Collection of such material was approved by the ethical committee of the National Center
for Cell Science, Pune and signed written consent was obtained from adult patients (50 to 70 years old) who underwent cardiac bypass surgery.
Funding: This research was supported by the Intramural Research Program of the National Center
for Cell Science, Department of Biotechnology, Government of India (NCCS / DBT / INTRA -26 / 2005 - O) to AAH.
The Institute is a recognized leader in large - scale research with a commitment to an open science model within its research institutes, the Allen Institute for Brain Science, and the Allen Institute
for Cell Science.
Mouse melanoma cell line B16F10 was procured from National Centre
for Cell Science, Pune, India as well as from Department of Radiation Biology and Toxicology, School of Life Sciences, Manipal, India.
«Techniques like this tend to have a democratizing effect,» opening up opportunities for smaller groups, Molly Maleckar, the director of mathematical modeling at the Allen Institute
for Cell Science who was not involved in the study, tells Wired.
Now, new research from the laboratory of Vaijayanti P. Kale (National Centre
for Cell Science, Pune, Maharashtra, India) has described a fascinating new approach to return lost functionality to aged mouse HSCs: the transfer of microvesicles (MVs) containing positive regulators of autophagy derived from young mesenchymal stem cells (MSCs)[6].
Not exact matches
«Things that would have seemed
science fiction to me just maybe five to 10 years ago — like getting a billion
cells for each heart — now are doable,» LaFlamme, the investigator on the heart program, said.
February 2, 2017 By Ann Perry http://mbd.utoronto.ca/ When Arif Aziz learned last fall about a new independent study project that was bringing together MBA candidates and PhD students in health
sciences and engineering to map the global market
for stem
cell therapies, he jumped at the opportunity.
But rather than incentivize teaching innovation that would allow
science educators to discuss religion and ethics ---
for example, creationism in light of evolution and vice versa, or the scientific and ethical implications of stem
cells and in vitro fertilization — many teachers are afraid to even mention these issues, despite their importance,
for fear of losing their jobs.
A 17 - year - old California girl won $ 100,000 in a national
science competition
for her creation of a nanoparticle that can target and kill cancer
cells.
The ANT - OAR proposal represent a scientifically and morally sound means of obtaining human pluripotent stem
cells that does not compromise either the
science or the deeply held moral convictions of those who oppose the destructive use of human embryos
for research» which is a creative approach that can be embraced by both the anything - goes camp and the nothing - goes.
One clear positive element in the stem -
cell debate
for me was hearing the top researchers in biomedical
science reinforce The Catechism of the Catholic Church (CCC 343: «Man is the summit of the Creator's work, as the inspired account expresses by clearly distinguishing the creation of man from that of other creatures»).
The kind of
science that makes the claim
for evolution is NOT the same
science that gives us the great quality of life that most of us have everyday (medicine, cars, electricity, airplanes,
cell phones, etc).
So, the
cell needs the energy that the mitochondria creates (ATP
for those not reading their
science books)?
Fairies and gods, if they exist, occupy something of the same conceptual space as organic
cells, photons, and the force of gravity, and so the
sciences might perhaps have something to say about them, if a proper medium
for investigating them could be found.
While President Bush stood firm, the issue of stem
cell research appeared to be a political winner
for Democrats and to pit the claims of
science against strict ethical guidelines.
He has more than fifteen years» experience in the life
science industry, including the product development, market development and commercialization of
cells, scaffolds,
cell reprogramming tools and
cell culture media
for regenerative medicine and bioprocessing applications.
Jiachen Lee, Arooba Ahmed and Jillian Parker, a trio of young scientists from the Half Hollow Hills school district won the $ 100,000 top team award in the prestigious Siemens Competition in Math,
Science & Technology
for their research into
cell division that could help find treatments to cancers, viruses and other diseases.
«American Association
for the Advancement of
Science (AAAS) Statement Regarding the President's Veto of the Stem
Cell Research Enhancement Act and the New Executive Order» [20 June 2007]
Judging the entries were Bob Goldman of Northwestern University's Feinberg School of Medicine, Robert Krulwich,
science correspondent
for National Public Radio, Dave Mosher,
science and technology correspondent
for Business Insider, and Clare Waterman, of the Laboratory of
Cell and Tissue Morphodynamics at the National Institute of Health.
Funding
for this research came, in part, from the National Institutes of Health (1R01NS091010 - 01, 1R01DC014690 - 01), Japan
Science and Technology Agency (PRESTO), Pew Charitable Trusts, Alfred P. Sloan Foundation, David & Lucile Packard Foundation, Human Frontier
Science Program, McKnight Foundation and New York Stem
Cell Foundation.
Researchers at the Center
for Engineering MechanoBiology (CEMB), an NSF
Science and Technology Center at the University of Pennsylvania, study plants like this Arabidopsis thaliana to learn how molecules,
cells and tissues integrate mechanics within plant and animal biology, with the aim of creating new materials, biomedical therapies and agricultural technologies.
«Once this novel tumor - homing agent binds to the EphA2 receptor, the oncogene functions as a cancer - specific molecular Trojan horse
for paclitaxel, carrying the drug inside the cancel
cell, killing the
cell, and thwarting metastasis,» said Maurizio Pellecchia, a professor of biomedical
sciences at UCR's School of Medicine who led the research.
Toxicologist Thomas Hartung described these minibrains, grown from stem
cells derived from people's skin
cells, at the annual meeting of the American Association
for the Advancement of
Science.
