removing Tregs from the skin significantly reduced Notch signaling in follicle stem cells, and that replacing Tregs with microscopic beads covered in Jag1 protein restored Notch signaling in the stem cells and successfully activated follicle regeneration.

This role created interest in studying hair follicle stem cells to better understand androgenetic alopecia (AGA), or male pattern baldness, the most frequent type of hair loss among men.

Naturally, the hair follicle stem cells were the prime suspects for causing AGA.

Surprisingly, it was found that different progenitor cell populations, suspected to be derived from the hair follicle stem cells, were in fact the ones playing the key roles in causing AGA.

However, earlier this month a study by George Cotsarelis at the University of Pennsylvania School of Medicine and colleagues published in The Journal of Clinical Investigation (Garza et al., 2011) revealed that patients with AGA actually had had a normal amount of follicle stem cells in their scalps.

The bulge region is believed to be the storage area for hair follicle stem cells.

Vitamin A activates hair follicle stem cells, moisturizes hair strands and protects it from being fragile.