Role of IL - 17A, IL - 17F, and the IL - 17 receptor in regulating growth - related oncogene - α and granulocyte colony - stimulating factor in bronchial epithelium: implications
for airway inflammation in cystic fibrosis.
In the current study, the researchers led by Drs Shigeo Koyasu from RIKEN and Koichiro Asano from Keio University, employed an experimental mouse model
for airway inflammation to study the pathway leading to IL -33-mediated NH activation.
Not exact matches
This was the first study to assess
inflammation on a tissue level and the first to discover
airway inflammation in horses not specifically selected
for poor performance.
Tobias Polte and his team from the Department of Environmental Immunology at the Helmholtz Centre
for Environmental Research (UFZ) collaborated with Jan Simon and his colleagues from the Clinic
for Dermatology, Venereology and Allergology at the University of Leipzig and have recently been successful in discovering a molecule that plays a significant role in the development of allergic
airway inflammation — as demonstrated in their recent publication in Nature Communications.
It could be a critical target with significant therapeutic potential
for suppressing
inflammation associated with chronic
airway disease.
T lymphocytes and NH cells in the asthmatic lung produce proteins named interleukin (IL)-5 and IL - 13 that are responsible
for severe
airway inflammation.
Current clinical management
for asthma focuses on reducing lung and
airway inflammation triggered by allergens, such as house dust mites, mold, etc..
Earlier findings by Dr Ferreira published in The Lancet identified that a risk factor
for asthma was a genetic variant in the IL - 6 receptor, which is activated by IL - 6 causing
inflammation in the
airways.
Our finding of sinusitis, bronchial hyperreactivity, and bronchial responsiveness in firefighters with World Trade Center cough is important but not surprising.17 - 20 An unexpected finding was that 87 percent of such firefighters reported symptoms of gastroesophageal reflux disease; such symptoms are generally reported by less than 25 percent of patients with chronic cough.1, 21,22 Despite the strong associations between gastroesophageal reflux disease and chronic cough17 - 20 and between gastroesophageal reflux disease and asthma,23 - 25 it remains unclear whether gastroesophageal reflux disease causes either condition.26 The causative mechanism may be repeated aspiration of minute amounts of refluxed material; vagally mediated esophageal, tracheobronchial, or laryngobronchial cough reflexes; or neurally mediated bronchial
inflammation.23, 24,26 Involvement of the posterior nasopharynx is common in patients with gastroesophageal reflux disease, 27 whereas bronchial hyperreactivity may not be present.25, 26
For these reasons, we classified gastroesophageal reflux disease as an upper -
airway symptom (Figure 2).
A role
for dietary selenium and selenoproteins in allergic
airway inflammation.
Arhgef1 is required by T cells
for the development of
airway hyperreactivity and
inflammation.
Career Goals: Developing of novel immunotherapeutic strategies
for the treatment of chronic allergic
inflammation and
airway remodeling.
Thus, targeting this chemokine receptor in patients with asthma might reduce Th2 cell - driven
airway inflammation; therefore, CCR4 antagonists could be an effective new therapy
for asthma.
Determining the mechanism
for these sex - based differences in
airway inflammation and the contribution of the microbiome in animal models would improve our ability to treat or prevent asthma and other autoimmune diseases in women.
For sports recovery, Lindsay says salt therapy works on the well - documented phenomenon of an athlete's suppressed immune system and
inflammation in their
airways.
In Chicago, my kids were using once - a-day Singulair pills; an inhaler
for corticosteroids, like Flovent, to fight underlying lung
inflammation; and the occasional inhaler with a bronchodilator, such as albuterol, to open up
airways if they were coughing or having other symptoms.
«COPD stands
for two processes that almost always occur together: chronic bronchitis, which is
inflammation of the
airways, and emphysema, which is destruction of the fine substance of the lung,» says Norman Edelman, MD, chief medical officer of the American Lung Association.
An option
for Neti Pot sissies like me: I like this natural saline spray with xylitol
for extra help with soothing
inflammation and opening
airways.
Omega 3: Is known mostly
for its anti-inflammatory benefits in cardiovascular disease, though it has also been recommended as helpful in decreasing
airway inflammation.
Peppermint oil is especially beneficial
for those with allergies who need help eliminating
airway inflammation.
Also, the veterinarian will use an endoscope (lighted hollow tube) to look at the throat, esophagus, and upper
airway, checking
for inflammation and erosion.
Even though steroids are not primary antitussives, by decreasing
inflammation they may decrease stimulation of
airway sensory nerves that are responsible
for initiating cough in canine CB.
Not sure about the antiemetic drug being given every 4 days
for the cough, but I think it may be cerenia, a drug more commonly used
for nausea / vomiting, but which also has been used off label
for pain and / or
inflammation of
airways.
«Feline cough has bronchitis as the most common cause which is another term
for inflammation of the
airway.
Back at the hospital, out of concern
for possible aspiration pneumonia (
inflammation of lungs and
airway as a result of breathing in foreign material — in this case, steak), Dr. Hilton and Casey's nurses took chest radiographs, which were normal.