Sentences with phrase «following bone marrow»

Hyperimmune bovine colostrum has been used in clinical trials for treating AIDS - related diarrhea, diarrhea associated with graft versus host disease following bone marrow transplant, and rotavirus diarrhea in children.
Importantly, the team also found that, in mice, antibody - mediated stimulation of this receptor following a bone marrow transplant increased the number of donor - derived T - cells and boosted initial thymus recovery.
Now, in a study recently published in the journal PLOS ONE, a team of scientists from VCU Massey Cancer Center have shown a genetic relationship between the reactivation of hCMV and the onset of graft - versus - host disease (GVHD), a potentially deadly condition in which the immune system attacks healthy tissue following a bone marrow or stem cell transplant.
These cells spring into action following bone marrow transplants, bone marrow injury and during systemic infection, creating new blood cells, including immune cells, in a process known as hematopoiesis.
There is one previous case of an HIV - positive individual seemingly being cured following a bone marrow transplant, but the donor was HIV - resistant.
«Proper blood cell production is dependent on functioning hematopoietic stem and progenitor cells that are destroyed during conditioning procedures for transplantation or following bone marrow injury,» said the study's first author Kevin A. Goncalves, who performed this research as part of his PhD studies in cellular and molecular physiology at the Sackler School.

Not exact matches

It begins with bone marrow on toast, then follows with broth and the meats and vegetables.
The work was on the role of interleukin - 1 in the pathology of graft - versus - host disease (GVHD), the mechanism by which the new immune system, which a patient receives as a bone marrow transplant, attacks the patient's body following the transplantation.
«Long - term follow - up of at least one year will be required to understand the full impact of a bone - marrow transplant on HIV persistence.»
Two men known only as the «Boston patients» have both stopped taking their anti-HIV medications following transplants of bone - marrow stem cells that appear to have banished the virus from their bodies.
In further studies, the researchers tested the capacity of ANG to prevent and mitigate radiation - induced bone marrow failure, and in pre-clinical models, they found that survival following radiation exposure was increased after treatment with recombinant ANG protein.
Eight of nine patients who are evaluable for response had no evidence of disease in their bone marrow at three months, and all remain in remission after a median follow - up period of six months, with a range from 0.5 to 9 months.
The researchers used a new cell tracing method to follow the movement of peritubular macrophages from the bone marrow to the testes.
Using an approach developed at Maisonneuve - Rosemont, consisting of an autograft to reduce tumour mass followed by a family allograft three to four months later to clean the bone marrow of myeloma cells with immune cells from a family donor (immunotherapy), the study resulted in a total cure rate of 41 %, a record level using this strategy.
In the phase I / II clinical trial of 20 patients, the engineered cells were deemed safe, trafficked to the site of the tumor (bone marrow), and persisted in 90 percent of the patients who reached two years follow up after infusion, the research team found.
The researchers, led by Professor Sten Eirik W Jacobsen at the MRC Molecular Haematology Unit and the Weatherall Institute for Molecular Medicine at the University of Oxford, investigated malignant cells in the bone marrow of patients with myelodysplastic syndrome (MDS) and followed them over time.
Both scientists and their labs had discovered that Del - 1 was also expressed in the bone marrow and began following up to see what its function was there.
Rodriguez also concludes that including selective facial bone structure in addition to the chin of the donor provided natural bone marrow stem cells to help the transplanted face thrive following the surgery, and provided the necessary positional support for the facial soft tissues.
«Until now, physicians have taken a «wait and see» approach to antiviral therapies following transplantation,» says Toor, a hematologist - oncologist in the Bone Marrow Transplant Program and member of the Developmental Therapeutics research program at VCU Massey Cancer Center as well as professor in the Division of Hematology, Oncology and Palliative Care at the VCU School of Medicine.
This technology has been developed from a skin explant model for predicting a potentially serious complication of bone marrow transplantation, «graft versus host» disease — a common complication following the transplant.
It is composed of two elements: treating the patient with antibodies on the day of transplant, followed by a donor bone marrow infusion several days later.
