Sentences with phrase «for tuberculosis drug»
La Montagne chaired the World Health Organization Task Force on Strategic Planning for the Children's Vaccine Initiative, advised the Pan American Health Organization on programs for vaccine - research implementation, and served as a member of the board for the Global Alliance for Tuberculosis Drug Development.
http://www.sciencemag.org/ Not exact matches
Cycloserine, a drug used to treat dangerous multidrug - resistant tuberculosis, was just increased in price to $ 10,800 for 30 pills from $ 500 after its acquisition by Rodelis Therapeutics.
These include the infant with galactosemia, 53,54 the infant whose mother uses illegal drugs, 55 the infant whose mother has untreated active tuberculosis, and the infant in the United States whose mother has been infected with the human immunodeficiency virus.56, 57 In countries with populations at increased risk for other infectious diseases and nutritional deficiencies resulting in infant death, the mortality risks associated with not breastfeeding may outweigh the possible risks of acquiring human immunodeficiency virus infection.58 Although most prescribed and over-the-counter medications are safe for the breastfed infant, there are a few medications that mothers may need to take that may make it necessary to interrupt breastfeeding temporarily.
The Russian government has recently implemented more rigorous health requirements for adopting parents — a history of psychiatric disorders, drug and alcohol addictions, tuberculosis, and infectious diseases, for example, may disqualify potential parents.
Breastfeeding is also not recommended for women who have a health issue such as HIV or tuberculosis, those who use illegal drugs, or women who have to take certain prescription medications that are not compatible with breastfeeding.
Breastfeeding is contraindicated in infants with classic galactosemia (galactose 1 - phosphate uridyltransferase deficiency) 103; mothers who have active untreated tuberculosis disease or are human T - cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a small number of other medications until they clear the milk109, 110; mothers who are using drugs of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from other breast if clear of lesions).
So are drugs for tuberculosis, leprosy, epilepsy or for psychiatric illness.
«For example, some cancers may not impact many patients and some antibacterial drugs, such as that for drug - resistant tuberculosis, may not be profitable, but it is almost a responsibility of biomedical researchers in academics to do something about it.&raqFor example, some cancers may not impact many patients and some antibacterial drugs, such as that for drug - resistant tuberculosis, may not be profitable, but it is almost a responsibility of biomedical researchers in academics to do something about it.&raqfor drug - resistant tuberculosis, may not be profitable, but it is almost a responsibility of biomedical researchers in academics to do something about it.»
Using the second drug with bedaquiline made tuberculosis bacteria more vulnerable, pointing to a potential strategy for dealing with persistent infections.
The drug turns off some of the regulators for the overactive tuberculosis gene network that was fighting off the bedaquiline.
New research conducted at the Center for Tuberculosis Research at the Johns Hopkins University School of Medicine shows that lower doses of the toxic drug bedaquiline — given together with verapamil, a medication that's used to treat various heart conditions — can lead to the same antibacterial effects as higher toxic doses of bedaquiline.
The team analysed drug sales data to show that the actual number of tuberculosis cases in India may be vastly under - reported, primarily because many people opt for treatment from private healthcare providers, who usually fail to report tuberculosis cases to public health officials.
The standard treatment regimen for drug - sensitive tuberculosis comprises four different drugs.
Current drug therapies for drug - sensitive tuberculosis require six to eight months of treatment; for drug - resistant tuberculosis, treatment can take as long as two years.
Frieden said the halt has raised concerns from researchers working on drug - resistant tuberculosis, the Ebola outbreak in Africa, and preparations for next season's influenza vaccine.
Nearly 40 % of all drug - resistant tuberculosis cases occur in Russia, India, the Philippines, and South Africa — accounting for more than 230000 cases of drug - resistant disease in 2015.
«The discovery of an alternative binding site and the AAPs represents a significant step towards the identification of a novel RNAP inhibitor that would behave like rifampin but be devoid of any pre-existing resistance,» said Nader Fotouhi, Chief Scientific Officer at the Global Alliance for TB Drug Development, a not - for - profit organization dedicated to finding faster - acting and affordable drug regimens to fight drug sensitive and resistant tuberculoDrug Development, a not - for - profit organization dedicated to finding faster - acting and affordable drug regimens to fight drug sensitive and resistant tuberculodrug regimens to fight drug sensitive and resistant tuberculodrug sensitive and resistant tuberculosis.
«Tuberculosis (TB) remains a major global health problem and identifying new drug targets and candidate drugs is a major priority,» said David S. Perlin, Executive Director and Professor at the Public Health Research Institute and Rutgers Regional Biocontainment Laboratory at the International Center for Public Health at Rutgers New Jersey Medical School in Newark.
