Sentences with phrase «for additional diseases»

Newborn screening programs vary by state, but most include the disorders recommended by the HHS, and many states test for additional diseases.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

Last weekend, Scott sharply criticized the federal government and lawmakers for dragging their feet in providing resources needed to combat the disease, including 10,000 Zika preparedness kits, mosquito spray and additional manpower to root out the mosquitoes.

The Xarelto partnership is seeking additional approved uses, with trials underway in patients with acute coronary syndrome, and for reduction of major adverse cardiovascular events in patients with heart failure or peripheral artery disease.

The drug is also being evaluated for treating two additional rare diseases.

Amicus Therapeutics, Inc. (NASDAQ: FOLD) announced the path forward for U.S. regulatory approval for migalastat, including an additional trial in Fabry disease, focused on gastrointestinal (GI) symptoms.

After completing this training if you are interested in further information regarding concussions, visit the additional resources link to find handy printouts, related articles and supplementary concussion websites such as STOP Sports Injuries and the Centers for Disease Control and Prevention's Head's Up: Concussion in Youth Sports.

Now, when you re-feed your baby that bottle (following Center for Disease Control guidelines, of course), you are decreasing the amount of additional bacteria your baby is exposed to.

After completing this training if you are interested in further information regarding abuse protection, visit the additional resources link to find handy printouts, related articles and access to supplementary abuse websites such as the National Center for Missing & Exploited Kids, Child Help, Centers for Disease Control: Child Maltreatment Prevention and Darkness to Light.

In fact, the celiac positive kids were breastfed on average for 1.4 additional months compared to those negative for the disease.

Poloncarz has proposed spending $ 3.75 million over five years to hire six additional health sanitarians and a nurse to manage the cases of children who test at levels that the Centers for Disease Control and Prevention considers to be concerning.

The Senate minority leader appeared Wednesday on Long Island and in Rockland County to urge the Centers for Disease Control to unlock millions in additional funding included in the recently passed federal budget.

It is funded by grants from the New York State Department of Health, Bureau of Chronic Disease Control, the Center for Disease Control and Prevention (CDC) with additional support from the Western New York affiliate of Susan G. Komen.

Predation accounted for 70 percent of the deaths, disease an additional 16 percent, and poisoning, which until lately hadn't been considered, 10 percent.

Jaenisch says that the method that identified the single point mutation in SNCA's enhancer could be used to pinpoint additional pathogenic genes for sporadic PD and sift through the GWAS hits for other diseases, including Alzheimer's disease, cancer, diabetes, and multiple sclerosis.

There was also less than one additional case for every 1,000 women per year for heart disease and for stroke in the hormone - treated women compared with those on placebo.

For example, in the combined hormone therapy trial, treated 50 - to 59 - year - olds had five additional cases of heart disease and five more strokes per 10,000 women annually compared with the same - aged group on placebo.

They said the key messages from the study were that stroke is a highly preventable disease globally, regardless of age and sex; that the relative importance of modifiable risk factors means there should be development of regional or ethnic - specific primary prevention programs, and that additional research on stroke risk factors is needed for countries and ethnic groups not included in INTERSTROKE.

To compute how additional pollution from ships increases risk of disease for exposed populations, especially those living in coastal communities or along major shipping lanes and far inland in some nations like India, the team incorporated important underlying health information from the World Health Organization and Global Asthma Network.

Existing customers can opt to receive BRCA information for no additional cost, and as with the other disease - risk tests they as well as new customers must specifically choose to receive the information.

A study by investigators at Brigham and Women's Hospital (BWH) published this week in PLOS ONE identifies four factors that may account for sex differences in statin therapy among patients with coronary artery disease (CAD), pointing to interventions and additional research that will be needed to help overcome this sex disparity and reduce cardiovascular risk for women.

Because environmental exposures have not had time to impact IBD progression in children, researchers have a clearer genetic picture of the disease allowing them to pick out additional genes overlooked in adult research, says senior study author Hakon Hakonarson, director of the Center for Applied Genomics at The Children's Hospital of Philadelphia.

This work was supported by grants from the National Institutes of Health (R01AA020331 and R01AA016187), the Centers for Disease Control and Prevention (U49CE001093), and the Robert Wood Johnson Foundation Health and Society Education Fund, with additional funding from the U.S. Department of Agriculture Forest Service.

Since smoking and obesity are risk factors for cardiovascular and metabolic diseases, the additional burden of craving more fats and sugars, while not fully tasting them, could be detrimental to health.»

By providing a framework based on unbiased quantitative analytics and big data, they hope to identify diseases that are high - impact and rewarding targets for additional investment.

Supported by pilot program funding from the UK Center for Clinical and Translational Science (CCTS), van Horne, with his team, is exploring an additional treatment option, and possibly a way to alter the course of the disease.

