Sentences with phrase «for cancer cell invasion»

Not exact matches

EMT is important for cell migration and invasion — two characteristic of metastatic cancer cells — strongly suggesting that the link between lncRNAs and EMT contributes to the metastatic progression of ovarian cancer.

«I think what's needed for collective invasion will depend on the environmental stresses the cancer cells face, and it may shift with treatment,» Marcus says.

Kruppel - like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion

The authors conclude that their six hallmarks — sustained proliferative signaling, evading growth suppression, resisting cell death, replicative immortality, induction of angiogenesis, and invasion / metastasis — continue to provide a useful conceptual framework for understanding the biology of cancer.

Prostate Cancer: CXCR4 is important for the invasion and metastasis of prostate cancer cells to the bone marrow [32, 38] and it is also a prognostic factor for prostate cancer patientsCancer: CXCR4 is important for the invasion and metastasis of prostate cancer cells to the bone marrow [32, 38] and it is also a prognostic factor for prostate cancer patientscancer cells to the bone marrow [32, 38] and it is also a prognostic factor for prostate cancer patientscancer patients [39].

Through its various targets, MMP1 promotes not only tumor invasion but also breast cancer colonization to bone by mechanisms that include the release of membrane - bound EGF - like growth factors from tumor cells, leading to activation of EGF receptor signaling and suppression of OPG expression in osteoblasts, which in turn promotes the differentiation and activation of osteoclasts required for bone destruction and enhanced tumor growth in the bone microenvironment (32).

However, it remains unclear whether CAFs directly stimulate cancer cell invasion or they remodel the extracellular matrix to make it more permissive for invasion.

The extent of this cell invasion into the ECM is a key medical marker for cancer prognosis.

Their three - dimensional cell - culture system, adapted for high - throughput screening, has enabled them to identify small molecules that can inhibit adhesion and invasion, preventing ovarian cancers from spreading to nearby tissues.

A «WOW» maple syrup finding: Take this 2015 study reported in Oncology Reports: the researchers examined the effect of three grades of maple syrup (grades are based on the color of the syrup and ranges from light to darker with color being influenced by time of year and processing technique) on the proliferation, migration, and invasion of colorectal cancer (CRC) cells in order to investigate whether maple syrup is suitable as a phytomedicine for cancer treatment.