Sentences with phrase «follicular b»

C, follicular B - cell lymphoma in the spleen.

All of the lymphomas involved the B - cell lineage and were further classified in most cases as centroblastic - centrocytic or centroblastic follicular B - cell lymphomas (Fig. 2C) ⇓.

Not exact matches

Follicular helper T cells (Tfh cells, shown in blue) play a crucial role in the maturation of antibody - producing B cells (shown in green).

When in the light zone, B cells are selected by follicular helper T (TFH) cells for migration to the dark zone.

A form of non-Hodgkin lymphoma, follicular lymphoma develops when the body starts making abnormal B - cells, which are white blood cells that in normal conditions fight infections.

They did discover that the inhibition changes the ways cells move within lymph nodes and the spleen, organs in which T follicular helper cells interact with B cells to promote antibody production.

In a mouse model of type 1 diabetes, RGS1 affects the population of one type of T cell called a «T follicular helper cell» that is critical for B cells and antibody production, Dr. Kissler and his colleagues reported recently in Genes and Immunity.

«In a nutshell, what we found is that this gene has an effect on the frequency of these T follicular helper cells, which are important for the B cells and seem to be important for the disease,» says Dr. Kissler, who is also an assistant professor of medicine at Harvard Medical School.

«Overall, the T follicular helper cells are important for B cells, you have more of those T cells in people with type 1 diabetes, they seem to be very important for the disease, and we have a new explanation of why RGS1 has been implicated,» Dr. Kissler sums up.

Dose - densified chemoimmunotherapy followed by systemic central nervous system prophylaxis for younger high - risk diffuse large B - cell / follicular grade 3 lymphoma patients: results of a phase II Nordic Lymphoma Group study.

Exon - Based Transcriptome Profiling Reveals Genes That Have Prognostic Impact on the Survival of Young High Risk Diffuse Large B - Cell / Follicular Grade 3 Lymphoma Patients Treated with Dose - Dense Chemoimmuno - therapy and CNS Prophylaxis.

The FDA granted approval to rituximab and hyaluronidase (Rituxan Hycela) for patients with follicular lymphoma (FL), diffuse large B cell lymphoma (DLBCL), and chronic lymphocytic leukemia (CLL).

The HZI will develop a vaccination protocol for mucosal administration based on three novel strategies: (i) development and optimization of a vaccination protocol in which parenterally - primed T and B cells are subsequently pulled into the mucosa by the local delivery of the cognate antigen to the requested effector site, (ii) testing the co-administration of antigens with novel mucosal adjuvants using different mucosal immunisation routes and schedules, and (iii) testing various nanoparticles co-administered with different immunomodulators for their ability to generate both systemic and mucosal immune responses following transcutaneous / trans - follicular vaccination.

Censoring of Self - Reactive B Cells by Follicular Dendritic Cell — Displayed Self - Antigen.

Follicular lymphoma is a type of B - cell lymphoma and a form of non-Hodgkin lymphoma, that is slow growing and indolent.

Notch ligands expressed by follicular dendritic cells protect germinal center B cells from apoptosis.

CD9 may contribute to the survival of human germinal center B cells by facilitating the interaction with follicular dendritic cells.

Aborted germinal center reactions and B cell memory by follicular T cells specific for a B cell receptor V region peptide.

Follicular dendritic cells produce IL - 15 that enhances germinal center B cell proliferation in membrane - bound form.

His group defined a functional niche for B cells (around sinusoids in the bone marrow), identified the first two mutants that abrogate marginal zone B lymphocyte development, developed the concept of a follicular versus marginal zone B lymphoid cell - fate decision, and discovered two new defined stages of peripheral B cell development, the marginal zone precursor (MZP) B cell, and the Follicular type follicular versus marginal zone B lymphoid cell - fate decision, and discovered two new defined stages of peripheral B cell development, the marginal zone precursor (MZP) B cell, and the Follicular type Follicular type II B cell.

Altered Memory Circulating T Follicular Helper - B cell Interaction in Early Acute HIV Infection.

These patients had either chemorefractory DLBCL or variants of DLBCL like primary mediastinal B - cell lymphoma or transformed follicular lymphoma.