An example of this type of circuitry analysis includes measuring and interpreting all of these parameters over a time course, following stimulation of mouse bone marrow - derived dendritic cells with bacterial lipopolysaccharides (LPS) endotoxin.
Dr. Goodman is also involved in collaborative efforts with the San Antonio Bone Marrow Transplant Center to study the outcome of allogeneic bone marrow transplants following a relapse from autologous bone marrow transplaBone Marrow Transplant Center to study the outcome of allogeneic bone marrow transplants following a relapse from autologous bone marrow transpMarrow Transplant Center to study the outcome of allogeneic bone marrow transplants following a relapse from autologous bone marrow transplabone marrow transplants following a relapse from autologous bone marrow transpmarrow transplants following a relapse from autologous bone marrow transplabone marrow transpmarrow transplants.
Dr. Maharaj obtained his medical degree from the University of Glasgow Medical School, Scotland and completed his internship and residency in Internal Medicine and Hematology followed by specialist fellowship training in Hematology, Oncology and Bone Marrow Stem Cell Transplantation at the University's Glasgow Royal Infirmary, Scotland.
As Dr. Maharaj explained, «One last option for Gale was high dose chemotherapy followed by an autologous bone marrow stem cell transplant.
Bone marrow - derived mesenchymal stem cells (BM - MSCs) are obtained by isolating mononucleated cells from a marrow aspirate by centrifugation on a density gradient, followed by adherent cell expansion in tissue culture.
Residual leukemic cells that remain in the bone marrow following treatment are a major cause of disease relapse and can also act as an early indicator to the effectiveness of a given treatment strategy.
Patients who receive HSCT receive high doses of chemotherapy, with or without radiation, followed by infusion of hematopoietic stem cells (HSCs)-- rare cells that reside within the bone marrow and are capable of producing all varieties of blood cells.
CBC (complete blood count) / differential obtained within 14 days prior, with adequate bone marrow function defined as follows:
Goyal RK, Lin Y, Schultz KR, Ferrell RE, Kim Y, Fairfull L, Livote E, Yanik G, Atlas M. Tumor necrosis factor - alpha gene polymorphisms are associated with severity of acute graft - versus - host disease following matched unrelated donor bone marrow transplantation in children: a Pediatric Blood and Marrow Transplant Consortium marrow transplantation in children: a Pediatric Blood and Marrow Transplant Consortium Marrow Transplant Consortium study.
Malignant cells that remain in the bone marrow following treatment are a major cause of disease relapse.
They found that Lymphotoxin β receptor, a cell surface molecule, controls the entry of T - cell progenitors to the thymus, both in a healthy state and during immune recovery following bone - marrow transplantation.
On learning that she landed an interview with Barack Obama (that would occur the following day) on the day she endured a painful bone marrow extraction for the blood condition myelodysplastic syndrome: «[It] reminds me that God only gives us what we can handle and that it helps to have a good sense of humor when we run smack into the absurdity of life.»
Research reveals that individuals with type 2 diabetes who received self - donated bone marrow stem cell transplants needed less insulin following the transplants, in comparison to a control group of individuals with type 2 diabetes who didn't receive transplants.
Many of us who seek to follow the nutritional wisdom of our ancestors make bone broth, very often with marrow bones included.
In the wild, animals go for the liver and the bone marrow first, followed by the heart, kidneys, pancreas and spleen.
A more recent treatment option has been to administer a bone marrow transplant following successful chemo, in hopes that new white blood cells produced by the donated marrow will be able to find and kill the cancerous blood cells circulating in the patient's body, he said.
Within two days following infection, the virus spreads to lymph nodes and tonsils, and then throughout the body to bone marrow, spleen, and other lymph nodes.
Following replication, it infects the rest of the lymphatic system and bone marrow, where it continues to replicate repeatedly for several days.
The critical illnesses covered under the Standard Plan are as follows — cancer of a specified severity, stroke resulting in permanent symptoms, first heart attack of specified severity, open chest CABG, kidney failure requiring regular dialysis, Multiple Sclerosis with persisting symptoms, major organ / bone marrow transplant, permanent paralysis of limbs, surgery of aorta, primary pulmonary arterial hypertension.
During 9 years of follow up, 157 blood, bone marrow, and lymph system cancers developed in the study group.
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