The research team at Mainz University speculates that whilst entanglements between chromosomes need to be removed
for cell cycle progression those within a chromosome may not affect function and transmission of genetic information.
Once freed, the proteasome degrades proteins required
for cell cycle progression, thus driving cells into senescence.
Not exact matches
c - Rel is essential
for B lymphocyte survival and
cell cycle progression.
Stat5 Is required
for IL -2-induced
cell cycle progression of peripheral T
cells.
Hsiou - Chi Liou and colleagues find that c - Rel, a lymphoid - specific member of the NF - kappaB / Rel family of transcriptional factors, is essential
for B lymphocyte survival and
cell cycle progression, [i] and that it is important
for inducible cytokine and cytokine receptor expression and a key regulator of early activation and proliferation in T
cells.
Drosophila Ctf4 is essential
for efficient DNA replication and normal
cell cycle progression.
Pax - 7 up - regulation inhibits myogenesis and
cell cycle progression in satellite
cells: a potential mechanism
for self - renewal.
«Treatment
for HIV currently relies on drugs which target the viruses
cell -
cycle to slow HIV replication (and the
progression to AIDS)(called antiretroviral therapy (ART).
The role of
cell cycle checkpoint proteins is to integrate internal and external factors to determine whether the
cell is prepared
for progression of the
cell cycle.
Our favorite experimental system is the Xenopus egg extract system
for studies on
cell cycle progression and regulation, microtubule dynamics, spindle assembly and chromosome behaviour (Karsenti and Vernos, 2001).
Validation of a
cell cycle progression score
for five - year mortality risk in patients with stage I lung adenocarcinoma.
In response to DNA damage, the checkpoint regulates and coordinates many cellular processes critical
for genomic stability, including
cell cycle progression, DNA repair, DNA replication, and apoptosis.