Several of these are known to be important for neural development in worms — for example, the gene cle - 1 is needed
for axon guidance.
is needed
for axon guidance.
«We found that the steepness of the gradient is a critical factor
for axon guidance; the steeper the gradient, the better the axons respond to guidance cues,» says Tyler F.W. Sloan, PhD student in Dr. Charron's laboratory and first author of the study.
Not exact matches
Over the past few decades, the scientific community has struggled to understand why more than one
guidance cue would be necessary
for axons to reach the proper target.
«A better understanding of the mechanisms involved in
axon guidance will offer new possibilities
for developing techniques to treat lesions resulting from spinal cord injuries, and possibly even neurodegenerative diseases.»
Misrouting has been attributed to the absence of the directional cues required
for normal RGC
axon guidance.
Our studies reveal previously - unknown roles
for glia in pioneer -
axon guidance, and suggest conserved principles of brain formation.