The winner of the Sartorius &
Science Prize
for Regenerative Medicine &
Cell Therapy is awarded US$ 25,000 and publication of his or her essay in
Science.
The design and formation of an atomic - scale bridge between different materials will lead to new and improved physical properties, opening the path to new information technology and energy
science applications amongst a myriad of
science and engineering possibilities —
for example, atoms could move faster at the interface between the materials, enabling better batteries and fuel
cells.
The new technology, described in the journal Molecular
Cell, offers a new way to seek drug targets
for many diseases, not just Parkinson's, says Timothy Lu, an MIT associate professor of electrical engineering and computer
science and of biological engineering.
The year's most prominent
science issue, federal support of embryonic stem
cell research, is so controversial that the sons of Ronald Reagan gave dueling speeches at the opposing party conventions; Michael Reagan backs President George W. Bush's policies, including the ban on funding
for research on new stem
cell lines, while Ron supports Senator John Kerry's promise to lift restrictions.
My research has implemented MFC methods
for cell manipulation and molecular biology and has been applying them in collaboration with local life
science researchers.
Figuring out how blank slate stem
cells decide which kind of
cell they want to be when they grow up — a muscle
cell, a bone
cell, a neuron — has been no small task
for science.
The researchers are building on their current findings, which they say establishes a system
for reconstituting
cell fusion in mammalian
cells, a feat not yet achieved by biomedical
science.
Yes, but the difference is that there are pretty obviously enormous opportunities
for doing good
science with stem
cells.
Core Research
for Evolutional
Science and Technology and Yamanaka iPS
Cell Project, Japan
Science and Technology Agency, Kawaguchi 332-0012, Japan.
Some were associated with haemoglobin and red blood
cell production,
for example (
Science, vol 329, p 75).
Contacted by
Science about the e-mail, one of the corresponding authors, Thomas Perlmann of the Karolinska Institute in Stockholm, responded that the images are from triple immunohistochemistry staining, so are indeed from the same set of
cells «displayed as double staining
for clarity.»
Dr Florent Ginhoux, Dr Andreas Schlitzer and colleagues from the Singapore Immunology Network (SIgN), a research institute under the Agency
for Science, Technology and Research (A * STAR) in Singapore, together with Dr Shalin Naik and Mr Jaring Schreuder from Melbourne's Walter and Eliza Hall Institute, discovered each subtype of dendritic
cell had its own, unique parent
cell.
So far, researchers with the Allen Institute
for Brain
Science in Seattle have described the intricate shapes and electrical properties of about 100 nerve
cells, or neurons, taken from the brains of 36 patients as they underwent surgery
for conditions such as brain tumors or epilepsy.
«The placement of the pegs that this group of
cells wraps itself around and then exerts force on each other is what dictates their alignment and the direction of the ECM they are going to synthesize,» said senior author Jeffrey Morgan, professor of medical
science and engineering and co-director of Brown's Center
for Biomedical Engineering.
The only way the team can be sure they have grown the equivalent of a fetal brain would be to genetically test individual
cells from different regions of the organoid, and compare them to those of human fetus, says Christof Koch at the Allen Institute
for Brain
Science in Seattle.
«To treat most forms of hearing loss, we need to find a delivery mechanism that works
for all types of hair
cells,» said neurobiologist David Corey, co-senior investigator on the study and the Bertarelli Professor of Translational Medical
Science at HMS.
This collaboration reflects work of The Center
for Engineering Mechanobiology, a National
Science Foundation - funded
Science and Technology Center that supports interdisciplinary research on the way
cells exert and are influenced by the physical forces in their environment.
Douay,
for his part, is not surprised it has taken more than a century
for science to get even to this point, where the future of subbing in stem
cells for blood products still remains little more than a reverie.
The elevation in a growing embryo's temperature, called hyperthermia, impacts the activity of heat - sensitive channels that are present in
cells necessary
for an embryo's development, researchers report online October 10 in
Science Signaling.
In
science news around the world, scientists march in India to call
for more research funding, a South Korean researcher who was enmeshed in a stem
cell scandal a decade ago resigns from a newly created government position, Canada establishes a vast marine conservation area in the High Arctic, a highly regarded advocate
for science is convicted of financial misdemeanors in Egypt, and more.
In a recent issue of Trends in Plant
Science, František Baluška, a plant
cell biologist at the University of Bonn in Germany, and Stefano Mancuso, a plant physiologist at the University of Florence in Italy, lay out new evidence
for visually aware vegetation.
Renowned
for his extensive work in molecular genetics, Brenner is best known locally
for his role in bringing leading - edge biomedical
sciences research to Singapore and in spearheading the Fugu genome project, which brought the Institute of Molecular and
Cell Biology international recognition.
In an article that appears in the online edition of
Science, UMMS Professor Job Dekker, PhD, and colleagues show new evidence
for a general principal of condensed, mitotic chromosome organization and structure that is highly adaptable and common to all
cells.
«I don't really think growing
cells in space
for clinical use on Earth is
science fiction,» he says.
In
science news around the world, the U.S. Food and Drug Administration (FDA) cracks down on stem
cell labs, Brazil opens one of its largest national reserves to gold and iron mining, and the International Atomic Energy Agency launches a global bank
for low - enriched uranium.
A group of scientists at Okinawa Institute of
Science and Technology Graduate University (OIST) and collaborators at Stockholm University showed
for the first time how this big protein complex inside living E. coli
cells disassembles after each round of division.