«It is satisfying to find that a fundamental observation regarding the genetics and biochemistry of the pathogen can have implications not only for strep disease pathogenesis, but
also for vaccine design,» Nizet said.
«These new findings are consistent and complementary with previous work by IAVI and partners and together could offer a possible
template for vaccine design,» said Landais.
William Schief is a Professor in the Immunology and Microbial Science Department at The Scripps Research Institute in La Jolla, CA,
Director for Vaccine Design at the International AIDS Vaccine Initiative (IAVI), and an Associate Member of the Ragon Institute of MGH, MIT and Harvard.
Working with a world - leading group at the University of Connecticut in the USA, who pioneered the development of self - assembling protein nanoparticles (SAPNs)
for vaccine design, they have used advanced mathematical calculations to create a complete picture of the surface morphology of these particles.