«We introduce a new definition of global health financing — one that includes additional public R&D spending for neglected diseases,» said lead author Marco Schäferhoff, PhD, of SEEK Development in Berlin, Germany.

The number of missing teeth could be a useful additional indicator for general medical practitioners, when individual risk factors for chronic diseases are assessed, researcher John Liljestrand states.

If additional work supports the finding, the study may provide researchers with potential new drug targets for the disease.

Since the long - term health effects experienced by children following severe disease likely differs from that of adults, researchers said that additional studies are needed to determine the health needs for children who survive EVD.

These additional genetic elements, however, are already in use for screening and testing for diseases such as breast cancer, prostate cancer and autoimmune diseases, Richard Myers, president of HudsonAlpha Institute for Biotechnology in Ala., noted in the briefing.

The authors will follow up the study with additional worldwide populations to better understand the mutations and these genes as a genetic marker for disease risk.

As those assays have matured, the scientists have begun to optimize additional tests for a number of emerging diseases.

Interestingly, IBS biologists uncovered additional miRNA end modifications after DROSHA processing, which are expected to be important for the regulation of miRNA biogenesis, whose dysregulation is often associated with diseases, in particular with cancer.

Data collected during a long - term health study provides additional evidence for a link between increased risk of cancer in individuals with advanced gum disease, according to a new collaborative study led by epidemiologists Dominique Michaud at Tufts University School of Medicine and Elizabeth Platz of the Johns Hopkins Bloomberg School of Public Health and Kimmel Cancer Center.

Professor Peymané Adab, Professor of Chronic Disease Epidemiology & Public Health, said: «This study contributes to existing evidence for sleep duration as a risk factor for obesity in childhood, and later bedtime as an additional risk factor — regardless of sleep duration.

Additional work recently presented at the 2014 American Society for Radiation Oncology in San Francisco carried the work further in order to determine whether protection from the additional radiation dose in fact translated to a reduction in ischemic hearAdditional work recently presented at the 2014 American Society for Radiation Oncology in San Francisco carried the work further in order to determine whether protection from the additional radiation dose in fact translated to a reduction in ischemic hearadditional radiation dose in fact translated to a reduction in ischemic heart disease.

Related sites Timothy Read's home page ScienceNOW story about TIGR's plan to sequence additional strains of anthrax Anthrax information from the Centers for Disease Control and Prevention

The results — pre-teens with MPS had thicker arterial linings than other kids their age — helped Wang secure funding for additional studies, which revealed evidence of moderate to severe heart valve disease in kids with MPS.

«There could be potential long - term therapeutic treatments that could arise from this new knowledge, which can be explored for the treatment of additional fibrotic disorders including kidney disease.»

These diseases are debilitating and involve extremely high costs to the patients, who may need to undergo dialysis, and to the health care system, for recurring hospital admissions due to additional complications.

«If Drs. Han and Zhang's hypothesis is right, then additional insights into the KLF15 pathway may not only help prevent diseases affected by bile acid amounts, but it could have major implications for drug metabolism,» Jain said.

«If the mouse models are indicative of human disease, the combination therapy can increase the proportion of patients who respond to therapy without additional adverse side effects and can improve the quality of life for cancer patients.»

«Additional recordings with FO electrodes in patients with Alzheimer's disease will help us develop better tools based on computerized analysis of EEG signals and possibly functional neuroimaging studies to ascertain how common silent seizures are in Alzheimer's disease without the need for the minimally invasive electrodes we used in these patients.»

Calling their compound a new therapeutic candidate for people with severe asthma and other chronic airway diseases, researchers say with additional research and development their discovery could lead to future clinical trials for asthma, Cystic Fibrosis and Chronic Obstructive Pulmonary Disease (COPD).

Our study suggests that the immune response to an early infection, HSV - 2, may be the additional factor that increases the risk for severity of Zika virus - induced disease,» said Dr. Gil Mor, senior author of the American Journal of Reproductive Immunology study.

To determine whether scientific studies since 2002 found additional evidence on the usefulness of omega - 3 fish oil supplements, the authors focused on studies related to preventing a first heart attack in the general population, or in patients who were at high risk for heart disease, and preventing recurrent events and death in patients who had a prior heart attack, congestive heart failure, stroke, or atrial fibrillation.

«The approach may be extended to additional complex disorders and diseases for which we don't understand the underlying biology but do have drugs that may have some beneficial actions, such as depression, anxiety, schizophrenia and others in need of more effective therapies.

Of these 34 patients, 13 (38 %) have remained in remission for five years, and an additional two patients whose disease did not progress after BV went on to achieve remission after receiving allogeneic stem cell transplant (in which healthy stem cells are taken from a donor and administered to the patient).

The Missouri Department of Health and Senior Services is working with the US Centers for Disease Control and Prevention (CDC) to identify additional cases and determine the role of this novel virus as a human pathogen.