Hypermethylation of DNA is a key epigenetic mechanism for the silencing of many genes, including
those for cell cycle regulation, receptors, DNA repair, and apoptosis (5, 6, 7, 8).
Not exact matches
CDKs are crucial
for the
regulation of the
cell cycle.
«We suspect that faults in
cell -
cycle regulation account
for a variety of developmental brain diseases.»
Pax - 7 up -
regulation inhibits myogenesis and
cell cycle progression in satellite
cells: a potential mechanism
for self - renewal.
Stathmin is essential
for the
regulation of the
cell cytoskeleton, which is required
for numerous
cell processes including regulating the
cell cycle, cytoplasmic organization,
cell division and
cell motility...
Our favorite experimental system is the Xenopus egg extract system
for studies on
cell cycle progression and
regulation, microtubule dynamics, spindle assembly and chromosome behaviour (Karsenti and Vernos, 2001).
Activation of the cdk inhibitory protein p21 by ellagic acid suggests a role
for ellagic acid in
cell cycle regulation of cancer
cells.
Melanopsin
cells in mammals are specialized
for measuring ambient illumination, contributing to visual discrimination [8,9], and driving a wide variety of physiological responses including, but not restricted to: synchronization of circadian clocks to light: dark
cycles,
regulation of pupil size, modulation of sleep and suppression of pineal melatonin production [10 — 14].