Sentences with phrase «for cell»

This method is a new tool for cell biologists and neuroscientists to use to address questions ranging from fundamental mechanisms in cell biology, to the underlying causes of mental illness, to the discovery of novel therapeutics.

But for cell replacement therapy to realize its potential, I anticipate that scientists must solve the developmental code, the set of rules that govern the formation of tissues, organs, and beings from the original single cell — the zygote.

Another challenge was to adapt the analysis techniques used for the cell molecules — for measuring enzyme activity, for example — to the minute measurement volumes.

This approach could also be used in many different contexts, not only for cell cycle analysis,» adds Prof. Dr. Dr. Fabian Theis, head of the ICB.

They have discovered that a single amino acid difference in the structure of histone H3.3 enables it to serve as a kind of memory device for the cell, marking genes that need to remain active.

They are associated with the cell cytoskeleton — a complex network of interlinking filaments inside the cell that is necessary for cell migration — making them viable targets for inhibiting migration.

One key to achieving efficient semitransparent solar cells is to develop a transparent electrode for the cell's uppermost layer that is compatible with the photoactive material.

The same goes for another cell membrane protein, LAG - 3, which is present in neurons and which was recently described in Science as binding tightly to the rogue Parkinson's protein.

In vivo and in vitro experiments showed that, among many biochemical effects, 14 -3-3 sigma suppresses cancer glycosis, which prevents cancer's ability to convert glucose into pyruvate, a substance essential for cell growth.

Those caps make it impossible for a cell to read the specific genes they are attached to.

The best example of this occurs in what's called gene imprinting, where for example, females have two X chromosomes and one of those two X chromosomes must be inactivated in a cell in order for the cell's normal function.

Microbiologists must wait for cell cultures to grow.

Using a high - speed actuator as the driving source of pump, they succeeded in producing a flow with 16 microseconds for cell sorting.

EMT is important for cell migration and invasion — two characteristic of metastatic cancer cells — strongly suggesting that the link between lncRNAs and EMT contributes to the metastatic progression of ovarian cancer.

His work has been recognized by the GE & Science Prize for Young Life Scientists, the Michael and Kate Bárány Award, the American Society for Cell Biology - Gibco Emerging Leader Prize, and the Vilcek Prize for Creative Promise.

As a result, S - adenosyl methionine was available for these epigenetic modifications that are required for a cell to enter the primed state.

«Compared to the size of the cells, these bumps on existing implants are so large that they're effectively a smooth cliff face compared to the dimensions required for the cell to interact with.

They injected a mutant gene for a cell - surface receptor for bmp into the right legs of two - day - old chicken embryos.

As a result, reduced abilities for cell growth, migration and invasion were found.

After sending the image to a preassigned HP number (via SMS, the standard data transmission protocol for cell phones), it will be processed by computers employing algorithms capable of identifying both the user's face and the sheet of color swatches.

In addition, it provides a marker for cell fates and insight into the molecular and cellular mechanisms by which FSC progeny diverge into distinct fates.

It found that microRNA - 486 (miR - 486) directly targets the insulin growth - factor pathway, which is important for cell survival and proliferation.

Over time, the telomeres become too short for the cell to divide and they become «senescent.»

Svetlana Glushakova, a cell biologist at the National Institute of Child Health and Human Development in Bethesda, Md., reported the finding December 9 at the annual meeting of the American Society for Cell Biology.

By identifying the genes in any given taste cell, scientists can pinpoint the unique molecular components needed for that cell to carry out its particular function.

Researchers at the Energy Department's National Renewable Energy Laboratory (NREL) are turning to extremely tiny tubes and rods to boost power and durability in lithium - ion batteries, the energy sources for cell phones, laptops, and electric vehicles.

«Many research groups are looking at how genes are regulated from the perspective of which genes need to be turned «on» for a cell to advance to the next stage of development, but now we see that it's just as important to know which genes need to be turned «off,»» Cook - Andersen said.

«We want to make an active miRNA dictionary for each cell type, so that if we want to isolate this kind of cell type, we know how to use this kind of switch,» he said.

In a report that appears in PLOS BIOLOGY, Dr. Hugo Bellen and his colleagues at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and BCM, and Dr. Chao Tong, at the Life Sciences Institute and Innovation Center for Cell Biology, Zhejiang University in Hangzhou, China, find that mutations of human homologs (genes that carry out similar functions) of cacophony and its partner straightjacket (Cacna1a and Cacna2d2 respectively) cause defects in autophagy in neurons.

Their study, the researchers say «establishes a role for cell wall - associated GAG in mediating resistance to killing of Aspergillus by NETs and provides the first example of a virulence factor of A. fumigatus that is able to mediate enhanced virulence when expressed in a less pathogenic Aspergillus species».

At the Center for Cell and Gene Therapy at Baylor College of Medicine in Houston, director Malcolm Brenner, a geneticist, says he has turned «AdV from poacher into gamekeeper.»

The DNA in human cells is translated into a multitude of proteins required for a cell to function.

«Breast cancer stem cells pose a serious problem for therapy,» says lead study investigator Gregg Semenza, M.D., Ph.D., the C. Michael Armstrong Professor of Medicine, director of the Vascular Biology Program at the Johns Hopkins Institute for Cell Engineering and a member of the Johns Hopkins Kimmel Cancer Center.

Actin is a crucial molecule for cell motility throughout the body.

«But we need more examples of where it really matters for cell function,» Gladfelter says.

Researchers found that in N. gonorrhoeae, BamE is exposed on the cell surface but is not essential for cell viability.

Microtubules even come into play on the outside of cells, forming into cilia and flagella that allow for cell movement.

In a boon to stem cell research and regenerative medicine, scientists at Boston Children's Hospital, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Boston University have created a computer algorithm called CellNet as a «roadmap» for cell and tissue engineering, to ensure that cells engineered in the lab have the same favorable properties as cells in our own bodies.

«In these diseases of mitochondrial dysfunction, in a sense, it's a false starvation situation for the cell — there are plenty of nutrients, but because there's a block in the mitochondria's normal function, the mitochondria behave as if there's not enough oxygen,» says Chen, who with Birsoy, authored a paper in the journal Cell Reports describing this work.

Existing gels for cell culture are often animal derived, which can affect the reproducibility of results or, if synthetic, require coatings or coupling of cell - adhesive ligands.

The device continuously monitors conditions within the microfluidic chip, including oxygen levels, temperature, and pH, to ensure the optimum environment for cell growth.

Researchers at the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children's Hospital and Houston Methodist have developed an alternative treatment in which virus - specific cells protect patients against severe, drug - resistant viral infections.

«It makes perfect sense for the cell to have such a mechanism and not even try to produce RNA when its building blocks are lacking.»

RNA, like DNA, encodes information for cell functions, but RNA can also fold up and perform tasks, like signaling, regulating or catalyzing reactions.

CdLS is known to result from mutations in subunits or regulators of cohesin, a group of linked proteins necessary for cell division and other cell processes.

This has potential applications for cell replacement without the immunosuppression treatments that are required when cells are transferred between genetically different individuals.

DNA is not the only medium for communicating information necessary for cell function.

For cell lines, one might report the source, authentication, and mycoplasma contamination status.

«Reducing protein production in aging neurons allows more energy for the cell to put toward folding proteins correctly and handling stress,» says Zheng, the first author of the new paper.

«The greatest demand is for cell biologists, molecular biologists, and protein chemists.