These results, published today (December 12) in Nature Biotechnology, have implications
for autologous transplantation — creating a replacement tissue from a patient's own cells — something that older people are more likely to need, the authors noted.
Patient - derived organoids offer great promise for application in the field of translational medicine, in particular
for autologous transplantation and tissue regeneration purposes (4 - 6).
Not exact matches
The search
for new or supplementary study data in the subindication of multiple
autologous transplantation produced no result: There are three large studies that are known from the publication of abstracts to have been completed
for a long time.
Autologous hematopoietic stem cell
transplantation (AHSCT) has been investigated as a treatment
for aggressive MS, the rationale
for which is immune reconstitution.
HSCT is effectively used today as a form of «replacement» therapy
for patients with hard - to - treat blood cancers, providing healthy cells from either the patient (
autologous transplantation) or from a donor (allogeneic
transplantation) to better equip patients to fight the disease on their own.
«These findings give a rationale to start
autologous transplantation — at least of neural cells — in clinical situations,» says senior author Dr. Jun Takahashi, of the Kyoto University's Center
for iPS Cell Research and Application.
This novel and informative work may provide an immunologic explanation
for the observed therapeutic efficacy of
autologous HSPC
transplantation in T1D and pave the way
for new therapeutic interventions in the future.
A national study on conditional survival, excess mortality and second cancer after high dose therapy with
autologous stem cell
transplantation for non-Hodgkin lymphoma.
Conditional survival and excess mortality after high - dose therapy with
autologous stem cell
transplantation for adult refractory or relapsed Hodgkin lymphoma in Norway.
Plerixafor has been approved by the FDA as the first small - molecule CXCR4 antagonist
for use in combination with granulocyte - colony stimulating factor (GCSF) to mobilize hematopoietic stem cells to the bloodstream
for collection and subsequent
autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma.
Although
autologous cell
transplantation circumvents the need
for immunosuppressive treatment, it is not always available or most effective.
High - Dose Chemotherapy Plus Transplant Not Recommended
for DLBCL: The results of an Italian study report that treatment of high - risk diffuse large B - cell lymphoma (DLBCL) with abbreviated course of rituximab dose - dense chemotherapy plus high - dose cytarabine, mitoxantrone, and dexamethasone (R - MAD) plus carmustine, etoposide, cytarabine, and melphalan (BEAM) plus
autologous stem cell
transplantation compared with a full course of rituximab dose - dense chemotherapy did not improve overall survival.
CRP Levels Before Transplant Linked With Survival in Multiple Myeloma: According to a new study, patients with an elevation in C - reactive protein (CRP) prior to an
autologous stem cell
transplantation (ASCT)
for multiple myeloma experienced a worse overall survival (OS) rate.
For example, we're one of a handful of hospitals in the country to offer total pancreatectomy with islet cell autotransplantation (
autologous islet cell
transplantation), a procedure aimed at preventing diabetes or reducing its effects after removal of the pancreas due to pancreatitis.
A comprehensive coping strategy programme reduced nausea and fatigue after
autologous bone marrow
transplantation for breast cancer
Is it feasible to conduct a randomised controlled trial of pretransplant exercise (prehabilitation)
for patients with multiple myeloma awaiting
autologous haematopoietic stem cell
transplantation?
See: See: A comprehensive coping strategy programme reduced nausea and fatigue after
autologous bone marrow
transplantation for breast cancer.