«We've shown a causal role for this mitochondrial defect and identified a candidate biomarker
for aggressive forms of the disease.
Not exact matches
«Gene sequencing study reveals unusual mutations in endometriosis: Findings advance search
for new ways to classify
aggressive forms of the
disease.»
Women with the variant were at much higher risk
for cancer, had more recurrences, were often hit with multiple cancers and were more likely to die from
aggressive forms of these
diseases.
This provides a potential target
for treating triple negative breast cancer, the most
aggressive form of the
disease.
For years, scientists have observed that tumor cells from certain breast cancer patients with
aggressive forms of the
disease contained low levels
of mitochondrial DNA.
Frequent exposure to ultraviolet (UV) rays
for individuals under the age
of 35 increases the risk
of developing melanoma — the most
aggressive and deadliest
form of skin cancer — by 75 percent, according to the Centers
for Disease Control and Prevention.
Doctors are already using drugs, such as Herceptin, that specifically target malfunctioning genetic pathways in tumors, but no such therapies are currently available
for certain
aggressive forms of the
disease, such as the triple negative subtype.
Low Cholesterol May Shrink Risk
for High - Grade Prostate Cancer Men with lower cholesterol are less likely than those with higher levels to develop high - grade prostate cancer, an
aggressive form of the
disease with a poorer prognosis, according to results
of a Johns Hopkins collaborative study.
Many women are «triple negative» No one yet knows precisely why, but African - American women are roughly twice as likely as white women to have triple - negative breast cancer — so called because tumor cells in this particularly
aggressive form of the
disease test negative
for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER - 2).
Also, cats mount a much more
aggressive immune response against the worms than do dogs, and the resulting inflammation is responsible
for much
of the damage in the feline
form of this
disease.