Sentences with phrase «for cadherin»

Nectins tend to bind heterophilically, meaning that they adhere more strongly to nectins of a different type, and have been shown to serve as recruiters for cadherin molecules.

Not exact matches

These findings suggest that the therapeutic protein was able to interact normally with its binding partners among the USH1 molecular complex (the proteins cadherin 23, protocadherin 15, myosin VIIA and harmonin), as required for the mechanoelectrical transduction apparatus of the hair bundle to function correctly.

Not only did they show that N - cadherin was necessary for creating the perfectly clear structure of the lens, they also observed that malformed lenses lacking N - cadherin began to attract immune cells to try to fix the damage.

However, two types of cells in the olfactory epithelium (specialized tissue responsible for sense of smell), are mixed together and form a mosaic pattern despite expressing different types of cadherins.

«Not only that, but the more cadherin - 22 that there is in a tumour, the more advanced the cancer stage and the worse the prognosis is for the patients.»

«Cadherin - 22 could be a powerful prognostic marker for advanced cancer stages and patient outcomes,» said lead author Prof. Jim Uniacke, Department of Molecular and Cellular Biology.

The culprit in the condition, called aortic valve stenosis, is cadherin - 11, a binding protein necessary for normal wound healing.

«Our findings suggest that cadherin - 11 is important for cancer progression as well as rheumatoid arthritis — for reasons we do not fully understand.

For both cancer types, the research team used molecular tools to reduce the amount of cadherin - 22.

He explains, «cadherins were mostly known for their role in the maintenance of normal tissue structure.

The researchers learned that the astonishing diversity of cadherin in pink bollworm from India is caused by alternative splicing, a novel mechanism of resistance that allows a single DNA sequence to code for many variants of a protein.

Further experiments revealed that cadherins, proteins that keep cells joined to each other, are required for entosis.

Cooper, Jossin find surprising new role for N - cadherin; finding could shed light on how normal and cancerous cells migrate within the body

Amphimedon cadherins differ from those of Monosiga in having proteins with domain architectures diagnostic for the metazoan - specific classical cadherin and seven pass transmembrane cadherin subfamilies31, 35.

To explore the possibility of common genetic pathways within the respective pathophysiologies, nine ADHD candidate single nucleotide polymorphisms (SNPs) in seven genes were tested for association with PD in 5333 cases and 12,019 healthy controls: one variant, respectively, in the genes coding for synaptosomal - associated protein 25 k (SNAP25), the dopamine (DA) transporter (SLC6A3; DAT1), DA receptor D4 (DRD4), serotonin receptor 1B (HTR1B), tryptophan hydroxylase 2 (TPH2), the norepinephrine transporter SLC6A2 and three SNPs in cadherin 13 (CDH13).