There are two forms of drug - resistant tuberculosis important to public health — multidrug - resistant tuberculosis is resistant to more than one of the first - line drugs for the disease, whereas extensively drug - resistant tuberculosis is additionally resistant to fluoroquinolones and at least one of the second - line injectable tuberculosis drugs.
The study authors propose that increased spread from person to person will be responsible for the growing number of drug - resistant tuberculosis cases.
Backup plan Sven Hoffner, a clinical mycobacteriologist at the Swedish Institute for Communicable Disease Control in Solna, says that drug - resistant tuberculosis is «a manmade problem», often because drugs are not available or of poor quality.
The study followed 1,055 household contacts of 213 individuals with MDRTB infection (defined by resistance to the drugs rifampicin and isoniazid), and 2,362 household contacts of 487 individuals with drug - susceptible tuberculosis for up to three years.
Previous laboratory findings as well as estimates of fitness based on genetic clustering of strains in the population suggested a lower relative fitness for MDRTB compared to drug - susceptible tuberculosis, but few studies have directly measured the incidence of second cases of tuberculosis among contacts of both MDRTB and drug - susceptible tuberculosis.
«We hope to refine these multivariable descriptions so that we can anticipate the cyclic changes to drug susceptibility in mycobacteria, and eventually use them to shorten the long and difficult treatment course for tuberculosis.»
Johns Hopkins researchers have developed a computer simulation that helps predict under which circumstances a new short - course treatment regimen for drug - resistant tuberculosis could substantially reduce the global incidence and spread of the disease.
And unlike for most other drug - resistant pathogens, we have evidence that, with a comprehensive response, drug - resistant tuberculosis epidemics can be rapidly reversed.
«Promising class of antibiotics discovered for treatment of drug - resistant tuberculosis.»
6 - dependent protein, potentially opening avenues for new antibiotics and drugs to battle diseases such as drug - resistant tuberculosis, malaria and diabetes.
The so - called «international» edition of HIV / AIDS Medicine features up - to - date clinical information on HIV / AIDS, such as the best treatment options for patients with drug - resistant tuberculosis — a condition often found among HIV - positive individuals — but also includes specialized chapters on managing and treating HIV and AIDS in resource - poor settings.
WHO guidelines for the programmatic management of drug - resistant tuberculosis: 2011 update.
Researchers at University of California, San Diego School of Medicine have documented the accuracy of three new tests for more rapidly diagnosing drug - resistant forms of tuberculosis (TB), which are much harder and more expensive to treat and which, experts say, represent a major threat to global public health.
Aaron's work involves the management of projects and assays involved in drug discovery for tuberculosis.
The project that is farthest along involves the discovery of small molecules for use in combination with drugs of last resort for extensively drug - resistant tuberculosis infections.
Higher frequency of genetic variants conferring increased risk for ADRs for commonly used drugs treating cancer, AIDS and tuberculosis in persons of African descent.
As with other biologics, patients should undergo testing for tuberculosis before starting Stelara, and while taking the drug they should be tested for TB once a year.
«It's the case in measles, it's the case for drug - resistant tuberculosis, it's the case for MERS and SARS and Ebola.
Garlic has even been suggested as a treatment for drug - resistant tuberculosis.
Mycobacterium tuberculosis (Mtb) DprE1, an essential isomerase for the biosynthesis of the mycobacterial cell wall, is a validated target for tuberculosis (TB) drug development.
Stacy Byers, PhD, Washington State University «Reducing the Risk of Transmission of Pathogenic Bacteria to Bighorn Sheep» Mary Klinck, DVM, University of Montreal «Creating Validated Pain Scales for Feline Osteoarthritis Pain Identification and Quantification» Alex Davies, PhD University of California — Davis «Understanding Mechanisms that Contribute to Early Changes in Cancer Stem Cells» Kristen Messenger, DVM, North Carolina State University «Analgesic Drug Therapy in Animals» Tiffany Wolf, DVM, University of Minnesota «Identification of Factors Contributing to Mycobacterium Tuberculosis Transfer between Humans and Great Apes»
The solutions examined were: fighting tuberculosis through drugs and improved case identification; getting cheap drugs that treat acute heart disease to developing countries; combining a malaria prevention package (mosquito nets, DDT spray, etc.) with subsidies on new treatments; expanding immunization and micronutrient coverage for children in developing nations; tobacco taxes in developing nations; and a multiple ‐ intervention approach to preventing and treating H.I.V. / AIDS; making investments in hospitals.