Your doctor's «celiac panel» is only testing
for alpha gliadin, tissue transglutaminase 2, and endomesial antibody, a small portion of the potential immune responses to this food.
The limitations of currently available conventional testing are very real as most physicians who do a «Celiac panel» are only testing
for alpha gliadin, tissue transglutaminase 2, and endomesial antibody.
This is problematic because if gluten is in fact destroying someone's health and he or she does not test positive
for alpha gliadin but is in fact sensitive to the other components (for example Gluteomorphin), then that person who should avoid gluten, would be cleared to eat gluten containing foods.
This is important because not all who are gluten intolerant test positive
for alpha gliadin.
Not exact matches
Most modern testing focuses on only the
alpha -
gliadin (one of the twelve sub-fractions) and therefore leaves considerable room
for error and false negative tests.
As mentioned earlier, standard testing
for gluten intolerance only tests
for antibodies to one component of gluten,
alpha gliadin.
Most tests only check
for antibodies to
alpha -
gliadin (one single gluten peptide), and not everyone with a gluten sensitivity reacts to that particular gluten peptide.
If you see a conventional medical doctor and have your blood tested at a conventional medical laboratory
for celiac disease / gluten sensitivity, you will be tested
for IgA and IgG antibodies to the 33 - mer peptide of deamidated
alpha -
gliadin and transglutaminase 2.
Standard tests only screen
for one,
alpha gliadin.
If you ask to be screened
for gluten intolerance, that screening will typically include antibodies to only
alpha gliadin, endomesial antibody, and one type of tissue transglutaminase.