Not exact matches
The subindication
for which now data were available
for the first time was
allogeneic SCT with related
donor in comparison with
allogeneic SCT with unrelated
donor.
HSCT is effectively used today as a form of «replacement» therapy
for patients with hard - to - treat blood cancers, providing healthy cells from either the patient (autologous transplantation) or from a
donor (
allogeneic transplantation) to better equip patients to fight the disease on their own.
Of these 34 patients, 13 (38 %) have remained in remission
for five years, and an additional two patients whose disease did not progress after BV went on to achieve remission after receiving
allogeneic stem cell transplant (in which healthy stem cells are taken from a
donor and administered to the patient).
Mehta J, Gordon LI, Tallman MS, et al., Does younger
donor age affect the outcome of reduced - intensity
allogeneic hematopoietic stem cell transplantation
for hematologic malignancies beneficially?
Allogeneic Sibling
Donor Peripheral Blood Stem Cells Transplantation With Myeloablative Conditioning
for Chronic Myeloid Leukemia in Blast Crisis - Successful Treatment Despite Severe Phase of the Disease
We are planning to develop a product that would be an
allogeneic, or
donor - derived product, that could be used
for similar indications in children and babies who don't have their own cell store.
In the future, outpatient blood and bone marrow stem cell transplantation will be offered to a broader group of patients with other blood disorders and
for allogeneic transplants (transplant from non-twin
donor stem cells).
Low - dose
donor CD8 + cells in the CD4 - depleted graft prevent
allogeneic marrow graft rejection and severe graft - versus - host disease
for chronic myeloid leukemia patients in first chronic phase.
(A and B) Flow cytometry analysis of intracellular IFN - γ and IL - 17A on
donor - derived CD4 + T cells from spleen on indicated days
for syngeneic and
allogeneic mice.
Allogeneic cell therapies from primary cells
for immunotherapy applications are especially challenging because of the vigor with which tissue
donors must be screened and qualified to prevent transmission of infectious disease and ensure maintenance of an active
donor pool.
Thus, one can transplant fully
allogeneic hematopoietic stem cells and co-transplant,
for example, hearts from the hematopoietic stem cell
donor to induce lifelong
donor - specific acceptance of the transplant, without deleterious immunosuppression [4].
It offers to the commercialization of unrelated
donor - patient (
allogeneic) cell therapy products
for the treatment of several severe degenerative, ischemic and autoimmune disorders.