The group's results show that MTs are responsible for elongation of the zygote along the top - bottom axis, whereas F - actin plays a role in moving the nucleus towards the top part of the zygote, to make it ready
for asymmetric cell division.
Not exact matches
Ueda's group also discovered HOMEODOMAIN GLABROUS11 (HDG11) and HDG12, the factors derived from the egg
cells, which are responsible
for controlling the
asymmetric division of the zygote and development of the embryo.
But in a process called
asymmetric division, a
cell divides into two daughters that are not identical — a skin stem
cell divides into another skin stem
cell and a regular skin
cell,
for example.
The group succeeded in visualizing
for the first time, how the cytoskeleton of plant egg
cells is disassembled after fertilization and then reorganized to create a polarity in the
cell that eventually leads to
asymmetric cell division.
In parallel, the roles of symmetric and
asymmetric cell divisions are investigated as a mechanism
for governing stem
cell self - renewal and differentiation during embryonic development and in the adult.
For his postdoc, he joined the laboratory of Lily and Yuh Nung Jan at University of California San Francisco to analyse the mechanisms of
asymmetric cell division.
Vascular
Cell Biology New Roles for BMP Signaling in Angiogenesis Victoria Bautch, University of North Carolina, Chapel Hill Coordination of angiogenesis by asymmetric cell division Shane Herbert, University of Manche
Cell Biology New Roles
for BMP Signaling in Angiogenesis Victoria Bautch, University of North Carolina, Chapel Hill Coordination of angiogenesis by
asymmetric cell division Shane Herbert, University of Manche
cell division Shane Herbert, University of Manchester